STRINGSTRING
mcm3 mcm3 mcm6.2 mcm6.2 A0A1L8EK84 A0A1L8EK84 Xcdc6 Xcdc6 Psmd3.S Psmd3.S psmd11 psmd11 psmc5 psmc5 A0A1L8ELN4 A0A1L8ELN4 A0A1L8ELP7 A0A1L8ELP7 rbl1 rbl1 e2f1 e2f1 Mybl2.S Mybl2.S Psmd12.S Psmd12.S Orc2.S Orc2.S psmd3 psmd3 Cdc6.L Cdc6.L psmd11-2 psmd11-2 A0A1L8ESV8 A0A1L8ESV8 cables2 cables2 A0A1L8ET61 A0A1L8ET61 Rbl1.L Rbl1.L Psmd12.L Psmd12.L Mcm6.2.L Mcm6.2.L orc4 orc4 A0A1L8EWW0 A0A1L8EWW0 Meiob.L Meiob.L A0A1L8EZQ1 A0A1L8EZQ1 Mnat1.S Mnat1.S A0A1L8EZW5 A0A1L8EZW5 akt1 akt1 Psmc6.S Psmc6.S ppp4r4 ppp4r4 psmc1 psmc1 lin52 lin52 A0A1L8F0R3 A0A1L8F0R3 Psmd10.S Psmd10.S A0A1L8F3B0 A0A1L8F3B0 A0A1L8F3K4 A0A1L8F3K4 Psmb9.S Psmb9.S MGC78893 MGC78893 Psmd8.S Psmd8.S A0A1L8F575 A0A1L8F575 psmb4 psmb4 A0A1L8F5A2 A0A1L8F5A2 psmd5 psmd5 psmb7 psmb7 fndc3c fndc3c akt2 akt2 Psmd8.L Psmd8.L A0A1L8F982 A0A1L8F982 Psmc1.L Psmc1.L ppp4r4-2 ppp4r4-2 Pole2.L Pole2.L psmc6 psmc6 A0A1L8FA58 A0A1L8FA58 mnat1 mnat1 ppp2r3c ppp2r3c Psmb4.L Psmb4.L A0A1L8FDD6 A0A1L8FDD6 Cks1b.S Cks1b.S Xicl Xicl A0A1L8FHE3 A0A1L8FHE3 A0A1L8FHF8 A0A1L8FHF8 A0A1L8FHS2 A0A1L8FHS2 A0A1L8FHS4 A0A1L8FHS4 A0A1L8FHT5 A0A1L8FHT5 A0A1L8FHT9 A0A1L8FHT9 A0A1L8FHW4 A0A1L8FHW4 A0A1L8FLR1 A0A1L8FLR1 A0A1L8FPG2 A0A1L8FPG2 A0A1L8FPJ2 A0A1L8FPJ2 dyrk1a.2 dyrk1a.2 A0A1L8FQZ7 A0A1L8FQZ7 A0A1L8FRQ0 A0A1L8FRQ0 psma2 psma2 relch relch Ppp4r1.S Ppp4r1.S cables1 cables1 mcm4 mcm4 lyn lyn A0A1L8FTA7 A0A1L8FTA7 e2f5 e2f5 Ccne2.S Ccne2.S dbf4 dbf4 mcm6 mcm6 A0A1L8FXN2 A0A1L8FXN2 e2f3 e2f3 Gmnn.L Gmnn.L ppp4r1 ppp4r1 cables1-2 cables1-2 Mcm4.S Mcm4.S lyn-2 lyn-2 Orc5.L Orc5.L e2f5-2 e2f5-2 Ccne2.L Ccne2.L lin9 lin9 orc3 orc3 prim2 prim2 Psmd2.S Psmd2.S A0A1L8G3T0 A0A1L8G3T0 fndc3b fndc3b tfdp2 tfdp2 Ppp2r3a.S Ppp2r3a.S A0A1L8G5V1 A0A1L8G5V1 A0A1L8G614 A0A1L8G614 Lin9.L Lin9.L mcm9 mcm9 Psmd2.L Psmd2.L fndc3b-2 fndc3b-2 A0A1L8GBD0 A0A1L8GBD0 Tfdp2.L Tfdp2.L A0A1L8GBH4 A0A1L8GBH4 zmcm3 zmcm3 Psmd13.S Psmd13.S A0A1L8GDE6 A0A1L8GDE6 Wee1.S Wee1.S prr5l prr5l Psma1.S Psma1.S psmd7 psmd7 e2f4 e2f4 Cdt1.S Cdt1.S Ccne1.S Ccne1.S cdkn2c cdkn2c mcm5 mcm5 mcm2 mcm2 A0A1L8GI18 A0A1L8GI18 Wee1.L Wee1.L prr5l-2 prr5l-2 fnbp4 fnbp4 pola2 pola2 A0A1L8GJU9 A0A1L8GJU9 rbl2 rbl2 ccne1 ccne1 Orc6.L Orc6.L e2f4-2 e2f4-2 A0A1L8GLZ6 A0A1L8GLZ6 Orc1.L Orc1.L cdkn2c-2 cdkn2c-2 A0A1L8GMX9 A0A1L8GMX9 A0A1L8GN61 A0A1L8GN61 mcm5-2 mcm5-2 Mcm2.L Mcm2.L Wee2 Wee2 A0A1L8GQL8 A0A1L8GQL8 Cdkn1b.S Cdkn1b.S ppp2ca ppp2ca skp1 skp1 psmc2 psmc2 A0A1L8GWC5 A0A1L8GWC5 skp1-2 skp1-2 Pole4.L Pole4.L mcm10 mcm10 cdkn2d cdkn2d MCM7 MCM7 A0A1L8H4R2 A0A1L8H4R2 A0A1L8H5C2 A0A1L8H5C2 Pola1.S Pola1.S A0A1L8H6B5 A0A1L8H6B5 Psmb2.S Psmb2.S A0A1L8H8T3 A0A1L8H8T3 A0A1L8H8T6 A0A1L8H8T6 A0A1L8H8U7 A0A1L8H8U7 rb1 rb1 Cdk2.S Cdk2.S fndc3a fndc3a Ccna1.S Ccna1.S A0A1L8HB55 A0A1L8HB55 Cdk4.L Cdk4.L A0A1L8HCE8 A0A1L8HCE8 A0A1L8HCZ9 A0A1L8HCZ9 Rpa1.L Rpa1.L cdkn1a cdkn1a tfdp1 tfdp1 Cdk2.L Cdk2.L fndc3a-2 fndc3a-2 Ccna1.L Ccna1.L Ccna2.S Ccna2.S kxd1 kxd1 cdkn2b cdkn2b cks2 cks2 Psme1.S Psme1.S A0A1L8HPK4 A0A1L8HPK4 psmb5 psmb5 Cdc45.S Cdc45.S ubc ubc Kxd1.L Kxd1.L A0A1L8HX68 A0A1L8HX68 psmb5-2 psmb5-2 pole pole cdc45 cdc45 Cdk7.L Cdk7.L A0A1L8I2J2 A0A1L8I2J2 Skp2.L Skp2.L A0A310TNW1 A0A310TNW1 Cdk6.L Cdk6.L LOC398610 LOC398610 e2f1-2 e2f1-2 cks2-2 cks2-2 psmc2-2 psmc2-2 ccnd2 ccnd2 psmc3-a psmc3-a gmnn gmnn cdkn2b-2 cdkn2b-2 ccnd2-2 ccnd2-2 psmb6 psmb6 ccna2 ccna2 ccnh-A ccnh-A MGC114992 MGC114992 psma1 psma1 Psmb3 Psmb3 psmb3 psmb3 psmd10 psmd10 rpa3 rpa3 psmf1 psmf1 psme3 psme3 psme1 psme1 ccndx ccndx psmd7-2 psmd7-2 psmb7-2 psmb7-2 rpa3-2 rpa3-2 psma6 psma6 cdkn2d-2 cdkn2d-2 psmd9 psmd9 psme2 psme2 rps27a rps27a psma5 psma5 psmb2 psmb2 psmc5-2 psmc5-2 uba52 uba52 psme3-2 psme3-2 pole3 pole3 ubc-2 ubc-2 psmb7.2 psmb7.2 psma4 psma4 psmc3 psmc3 ppp2r1a ppp2r1a psmd14 psmd14 psmd6 psmd6 psmb1 psmb1 ppp2r1b ppp2r1b prim1 prim1 psmd9-2 psmd9-2 psma3 psma3 ccnd1 ccnd1 cdknx cdknx psmb8 psmb8 ppp2cb ppp2cb e2f3-2 e2f3-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mcm3DNA helicase; Belongs to the MCM family. (807 aa)
mcm6.2DNA helicase; Belongs to the MCM family. (825 aa)
A0A1L8EK84Uncharacterized protein. (77 aa)
Xcdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (554 aa)
Psmd3.SPCI domain-containing protein. (498 aa)
psmd11PCI domain-containing protein. (422 aa)
psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
A0A1L8ELN4WRNPLPNID domain-containing protein. (921 aa)
A0A1L8ELP7CtIP_N domain-containing protein. (643 aa)
rbl1Uncharacterized protein. (1047 aa)
e2f1E2F_TDP domain-containing protein. (427 aa)
Mybl2.SUncharacterized protein. (622 aa)
Psmd12.SPCI domain-containing protein. (455 aa)
Orc2.SUncharacterized protein. (558 aa)
psmd3PCI domain-containing protein. (547 aa)
Cdc6.LCell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (645 aa)
psmd11-2PCI domain-containing protein. (422 aa)
A0A1L8ESV8CtIP_N domain-containing protein. (669 aa)
cables2Cyclin N-terminal domain-containing protein. (470 aa)
A0A1L8ET61WRNPLPNID domain-containing protein. (917 aa)
Rbl1.LUncharacterized protein. (1049 aa)
Psmd12.LPCI domain-containing protein. (455 aa)
Mcm6.2.LDNA helicase; Belongs to the MCM family. (823 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (432 aa)
A0A1L8EWW0Uncharacterized protein. (1359 aa)
Meiob.LUncharacterized protein. (470 aa)
A0A1L8EZQ1Proteasome subunit alpha type. (236 aa)
Mnat1.SRING-type domain-containing protein. (294 aa)
A0A1L8EZW5Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (352 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
Psmc6.SAAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
ppp4r4Uncharacterized protein. (874 aa)
psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
lin52Uncharacterized protein. (112 aa)
A0A1L8F0R3Uncharacterized protein. (136 aa)
Psmd10.SANK_REP_REGION domain-containing protein. (270 aa)
A0A1L8F3B0Uncharacterized protein. (1205 aa)
A0A1L8F3K4Proteasome subunit beta. (279 aa)
Psmb9.SProteasome subunit beta. (215 aa)
MGC78893Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (485 aa)
Psmd8.SPCI domain-containing protein. (271 aa)
A0A1L8F575Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (167 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (249 aa)
A0A1L8F5A2VWFA domain-containing protein. (635 aa)
psmd5Uncharacterized protein. (505 aa)
psmb7Proteasome subunit beta. (277 aa)
fndc3cUncharacterized protein. (1205 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa)
Psmd8.LPCI domain-containing protein. (271 aa)
A0A1L8F982Uncharacterized protein. (96 aa)
Psmc1.LAAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ppp4r4-2Uncharacterized protein. (873 aa)
Pole2.LDNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (569 aa)
psmc6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
A0A1L8FA58Non-specific serine/threonine protein kinase. (516 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
ppp2r3cEF-hand_13 domain-containing protein. (448 aa)
Psmb4.LProteasome subunit beta; Belongs to the peptidase T1B family. (249 aa)
A0A1L8FDD6VWFA domain-containing protein. (377 aa)
Cks1b.SCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (165 aa)
XiclUncharacterized protein. (266 aa)
A0A1L8FHE3Cyclin_C domain-containing protein. (152 aa)
A0A1L8FHF8CYCLIN domain-containing protein; Belongs to the cyclin family. (72 aa)
A0A1L8FHS2Uncharacterized protein. (243 aa)
A0A1L8FHS4Prot_ATP_ID_OB domain-containing protein. (59 aa)
A0A1L8FHT5AAA domain-containing protein. (240 aa)
A0A1L8FHT9Uncharacterized protein. (94 aa)
A0A1L8FHW4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (315 aa)
A0A1L8FLR1Uncharacterized protein. (661 aa)
A0A1L8FPG2Uncharacterized protein. (137 aa)
A0A1L8FPJ2Uncharacterized protein. (114 aa)
dyrk1a.2Protein kinase domain-containing protein. (671 aa)
A0A1L8FQZ7Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (329 aa)
A0A1L8FRQ0CULLIN_2 domain-containing protein; Belongs to the cullin family. (701 aa)
psma2Proteasome subunit alpha type. (234 aa)
relchLisH domain-containing protein. (1217 aa)
Ppp4r1.SWRNPLPNID domain-containing protein. (944 aa)
cables1Cyclin N-terminal domain-containing protein. (549 aa)
mcm4DNA helicase; Belongs to the MCM family. (858 aa)
lynTyrosine-protein kinase. (508 aa)
A0A1L8FTA7Ubiquitin-like domain-containing protein. (105 aa)
e2f5E2F_TDP domain-containing protein. (371 aa)
Ccne2.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (430 aa)
dbf4Uncharacterized protein. (661 aa)
mcm6DNA helicase; Belongs to the MCM family. (821 aa)
A0A1L8FXN2LisH domain-containing protein. (1238 aa)
e2f3E2F_TDP domain-containing protein. (425 aa)
Gmnn.LUncharacterized protein. (213 aa)
ppp4r1Uncharacterized protein. (905 aa)
cables1-2Cyclin N-terminal domain-containing protein. (563 aa)
Mcm4.SDNA helicase; Belongs to the MCM family. (863 aa)
lyn-2Tyrosine-protein kinase. (508 aa)
Orc5.LAAA_16 domain-containing protein. (440 aa)
e2f5-2E2F_TDP domain-containing protein. (371 aa)
Ccne2.LCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (397 aa)
lin9DIRP domain-containing protein. (562 aa)
orc3ORC_WH_C domain-containing protein. (709 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (513 aa)
Psmd2.S26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (899 aa)
A0A1L8G3T026S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (922 aa)
fndc3bUncharacterized protein. (1205 aa)
tfdp2Transcription factor. (376 aa)
Ppp2r3a.SUncharacterized protein. (1127 aa)
A0A1L8G5V1Ubiquitin-like domain-containing protein. (156 aa)
A0A1L8G614MCM domain-containing protein; Belongs to the MCM family. (798 aa)
Lin9.LDIRP domain-containing protein. (562 aa)
mcm9MCM domain-containing protein; Belongs to the MCM family. (1143 aa)
Psmd2.L26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (899 aa)
fndc3b-2Uncharacterized protein. (1204 aa)
A0A1L8GBD0Uncharacterized protein. (1125 aa)
Tfdp2.LUncharacterized protein. (274 aa)
A0A1L8GBH4Uncharacterized protein. (148 aa)
zmcm3DNA helicase; Belongs to the MCM family. (806 aa)
Psmd13.SPCI domain-containing protein. (364 aa)
A0A1L8GDE6Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (286 aa)
Wee1.SWee1-like protein kinase. (595 aa)
prr5lUncharacterized protein. (363 aa)
Psma1.SProteasome subunit alpha type. (295 aa)
psmd7MPN domain-containing protein. (320 aa)
e2f4E2F_TDP domain-containing protein. (375 aa)
Cdt1.SCDT1 domain-containing protein. (615 aa)
Ccne1.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
cdkn2cANK_REP_REGION domain-containing protein. (168 aa)
mcm5DNA helicase; Belongs to the MCM family. (735 aa)
mcm2DNA helicase; Belongs to the MCM family. (885 aa)
A0A1L8GI18Uncharacterized protein. (364 aa)
Wee1.LWee1-like protein kinase. (618 aa)
prr5l-2Uncharacterized protein. (396 aa)
fnbp4Uncharacterized protein. (915 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (673 aa)
A0A1L8GJU9CRC domain-containing protein. (226 aa)
rbl2Uncharacterized protein. (1087 aa)
ccne1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
Orc6.LUncharacterized protein. (252 aa)
e2f4-2E2F_TDP domain-containing protein. (374 aa)
A0A1L8GLZ6Proteasome subunit alpha type. (261 aa)
Orc1.LOrigin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (886 aa)
cdkn2c-2ANK_REP_REGION domain-containing protein. (168 aa)
A0A1L8GMX9Protein kinase domain-containing protein. (509 aa)
A0A1L8GN61Uncharacterized protein. (244 aa)
mcm5-2DNA helicase; Belongs to the MCM family. (735 aa)
Mcm2.LDNA helicase; Belongs to the MCM family. (886 aa)
Wee2Wee1-like protein kinase. (534 aa)
A0A1L8GQL8Serine/threonine-protein phosphatase. (225 aa)
Cdkn1b.SUncharacterized protein. (152 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
skp1Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
psmc2AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
A0A1L8GWC5Uncharacterized protein. (149 aa)
skp1-2Uncharacterized protein; Belongs to the SKP1 family. (221 aa)
Pole4.LCBFD_NFYB_HMF domain-containing protein. (206 aa)
mcm10Mcm10 domain-containing protein. (860 aa)
cdkn2dANK_REP_REGION domain-containing protein. (161 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (720 aa)
A0A1L8H4R2Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa)
A0A1L8H5C2Protein kinase domain-containing protein. (697 aa)
Pola1.SDNA polymerase. (718 aa)
A0A1L8H6B5Uncharacterized protein. (137 aa)
Psmb2.SProteasome subunit beta. (199 aa)
A0A1L8H8T3Uncharacterized protein. (48 aa)
A0A1L8H8T6Uncharacterized protein. (513 aa)
A0A1L8H8U7Transcription factor. (394 aa)
rb1Uncharacterized protein. (899 aa)
Cdk2.SProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
fndc3aUncharacterized protein. (1202 aa)
Ccna1.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (418 aa)
A0A1L8HB55BZIP domain-containing protein. (304 aa)
Cdk4.LProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (348 aa)
A0A1L8HCE8Protein kinase domain-containing protein. (751 aa)
A0A1L8HCZ9Uncharacterized protein. (307 aa)
Rpa1.LReplication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (609 aa)
cdkn1aUncharacterized protein. (261 aa)
tfdp1Transcription factor. (409 aa)
Cdk2.LProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
fndc3a-2Uncharacterized protein. (1200 aa)
Ccna1.LCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (421 aa)
Ccna2.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (415 aa)
kxd1KxDL domain-containing protein. (195 aa)
cdkn2bANK_REP_REGION domain-containing protein. (125 aa)
cks2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
Psme1.SUncharacterized protein. (244 aa)
A0A1L8HPK4Uncharacterized protein. (256 aa)
psmb5Proteasome subunit beta. (257 aa)
Cdc45.SUncharacterized protein. (580 aa)
ubcUncharacterized protein. (533 aa)
Kxd1.LKxDL domain-containing protein. (195 aa)
A0A1L8HX68Ubiquitin-like domain-containing protein. (173 aa)
psmb5-2Proteasome subunit beta. (257 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2285 aa)
cdc45Uncharacterized protein. (567 aa)
Cdk7.LProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
A0A1L8I2J2Uncharacterized protein. (170 aa)
Skp2.LF-box domain-containing protein. (420 aa)
A0A310TNW1Prot_ATP_ID_OB domain-containing protein. (153 aa)
Cdk6.LProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (319 aa)
LOC398610LOC398610 protein. (565 aa)
e2f1-2LOC100036852 protein. (426 aa)
cks2-2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
psmc2-2XMSS1 protein; Belongs to the AAA ATPase family. (433 aa)
ccnd2Cyclin D2; Belongs to the cyclin family. (291 aa)
psmc3-a26S proteasome regulatory subunit 6A-A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). (423 aa)
gmnnGMNN protein. (219 aa)
cdkn2b-2MGC154405 protein. (125 aa)
ccnd2-2MGC132398 protein; Belongs to the cyclin family. (291 aa)
psmb6Proteasome subunit beta. (233 aa)
ccna2MGC130969 protein; Belongs to the cyclin family. (415 aa)
ccnh-ACcnh-A protein; Belongs to the cyclin family. (323 aa)
MGC114992MGC114992 protein; Belongs to the cullin family. (776 aa)
psma1Proteasome subunit alpha type. (261 aa)
Psmb3Proteasome subunit beta. (205 aa)
psmb3Proteasome subunit beta. (205 aa)
psmd10LOC495968 protein. (227 aa)
rpa3LOC495401 protein. (121 aa)
psmf1LOC495127 protein. (263 aa)
psme3Psme3b protein. (254 aa)
psme1LOC494646 protein. (244 aa)
ccndxMGC83328 protein; Belongs to the cyclin family. (290 aa)
psmd7-2MGC84052 protein. (320 aa)
psmb7-2Proteasome subunit beta. (277 aa)
rpa3-2Rpa3-prov protein. (121 aa)
psma6Proteasome subunit alpha type. (246 aa)
cdkn2d-2Ank2-prov protein. (161 aa)
psmd9MGC84770 protein. (208 aa)
psme2MGC84168 protein. (242 aa)
rps27aMGC81889 protein. (156 aa)
psma5Proteasome subunit alpha type. (247 aa)
psmb2Proteasome subunit beta. (199 aa)
psmc5-2MGC80185 protein; Belongs to the AAA ATPase family. (415 aa)
uba52MGC80109 protein. (128 aa)
psme3-2Psme3 protein. (254 aa)
pole3DNA polymerase epsilon p17 subunit. (147 aa)
ubc-2Ubc-prov protein. (609 aa)
psmb7.2Proteasome subunit beta. (279 aa)
psma4Proteasome subunit alpha type. (261 aa)
psmc3Psmc3-b protein; Belongs to the AAA ATPase family. (423 aa)
ppp2r1aPpp2r1a-prov protein. (589 aa)
psmd14Psmd14-prov protein. (310 aa)
psmd6P44s10-prov protein. (389 aa)
psmb1Proteasome subunit beta. (239 aa)
ppp2r1bPpp2r1b protein. (589 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa)
psmd9-2MGC53232 protein. (213 aa)
psma3Proteasome subunit alpha type. (255 aa)
ccnd1Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
cdknxCyclin-dependent kinase inhibitor p28. (209 aa)
psmb8Proteasome subunit beta. (271 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
e2f3-2Transcription factor E2F. (429 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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