42 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8FZI3	Uncharacterized protein. (174 aa)
	LOC100498450.S	Methyltransf_11 domain-containing protein. (269 aa)
	A0A1L8EPJ9	Methyltransf_11 domain-containing protein. (270 aa)
	A0A1L8EX65	Methyltransf_11 domain-containing protein. (270 aa)
	A0A1L8F2I8	Uncharacterized protein. (1067 aa)
	A0A1L8F6T4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
	A0A1L8F791	Uncharacterized protein. (1177 aa)
	A0A1L8FG79	Uncharacterized protein. (889 aa)
	gsk3a	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (424 aa)
	A0A1L8FJW6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (431 aa)
	A0A1L8FLR1	Uncharacterized protein. (661 aa)
	dvl1	Uncharacterized protein. (606 aa)
	A0A1L8FN20	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
	Frat1.S	Uncharacterized protein. (168 aa)
	Hmgxb3.L	HMG box domain-containing protein. (1247 aa)
	A0A1L8GXA3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (261 aa)
	csnk1a1-2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (337 aa)
	A0A1L8H4V1	Uncharacterized protein. (678 aa)
	A0A1L8H5Q6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	A0A1L8HBT3	Uncharacterized protein. (28 aa)
	A0A1L8HBT4	Protein kinase domain-containing protein. (64 aa)
	A0A1L8HBY8	Protein kinase domain-containing protein. (298 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Xwnt-8b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	cav1a	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	ppp2r1a	Ppp2r1a-prov protein. (589 aa)
	ctnnb1-2	Ctnnb1-prov protein. (781 aa)
	ppp2r1b	Ppp2r1b protein. (589 aa)
	Cav-3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
	A0A1L8G423	Uncharacterized protein. (711 aa)
	Dvl3.L	Uncharacterized protein. (745 aa)
	A0A1L8GCZ1	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (491 aa)
	A0A1L8GJK4	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (456 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	A0A1L8GPB5	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (141 aa)
	cav3.1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
	A0A1L8GQT6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	csnk1a1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
	A0A1L8GVI0	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F2I8	A0A1L8FN20	A0A1L8F2I8	A0A1L8FN20	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.630
A0A1L8F2I8	A0A1L8GQT6	A0A1L8F2I8	A0A1L8GQT6	Uncharacterized protein.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.551
A0A1L8F2I8	A0A1L8H5Q6	A0A1L8F2I8	A0A1L8H5Q6	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.630
A0A1L8F2I8	A0A1L8HBT3	A0A1L8F2I8	A0A1L8HBT3	Uncharacterized protein.	Uncharacterized protein.	0.630
A0A1L8F2I8	A0A1L8HBT4	A0A1L8F2I8	A0A1L8HBT4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.630
A0A1L8F2I8	A0A1L8HBY8	A0A1L8F2I8	A0A1L8HBY8	Uncharacterized protein.	Protein kinase domain-containing protein.	0.630
A0A1L8F2I8	Lrp5.L	A0A1L8F2I8	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.496
A0A1L8F2I8	Wnt1.L	A0A1L8F2I8	A0A1L8HHR8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.435
A0A1L8F2I8	csnk1a1	A0A1L8F2I8	A0A1L8GV61	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.742
A0A1L8F2I8	csnk1a1-2	A0A1L8F2I8	A0A1L8GXP6	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.742
A0A1L8F2I8	ctnnb1	A0A1L8F2I8	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.895
A0A1L8F2I8	ctnnb1-2	A0A1L8F2I8	Q7ZX35	Uncharacterized protein.	Ctnnb1-prov protein.	0.882
A0A1L8F2I8	gsk3a	A0A1L8F2I8	A0A1L8FGT4	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.630
A0A1L8F2I8	wnt1	A0A1L8F2I8	A0A1L8H9S8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.435
A0A1L8F6T4	A0A1L8GQT6	A0A1L8F6T4	A0A1L8GQT6	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.808
A0A1L8F6T4	Lrp5.L	A0A1L8F6T4	A0A1L8GJX4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.736
A0A1L8F6T4	ctnnb1	A0A1L8F6T4	Q63ZT4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Beta-catenin protein.	0.802
A0A1L8F6T4	ctnnb1-2	A0A1L8F6T4	Q7ZX35	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Ctnnb1-prov protein.	0.443
A0A1L8F791	A0A1L8FN20	A0A1L8F791	A0A1L8FN20	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.630
A0A1L8F791	A0A1L8GQT6	A0A1L8F791	A0A1L8GQT6	Uncharacterized protein.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.551