69 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8H2P8	Uncharacterized protein. (217 aa)
	grb2	Uncharacterized protein. (229 aa)
	grb2-2	Uncharacterized protein. (229 aa)
	Rapgef1.L	N-terminal Ras-GEF domain-containing protein. (157 aa)
	A0A1L8F6Y5	SH2 domain-containing protein. (866 aa)
	il2rg	Fibronectin type-III domain-containing protein. (350 aa)
	ptpn6	Uncharacterized protein. (687 aa)
	A0A1L8FG16	Uncharacterized protein. (559 aa)
	lyn	Tyrosine-protein kinase. (508 aa)
	A0A1L8FTA7	Ubiquitin-like domain-containing protein. (105 aa)
	Ywhaz.L	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
	lyn-2	Tyrosine-protein kinase. (508 aa)
	Ywhaz.S	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
	sos1	Uncharacterized protein. (1325 aa)
	A0A1L8G3Z7	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	inpp5d	SH2 domain-containing protein. (1099 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	sos1-2	Uncharacterized protein. (1325 aa)
	A0A1L8GA65	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1009 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	Inpp5d.L	SH2 domain-containing protein. (1111 aa)
	A0A1L8GH68	Fibronectin type-III domain-containing protein. (509 aa)
	csf2rb	Uncharacterized protein. (765 aa)
	il5ra	IL6Ra-bind domain-containing protein. (427 aa)
	A0A1L8GNZ3	Uncharacterized protein. (777 aa)
	A0A1L8GP20	Fibronectin type-III domain-containing protein. (503 aa)
	Il5ra.L	IL6Ra-bind domain-containing protein. (426 aa)
	A0A1L8GVS1	Uncharacterized protein. (404 aa)
	gab2	PH domain-containing protein. (673 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	Crk.L	Uncharacterized protein. (297 aa)
	A0A1L8HI41	Uncharacterized protein. (330 aa)
	A0A1L8HI45	Uncharacterized protein. (363 aa)
	LOC100496837.L	Uncharacterized protein. (360 aa)
	A0A1L8HI67	Uncharacterized protein. (349 aa)
	A0A1L8HIC2	Uncharacterized protein. (349 aa)
	gab2-2	PH domain-containing protein. (677 aa)
	inppl1	Uncharacterized protein. (1268 aa)
	A0A1L8HNI8	Uncharacterized protein. (721 aa)
	Syk.S	Tyrosine-protein kinase. (632 aa)
	ubc	Uncharacterized protein. (533 aa)
	A0A1L8HWT4	Uncharacterized protein. (717 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	Jak3.L	Tyrosine-protein kinase. (1118 aa)
	jak2	Tyrosine-protein kinase. (1129 aa)
	syk	Tyrosine-protein kinase. (605 aa)
	A0A1L8I158	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
	Jak2.S	Tyrosine-protein kinase. (1088 aa)
	PIK3R1	Phosphoinositide-3-kinase. (722 aa)
	ptpn6-2	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (587 aa)
	pik3r3	MGC84470 protein. (461 aa)
	crkl	MGC84382 protein. (302 aa)
	pik3r2	Pik3r2-prov protein. (457 aa)
	rps27a	MGC81889 protein. (156 aa)
	rapgef1	MGC80732 protein. (1035 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	pik3r1	MGC80357 protein. (722 aa)
	uba52	MGC80109 protein. (128 aa)
	crkl-2	MGC81407 protein. (302 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	A0A1L8H2R5	Uncharacterized protein. (441 aa)
	A0A1L8H4P2	Fibronectin type-III domain-containing protein. (318 aa)
	A0A1L8H4R3	Uncharacterized protein. (417 aa)
	crk	Uncharacterized protein. (297 aa)
	A0A1L8H9W0	Uncharacterized protein. (359 aa)
	A0A1L8H9Z4	Uncharacterized protein. (263 aa)
	A0A1L8HA21	Uncharacterized protein. (331 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F6Y5	A0A1L8FG16	A0A1L8F6Y5	A0A1L8FG16	SH2 domain-containing protein.	Uncharacterized protein.	0.718
A0A1L8F6Y5	A0A1L8G3Z7	A0A1L8F6Y5	A0A1L8G3Z7	SH2 domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.737
A0A1L8F6Y5	A0A1L8GNZ3	A0A1L8F6Y5	A0A1L8GNZ3	SH2 domain-containing protein.	Uncharacterized protein.	0.654
A0A1L8F6Y5	A0A1L8GVS1	A0A1L8F6Y5	A0A1L8GVS1	SH2 domain-containing protein.	Uncharacterized protein.	0.654
A0A1L8F6Y5	A0A1L8H2P8	A0A1L8F6Y5	A0A1L8H2P8	SH2 domain-containing protein.	Uncharacterized protein.	0.654
A0A1L8F6Y5	A0A1L8H2R5	A0A1L8F6Y5	A0A1L8H2R5	SH2 domain-containing protein.	Uncharacterized protein.	0.654
A0A1L8F6Y5	A0A1L8H4R3	A0A1L8F6Y5	A0A1L8H4R3	SH2 domain-containing protein.	Uncharacterized protein.	0.655
A0A1L8F6Y5	A0A1L8HNI8	A0A1L8F6Y5	A0A1L8HNI8	SH2 domain-containing protein.	Uncharacterized protein.	0.820
A0A1L8F6Y5	A0A1L8HWT4	A0A1L8F6Y5	A0A1L8HWT4	SH2 domain-containing protein.	Uncharacterized protein.	0.820
A0A1L8F6Y5	A0A1L8I158	A0A1L8F6Y5	A0A1L8I158	SH2 domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.718
A0A1L8F6Y5	Inpp5d.L	A0A1L8F6Y5	A0A1L8GB96	SH2 domain-containing protein.	SH2 domain-containing protein.	0.479
A0A1L8F6Y5	Jak2.S	A0A1L8F6Y5	A0A310U8T2	SH2 domain-containing protein.	Tyrosine-protein kinase.	0.488
A0A1L8F6Y5	Jak3.L	A0A1L8F6Y5	A0A1L8HXG0	SH2 domain-containing protein.	Tyrosine-protein kinase.	0.488
A0A1L8F6Y5	PIK3R1	A0A1L8F6Y5	B7ZRD8	SH2 domain-containing protein.	Phosphoinositide-3-kinase.	0.820
A0A1L8F6Y5	Ptpn11.S	A0A1L8F6Y5	Q92124	SH2 domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.718
A0A1L8F6Y5	csf2rb	A0A1L8F6Y5	A0A1L8GH84	SH2 domain-containing protein.	Uncharacterized protein.	0.654
A0A1L8F6Y5	grb2	A0A1L8F6Y5	A0A1L8EMZ6	SH2 domain-containing protein.	Uncharacterized protein.	0.785
A0A1L8F6Y5	grb2-2	A0A1L8F6Y5	A0A1L8EUF2	SH2 domain-containing protein.	Uncharacterized protein.	0.785
A0A1L8F6Y5	inpp5d	A0A1L8F6Y5	A0A1L8G4S3	SH2 domain-containing protein.	SH2 domain-containing protein.	0.477
A0A1L8F6Y5	inppl1	A0A1L8F6Y5	A0A1L8HJJ3	SH2 domain-containing protein.	Uncharacterized protein.	0.944