54 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	polh	Polh-prov protein. (684 aa)
	rpa3-2	Rpa3-prov protein. (121 aa)
	rpa3	LOC495401 protein. (121 aa)
	rfc3	MGC115007 protein. (356 aa)
	usp31	USP domain-containing protein; Belongs to the peptidase C19 family. (1240 aa)
	trim25	Uncharacterized protein. (622 aa)
	A0A1L8ENC4	AAA domain-containing protein. (1731 aa)
	A0A1L8EN99	Ubiquitin carboxyl-terminal hydrolase. (989 aa)
	A0A1L8EKD3	Uncharacterized protein. (183 aa)
	pole3	DNA polymerase epsilon p17 subunit. (147 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	rps27a	MGC81889 protein. (156 aa)
	rcbtb2	Chc1l-prov protein. (526 aa)
	uba52	MGC80109 protein. (128 aa)
	rfc5	Rfc5-prov protein. (335 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	rfc4	Replication factor C p37 subunit. (363 aa)
	polk	UmuC domain-containing protein. (862 aa)
	pole	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2285 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	Kxd1.L	KxDL domain-containing protein. (195 aa)
	rfc1	Replication factor C subunit 1. (1147 aa)
	poli	UmuC domain-containing protein. (737 aa)
	Rfc5.S	AAA domain-containing protein. (335 aa)
	ubc	Uncharacterized protein. (533 aa)
	kxd1	KxDL domain-containing protein. (195 aa)
	A0A1L8HK04	Uncharacterized protein. (779 aa)
	Rcbtb1.L	BTB domain-containing protein. (600 aa)
	rev1-2	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1237 aa)
	Rfc2.L	AAA domain-containing protein. (359 aa)
	Rpa1.L	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (609 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	Rcbtb1.S	BTB domain-containing protein. (600 aa)
	rev1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1230 aa)
	A0A1L8H4R2	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa)
	pold2	Uncharacterized protein. (463 aa)
	pclaf-2	PAF domain-containing protein. (128 aa)
	Pole4.L	CBFD_NFYB_HMF domain-containing protein. (206 aa)
	pclaf	PAF domain-containing protein. (123 aa)
	A0A1L8GS29	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (268 aa)
	usp10-2	Ubiquitin carboxyl-terminal hydrolase. (805 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (805 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	A0A1L8FTA7	Ubiquitin-like domain-containing protein. (105 aa)
	Pold1.L	DNA polymerase. (1109 aa)
	Pole2.L	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (569 aa)
	A0A1L8F0R3	Uncharacterized protein. (136 aa)
	Meiob.L	Uncharacterized protein. (470 aa)
	usp31-2	USP domain-containing protein; Belongs to the peptidase C19 family. (1244 aa)
	trim25-2	Uncharacterized protein. (661 aa)
	A0A1L8EV25	Uncharacterized protein. (567 aa)
	atad5	AAA domain-containing protein. (1740 aa)
	A0A1L8EUT3	USP domain-containing protein; Belongs to the peptidase C19 family. (1162 aa)
	trim65	Uncharacterized protein. (536 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EKD3	A0A1L8FTA7	A0A1L8EKD3	A0A1L8FTA7	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.421
A0A1L8EKD3	A0A1L8G5V1	A0A1L8EKD3	A0A1L8G5V1	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.507
A0A1L8EKD3	A0A1L8GS29	A0A1L8EKD3	A0A1L8GS29	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.508
A0A1L8EKD3	A0A1L8HCZ9	A0A1L8EKD3	A0A1L8HCZ9	Uncharacterized protein.	Uncharacterized protein.	0.564
A0A1L8EKD3	A0A1L8HX68	A0A1L8EKD3	A0A1L8HX68	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.421
A0A1L8EKD3	Pold1.L	A0A1L8EKD3	A0A1L8FNR6	Uncharacterized protein.	DNA polymerase.	0.401
A0A1L8EKD3	Pole4.L	A0A1L8EKD3	A0A1L8GXM8	Uncharacterized protein.	CBFD_NFYB_HMF domain-containing protein.	0.408
A0A1L8EKD3	Rfc2.L	A0A1L8EKD3	A0A1L8HGA4	Uncharacterized protein.	AAA domain-containing protein.	0.545
A0A1L8EKD3	Rfc5.S	A0A1L8EKD3	A0A1L8HQV3	Uncharacterized protein.	AAA domain-containing protein.	0.457
A0A1L8EKD3	pcna	A0A1L8EKD3	Q9I893	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.519
A0A1L8EKD3	pole	A0A1L8EKD3	A0A1L8HZP3	Uncharacterized protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.401
A0A1L8EKD3	polh	A0A1L8EKD3	Q6DCL9	Uncharacterized protein.	Polh-prov protein.	0.582
A0A1L8EKD3	poli	A0A1L8EKD3	A0A1L8HRY0	Uncharacterized protein.	UmuC domain-containing protein.	0.494
A0A1L8EKD3	polk	A0A1L8EKD3	A0A1L8I207	Uncharacterized protein.	UmuC domain-containing protein.	0.553
A0A1L8EKD3	rev1	A0A1L8EKD3	A0A1L8H8Q0	Uncharacterized protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.476
A0A1L8EKD3	rev1-2	A0A1L8EKD3	A0A1L8HGZ7	Uncharacterized protein.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.476
A0A1L8EKD3	rfc1	A0A1L8EKD3	A0A1L8HTJ6	Uncharacterized protein.	Replication factor C subunit 1.	0.540
A0A1L8EKD3	rfc3	A0A1L8EKD3	Q4QQP4	Uncharacterized protein.	MGC115007 protein.	0.544
A0A1L8EKD3	rfc4	A0A1L8EKD3	Q76LD2	Uncharacterized protein.	Replication factor C p37 subunit.	0.546
A0A1L8EKD3	rfc5	A0A1L8EKD3	Q7ZTM5	Uncharacterized protein.	Rfc5-prov protein.	0.457