STRINGSTRING
cdca7 cdca7 A0A1L8EPM6 A0A1L8EPM6 Brca1.L Brca1.L bard1 bard1 rmi2 rmi2 Meiob.L Meiob.L top3a top3a exd2 exd2 Exo1.S Exo1.S exd2-2 exd2-2 rad51 rad51 Dna2.S Dna2.S ercc1 ercc1 ankrd12 ankrd12 rbbp8 rbbp8 topbp1 topbp1 ankrd12-2 ankrd12-2 Rbbp8.L Rbbp8.L Nbn.L Nbn.L Atr.L Atr.L ankrd11 ankrd11 atrip atrip Rad26 Rad26 Rad52.S Rad52.S Rhno1.S Rhno1.S blm blm rad50 rad50 A0A1L8GWA8 A0A1L8GWA8 rad50-2 rad50-2 A0A1L8H1D5 A0A1L8H1D5 A0A1L8H4R2 A0A1L8H4R2 tdrd3 tdrd3 Rcbtb1.S Rcbtb1.S Recql4.L Recql4.L Rpa1.L Rpa1.L Rfc2.L Rfc2.L Tdrd3.L Tdrd3.L Rcbtb1.L Rcbtb1.L mre11 mre11 A0A1L8HPD7 A0A1L8HPD7 Rfc5.S Rfc5.S A0A1L8HRA7 A0A1L8HRA7 A0A1L8HRF5 A0A1L8HRF5 wrn wrn A0A1L8HYF4 A0A1L8HYF4 rad9b rad9b slf1 slf1 Rad17.L Rad17.L rad1 rad1 rfc3 rfc3 rpa3 rpa3 rpa3-2 rpa3-2 rfc4 rfc4 rfc5 rfc5 rcbtb2 rcbtb2 rad9a rad9a Hus1 Hus1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdca7zf-4CXXC_R1 domain-containing protein. (431 aa)
A0A1L8EPM6ANK_REP_REGION domain-containing protein. (400 aa)
Brca1.LUncharacterized protein. (1582 aa)
bard1Uncharacterized protein. (839 aa)
rmi2Uncharacterized protein. (152 aa)
Meiob.LUncharacterized protein. (470 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1022 aa)
exd23'-5' exonuclease domain-containing protein. (639 aa)
Exo1.SUncharacterized protein. (734 aa)
exd2-23'-5' exonuclease domain-containing protein. (642 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (336 aa)
Dna2.SUncharacterized protein. (1053 aa)
ercc1Uncharacterized protein. (297 aa)
ankrd12ANK_REP_REGION domain-containing protein. (1985 aa)
rbbp8Uncharacterized protein. (846 aa)
topbp1Uncharacterized protein. (1573 aa)
ankrd12-2ANK_REP_REGION domain-containing protein. (1961 aa)
Rbbp8.LUncharacterized protein. (856 aa)
Nbn.LNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (762 aa)
Atr.LUncharacterized protein; Belongs to the PI3/PI4-kinase family. (2654 aa)
ankrd11ANK_REP_REGION domain-containing protein. (2741 aa)
atripUncharacterized protein. (801 aa)
Rad26Uncharacterized protein. (798 aa)
Rad52.SUncharacterized protein. (429 aa)
Rhno1.SUncharacterized protein. (252 aa)
blmUncharacterized protein. (1368 aa)
rad50Zinc-hook domain-containing protein. (1311 aa)
A0A1L8GWA8Uncharacterized protein. (209 aa)
rad50-2Zinc-hook domain-containing protein. (1312 aa)
A0A1L8H1D5Uncharacterized protein. (1367 aa)
A0A1L8H4R2Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa)
tdrd3Uncharacterized protein. (742 aa)
Rcbtb1.SBTB domain-containing protein. (600 aa)
Recql4.LUncharacterized protein. (1504 aa)
Rpa1.LReplication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (609 aa)
Rfc2.LAAA domain-containing protein. (359 aa)
Tdrd3.LUncharacterized protein. (775 aa)
Rcbtb1.LBTB domain-containing protein. (600 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (711 aa)
A0A1L8HPD7Uncharacterized protein. (341 aa)
Rfc5.SAAA domain-containing protein. (335 aa)
A0A1L8HRA7Uncharacterized protein. (177 aa)
A0A1L8HRF5Uncharacterized protein. (426 aa)
wrnUncharacterized protein. (1434 aa)
A0A1L8HYF4DUF1767 domain-containing protein. (512 aa)
rad9bCell cycle checkpoint control protein; Belongs to the rad9 family. (483 aa)
slf1ANK_REP_REGION domain-containing protein. (904 aa)
Rad17.LUncharacterized protein. (674 aa)
rad1Uncharacterized protein. (283 aa)
rfc3MGC115007 protein. (356 aa)
rpa3LOC495401 protein. (121 aa)
rpa3-2Rpa3-prov protein. (121 aa)
rfc4Replication factor C p37 subunit. (363 aa)
rfc5Rfc5-prov protein. (335 aa)
rcbtb2Chc1l-prov protein. (526 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
Hus1Checkpoint protein; Belongs to the HUS1 family. (282 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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