STRINGSTRING
Xrcc2.S Xrcc2.S pcna pcna rcbtb2 rcbtb2 rfc5 rfc5 ubc-2 ubc-2 rfc4 rfc4 pole3 pole3 uba52 uba52 A0A1L8EPM6 A0A1L8EPM6 A0A1L8EQR1 A0A1L8EQR1 Brca1.L Brca1.L Eme1.L Eme1.L bard1 bard1 rmi2 rmi2 palb2 palb2 eme2 eme2 slx4 slx4 Meiob.L Meiob.L top3a top3a exd2 exd2 A0A1L8F0R3 A0A1L8F0R3 Exo1.S Exo1.S rad51ap1 rad51ap1 Pole2.L Pole2.L xrcc3 xrcc3 exd2-2 exd2-2 rad51 rad51 Dna2.S Dna2.S chek1 chek1 chek1-2 chek1-2 Pold1.L Pold1.L A0A1L8FQI2 A0A1L8FQI2 ankrd12 ankrd12 rbbp8 rbbp8 A0A1L8FTA7 A0A1L8FTA7 A0A1L8FV52 A0A1L8FV52 ankrd12-2 ankrd12-2 Rbbp8.L Rbbp8.L Spidr.L Spidr.L Nbn.L Nbn.L A0A1L8G5V1 A0A1L8G5V1 A0A1L8GBG8 A0A1L8GBG8 ankrd11 ankrd11 mus81 mus81 A0A1L8GS29 A0A1L8GS29 blm blm rad50 rad50 rad50-2 rad50-2 Pole4.L Pole4.L A0A1L8H1D5 A0A1L8H1D5 pold2 pold2 A0A1L8H4R2 A0A1L8H4R2 A0A1L8H854 A0A1L8H854 tdrd3 tdrd3 Rcbtb1.S Rcbtb1.S Recql4.L Recql4.L A0A1L8HCZ9 A0A1L8HCZ9 Rpa1.L Rpa1.L A0A1L8HG81 A0A1L8HG81 Rfc2.L Rfc2.L Tdrd3.L Tdrd3.L Rcbtb1.L Rcbtb1.L brca2 brca2 mre11 mre11 A0A1L8HK04 A0A1L8HK04 kxd1 kxd1 A0A1L8HPD7 A0A1L8HPD7 ubc ubc Rfc5.S Rfc5.S A0A1L8HRF5 A0A1L8HRF5 rfc1 rfc1 rps27a rps27a rad51d rad51d polh polh wrn wrn rpa3-2 rpa3-2 rpa3 rpa3 rfc3 rfc3 polk polk pole pole A0A1L8HYF4 A0A1L8HYF4 A0A1L8HX68 A0A1L8HX68 Kxd1.L Kxd1.L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Xrcc2.SRECA_2 domain-containing protein. (223 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
rcbtb2Chc1l-prov protein. (526 aa)
rfc5Rfc5-prov protein. (335 aa)
ubc-2Ubc-prov protein. (609 aa)
rfc4Replication factor C p37 subunit. (363 aa)
pole3DNA polymerase epsilon p17 subunit. (147 aa)
uba52MGC80109 protein. (128 aa)
A0A1L8EPM6ANK_REP_REGION domain-containing protein. (400 aa)
A0A1L8EQR1PALB2_WD40 domain-containing protein. (1345 aa)
Brca1.LUncharacterized protein. (1582 aa)
Eme1.LERCC4 domain-containing protein. (411 aa)
bard1Uncharacterized protein. (839 aa)
rmi2Uncharacterized protein. (152 aa)
palb2PALB2_WD40 domain-containing protein. (1427 aa)
eme2ERCC4 domain-containing protein. (500 aa)
slx4BTB domain-containing protein. (1773 aa)
Meiob.LUncharacterized protein. (470 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1022 aa)
exd23'-5' exonuclease domain-containing protein. (639 aa)
A0A1L8F0R3Uncharacterized protein. (136 aa)
Exo1.SUncharacterized protein. (734 aa)
rad51ap1RAD51_interact domain-containing protein. (319 aa)
Pole2.LDNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (569 aa)
xrcc3RECA_2 domain-containing protein. (360 aa)
exd2-23'-5' exonuclease domain-containing protein. (642 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (336 aa)
Dna2.SUncharacterized protein. (1053 aa)
chek1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
chek1-2Protein kinase domain-containing protein. (510 aa)
Pold1.LDNA polymerase. (1109 aa)
A0A1L8FQI2Uncharacterized protein. (76 aa)
ankrd12ANK_REP_REGION domain-containing protein. (1985 aa)
rbbp8Uncharacterized protein. (846 aa)
A0A1L8FTA7Ubiquitin-like domain-containing protein. (105 aa)
A0A1L8FV52RECA_2 domain-containing protein. (213 aa)
ankrd12-2ANK_REP_REGION domain-containing protein. (1961 aa)
Rbbp8.LUncharacterized protein. (856 aa)
Spidr.LUncharacterized protein. (866 aa)
Nbn.LNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (762 aa)
A0A1L8G5V1Ubiquitin-like domain-containing protein. (156 aa)
A0A1L8GBG8Uncharacterized protein. (1054 aa)
ankrd11ANK_REP_REGION domain-containing protein. (2741 aa)
mus81ERCC4 domain-containing protein. (613 aa)
A0A1L8GS29Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (268 aa)
blmUncharacterized protein. (1368 aa)
rad50Zinc-hook domain-containing protein. (1311 aa)
rad50-2Zinc-hook domain-containing protein. (1312 aa)
Pole4.LCBFD_NFYB_HMF domain-containing protein. (206 aa)
A0A1L8H1D5Uncharacterized protein. (1367 aa)
pold2Uncharacterized protein. (463 aa)
A0A1L8H4R2Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa)
A0A1L8H854Uncharacterized protein. (98 aa)
tdrd3Uncharacterized protein. (742 aa)
Rcbtb1.SBTB domain-containing protein. (600 aa)
Recql4.LUncharacterized protein. (1504 aa)
A0A1L8HCZ9Uncharacterized protein. (307 aa)
Rpa1.LReplication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (609 aa)
A0A1L8HG81RECA_2 domain-containing protein. (375 aa)
Rfc2.LAAA domain-containing protein. (359 aa)
Tdrd3.LUncharacterized protein. (775 aa)
Rcbtb1.LBTB domain-containing protein. (600 aa)
brca2Tower domain-containing protein. (3177 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (711 aa)
A0A1L8HK04Uncharacterized protein. (779 aa)
kxd1KxDL domain-containing protein. (195 aa)
A0A1L8HPD7Uncharacterized protein. (341 aa)
ubcUncharacterized protein. (533 aa)
Rfc5.SAAA domain-containing protein. (335 aa)
A0A1L8HRF5Uncharacterized protein. (426 aa)
rfc1Replication factor C subunit 1. (1147 aa)
rps27aMGC81889 protein. (156 aa)
rad51dMGC82048 protein. (324 aa)
polhPolh-prov protein. (684 aa)
wrnUncharacterized protein. (1434 aa)
rpa3-2Rpa3-prov protein. (121 aa)
rpa3LOC495401 protein. (121 aa)
rfc3MGC115007 protein. (356 aa)
polkUmuC domain-containing protein. (862 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2285 aa)
A0A1L8HYF4DUF1767 domain-containing protein. (512 aa)
A0A1L8HX68Ubiquitin-like domain-containing protein. (173 aa)
Kxd1.LKxDL domain-containing protein. (195 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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