57 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100049093	LOC100049093 protein. (452 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1011 aa)
	cops7b	MGC114836 protein. (264 aa)
	cops8	Cops8-prov protein. (193 aa)
	rps27a	MGC81889 protein. (156 aa)
	uba52	MGC80109 protein. (128 aa)
	ruvbl1-2	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	mcrs1	Mcrs1-prov protein. (453 aa)
	cetn3	Cetn3 protein. (167 aa)
	ruvbl1	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
	parp3	Poly [ADP-ribose] polymerase. (547 aa)
	Rbx1.L	RING-type domain-containing protein. (168 aa)
	ddb2	WD_REPEATS_REGION domain-containing protein. (489 aa)
	rbx1	RING-type domain-containing protein. (120 aa)
	A0A1L8GDW6	WD_REPEATS_REGION domain-containing protein. (458 aa)
	ddb1	CPSF_A domain-containing protein. (1140 aa)
	Vwa5b2.L	VIT domain-containing protein. (1289 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	Cops5.L	MPN domain-containing protein. (143 aa)
	A0A1L8FTA7	Ubiquitin-like domain-containing protein. (105 aa)
	Cops5.S	MPN domain-containing protein. (286 aa)
	A0A1L8FMY4	Uncharacterized protein. (267 aa)
	A0A1L8FL85	NFRKB_winged domain-containing protein. (1263 aa)
	A0A1L8FGQ7	Uncharacterized protein. (250 aa)
	ino80	Uncharacterized protein. (1539 aa)
	Yy1.L	Uncharacterized protein. (392 aa)
	A0A1L8F746	CULLIN_2 domain-containing protein; Belongs to the cullin family. (848 aa)
	Cul4b.S	CULLIN_2 domain-containing protein; Belongs to the cullin family. (866 aa)
	Yy1.S	Uncharacterized protein. (372 aa)
	cops3-2	PCI domain-containing protein. (423 aa)
	Ino80d.L	Uncharacterized protein. (1025 aa)
	gps1	PCI domain-containing protein. (487 aa)
	cops3	PCI domain-containing protein. (423 aa)
	ino80d	Uncharacterized protein. (1025 aa)
	Cops8.S	PCI domain-containing protein. (195 aa)
	actr5	Uncharacterized protein; Belongs to the actin family. (590 aa)
	xpc	Uncharacterized protein. (1062 aa)
	Wdr76.S	WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (584 aa)
	A0A1L8GSU3	PCI domain-containing protein. (443 aa)
	Rpap3.L	TPR_REGION domain-containing protein. (660 aa)
	Cops2.L	PCI domain-containing protein. (457 aa)
	cul4a	CULLIN_2 domain-containing protein; Belongs to the cullin family. (753 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	A0A1L8HH08	CULLIN_2 domain-containing protein; Belongs to the cullin family. (753 aa)
	Ino80b.S	PAPA-1 domain-containing protein. (321 aa)
	Wbp1.S	Uncharacterized protein. (306 aa)
	kxd1	KxDL domain-containing protein. (195 aa)
	Rad23b.S	Uncharacterized protein. (412 aa)
	parp2	Poly [ADP-ribose] polymerase. (742 aa)
	ubc	Uncharacterized protein. (533 aa)
	Cetn3.S	Uncharacterized protein. (199 aa)
	Kxd1.L	KxDL domain-containing protein. (195 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	Rad23b.L	Uncharacterized protein. (419 aa)
	parp2-2	Poly [ADP-ribose] polymerase. (680 aa)
	cops4	Cops4 protein. (406 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F746	A0A1L8G5V1	A0A1L8F746	A0A1L8G5V1	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.643
A0A1L8F746	A0A1L8GDW6	A0A1L8F746	A0A1L8GDW6	CULLIN_2 domain-containing protein; Belongs to the cullin family.	WD_REPEATS_REGION domain-containing protein.	0.813
A0A1L8F746	A0A1L8GSU3	A0A1L8F746	A0A1L8GSU3	CULLIN_2 domain-containing protein; Belongs to the cullin family.	PCI domain-containing protein.	0.794
A0A1L8F746	A0A1L8HCZ9	A0A1L8F746	A0A1L8HCZ9	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.584
A0A1L8F746	Cetn3.S	A0A1L8F746	A0A1L8HR81	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.492
A0A1L8F746	Cops2.L	A0A1L8F746	A0A1L8H0N4	CULLIN_2 domain-containing protein; Belongs to the cullin family.	PCI domain-containing protein.	0.794
A0A1L8F746	Cops5.L	A0A1L8F746	A0A1L8FZ72	CULLIN_2 domain-containing protein; Belongs to the cullin family.	MPN domain-containing protein.	0.849
A0A1L8F746	Cops5.S	A0A1L8F746	A0A1L8FTA0	CULLIN_2 domain-containing protein; Belongs to the cullin family.	MPN domain-containing protein.	0.849
A0A1L8F746	Cops8.S	A0A1L8F746	A0A1L8EPG2	CULLIN_2 domain-containing protein; Belongs to the cullin family.	PCI domain-containing protein.	0.812
A0A1L8F746	Ino80b.S	A0A1L8F746	A0A1L8HK30	CULLIN_2 domain-containing protein; Belongs to the cullin family.	PAPA-1 domain-containing protein.	0.443
A0A1L8F746	Rad23b.L	A0A1L8F746	A0A1L8HXY0	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.698
A0A1L8F746	Rad23b.S	A0A1L8F746	A0A1L8HNW9	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Uncharacterized protein.	0.698
A0A1L8F746	Rbx1.L	A0A1L8F746	A0A1L8GNG7	CULLIN_2 domain-containing protein; Belongs to the cullin family.	RING-type domain-containing protein.	0.898
A0A1L8F746	Vwa5b2.L	A0A1L8F746	A0A1L8GA33	CULLIN_2 domain-containing protein; Belongs to the cullin family.	VIT domain-containing protein.	0.437
A0A1L8F746	Wdr76.S	A0A1L8F746	A0A1L8GS95	CULLIN_2 domain-containing protein; Belongs to the cullin family.	WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.	0.753
A0A1L8F746	cetn3	A0A1L8F746	Q9DEZ4	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Cetn3 protein.	0.492
A0A1L8F746	cops3	A0A1L8F746	A0A1L8EQY2	CULLIN_2 domain-containing protein; Belongs to the cullin family.	PCI domain-containing protein.	0.777
A0A1L8F746	cops3-2	A0A1L8F746	A0A1L8EYN7	CULLIN_2 domain-containing protein; Belongs to the cullin family.	PCI domain-containing protein.	0.777
A0A1L8F746	cops4	A0A1L8F746	A2RRW9	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Cops4 protein.	0.926
A0A1L8F746	cops7b	A0A1L8F746	Q498I8	CULLIN_2 domain-containing protein; Belongs to the cullin family.	MGC114836 protein.	0.881