46 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8H4R2	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa)
	proser1	Uncharacterized protein. (904 aa)
	A0A1L8HCW5	Uncharacterized protein. (858 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	Rpa1.L	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (609 aa)
	dclre1b	Lactamase_B domain-containing protein. (519 aa)
	proser1-2	Uncharacterized protein. (889 aa)
	kxd1	KxDL domain-containing protein. (195 aa)
	ubc	Uncharacterized protein. (533 aa)
	fancg	TPR_REGION domain-containing protein. (640 aa)
	Kxd1.L	KxDL domain-containing protein. (195 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	fancc	Uncharacterized protein. (551 aa)
	Fanca.L	Fanconi_A_N domain-containing protein. (1423 aa)
	rpa3	LOC495401 protein. (121 aa)
	rpa3-2	Rpa3-prov protein. (121 aa)
	rps27a	MGC81889 protein. (156 aa)
	uba52	MGC80109 protein. (128 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	nutf2	Nutf2-prov protein. (127 aa)
	Eme1.L	ERCC4 domain-containing protein. (411 aa)
	eme2	ERCC4 domain-containing protein. (500 aa)
	slx4	BTB domain-containing protein. (1773 aa)
	Meiob.L	Uncharacterized protein. (470 aa)
	fancf	Uncharacterized protein. (348 aa)
	Fancm.L	Uncharacterized protein. (2165 aa)
	A0A1L8FG45	Uncharacterized protein. (297 aa)
	Dclre1a.L	DRMBL domain-containing protein. (932 aa)
	ercc1	Uncharacterized protein. (297 aa)
	A0A1L8FQI3	WD_REPEATS_REGION domain-containing protein. (644 aa)
	A0A1L8FTA7	Ubiquitin-like domain-containing protein. (105 aa)
	A0A1L8FV65	WD_REPEATS_REGION domain-containing protein. (991 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	Fancl.L	RING-type domain-containing protein. (361 aa)
	Atr.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2654 aa)
	A0A1L8GE59	NTF2 domain-containing protein. (230 aa)
	usp1	Ubiquitin carboxyl-terminal hydrolase. (766 aa)
	atrip	Uncharacterized protein. (801 aa)
	mus81	ERCC4 domain-containing protein. (613 aa)
	faap24	Uncharacterized protein. (216 aa)
	Usp1-b	Ubiquitin carboxyl-terminal hydrolase. (780 aa)
	Rad26	Uncharacterized protein. (798 aa)
	fancd2	Uncharacterized protein. (1445 aa)
	fan1	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1015 aa)
	fanci	Uncharacterized protein. (1337 aa)
	ube2t	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (192 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FG45	A0A1L8FQI3	A0A1L8FG45	A0A1L8FQI3	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.423
A0A1L8FG45	A0A1L8FV65	A0A1L8FG45	A0A1L8FV65	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.423
A0A1L8FG45	A0A1L8GE59	A0A1L8FG45	A0A1L8GE59	Uncharacterized protein.	NTF2 domain-containing protein.	0.790
A0A1L8FG45	A0A1L8HCW5	A0A1L8FG45	A0A1L8HCW5	Uncharacterized protein.	Uncharacterized protein.	0.897
A0A1L8FG45	Dclre1a.L	A0A1L8FG45	A0A1L8FI53	Uncharacterized protein.	DRMBL domain-containing protein.	0.506
A0A1L8FG45	Fanca.L	A0A1L8FG45	A0A310UBA7	Uncharacterized protein.	Fanconi_A_N domain-containing protein.	0.897
A0A1L8FG45	Fancl.L	A0A1L8FG45	A0A1L8G7F1	Uncharacterized protein.	RING-type domain-containing protein.	0.897
A0A1L8FG45	Fancm.L	A0A1L8FG45	A0A1L8F9Q1	Uncharacterized protein.	Uncharacterized protein.	0.935
A0A1L8FG45	Usp1-b	A0A1L8FG45	A0A1L8GLJ6	Uncharacterized protein.	Ubiquitin carboxyl-terminal hydrolase.	0.411
A0A1L8FG45	dclre1b	A0A1L8FG45	A0A1L8HEY3	Uncharacterized protein.	Lactamase_B domain-containing protein.	0.432
A0A1L8FG45	ercc1	A0A1L8FG45	A0A1L8FKK3	Uncharacterized protein.	Uncharacterized protein.	0.828
A0A1L8FG45	faap24	A0A1L8FG45	A0A1L8GLD2	Uncharacterized protein.	Uncharacterized protein.	0.887
A0A1L8FG45	fan1	A0A1L8FG45	A0A1L8H092	Uncharacterized protein.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.693
A0A1L8FG45	fancc	A0A1L8FG45	A0A1L8HYI1	Uncharacterized protein.	Uncharacterized protein.	0.887
A0A1L8FG45	fancd2	A0A1L8FG45	A0A1L8GP71	Uncharacterized protein.	Uncharacterized protein.	0.707
A0A1L8FG45	fancf	A0A1L8FG45	A0A1L8F8Q2	Uncharacterized protein.	Uncharacterized protein.	0.897
A0A1L8FG45	fancg	A0A1L8FG45	A0A1L8HS68	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.897
A0A1L8FG45	fanci	A0A1L8FG45	A0A1L8H0X8	Uncharacterized protein.	Uncharacterized protein.	0.736
A0A1L8FG45	mus81	A0A1L8FG45	A0A1L8GJY4	Uncharacterized protein.	ERCC4 domain-containing protein.	0.661
A0A1L8FG45	nutf2	A0A1L8FG45	Q7SZ24	Uncharacterized protein.	Nutf2-prov protein.	0.790