31 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8I2K6	SET domain-containing protein. (297 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	uba52	MGC80109 protein. (128 aa)
	rps27a	MGC81889 protein. (156 aa)
	prmt5	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (633 aa)
	ttc5-2	LOC431931 protein. (431 aa)
	jmy	WH2 domain-containing protein. (842 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	Kxd1.L	KxDL domain-containing protein. (195 aa)
	Jmy.S	Uncharacterized protein. (818 aa)
	ubc	Uncharacterized protein. (533 aa)
	ttc5	TTC5_OB domain-containing protein. (442 aa)
	Prmt5.S	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (633 aa)
	kxd1	KxDL domain-containing protein. (195 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	A0A1L8H7N8	SAM domain-containing protein. (681 aa)
	Mdm4.S	RanBP2-type domain-containing protein. (423 aa)
	A0A1L8H4Q1	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (200 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	mdm2	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
	A0A1L8GUE8	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (488 aa)
	ep300-2	Uncharacterized protein. (2492 aa)
	ep300	Uncharacterized protein. (2495 aa)
	Smyd2.S	SET domain-containing protein. (369 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	Smyd2-b	Uncharacterized protein. (430 aa)
	A0A1L8FTA7	Ubiquitin-like domain-containing protein. (105 aa)
	ehmt2	Uncharacterized protein. (1101 aa)
	ehmt1	Uncharacterized protein. (1278 aa)
	Ehmt1.S	Uncharacterized protein. (1284 aa)
	A0A1L8EMN5	SAM domain-containing protein. (754 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EMN5	A0A1L8H4Q1	A0A1L8EMN5	A0A1L8H4Q1	SAM domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.740
A0A1L8EMN5	Tp53.L	A0A1L8EMN5	A0A1L8H4M6	SAM domain-containing protein.	P53 domain-containing protein.	0.740
A0A1L8FTA7	A0A1L8G5V1	A0A1L8FTA7	A0A1L8G5V1	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.989
A0A1L8FTA7	A0A1L8GUE8	A0A1L8FTA7	A0A1L8GUE8	Ubiquitin-like domain-containing protein.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.800
A0A1L8FTA7	A0A1L8H4Q1	A0A1L8FTA7	A0A1L8H4Q1	Ubiquitin-like domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.414
A0A1L8FTA7	A0A1L8HCZ9	A0A1L8FTA7	A0A1L8HCZ9	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.908
A0A1L8FTA7	Ehmt1.S	A0A1L8FTA7	A0A1L8F125	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.599
A0A1L8FTA7	Mdm4.S	A0A1L8FTA7	A0A1L8H6P1	Ubiquitin-like domain-containing protein.	RanBP2-type domain-containing protein.	0.817
A0A1L8FTA7	Smyd2-b	A0A1L8FTA7	A0A1L8G170	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.413
A0A1L8FTA7	Smyd2.S	A0A1L8FTA7	A0A1L8G691	Ubiquitin-like domain-containing protein.	SET domain-containing protein.	0.413
A0A1L8FTA7	Tp53.L	A0A1L8FTA7	A0A1L8H4M6	Ubiquitin-like domain-containing protein.	P53 domain-containing protein.	0.414
A0A1L8FTA7	ehmt1	A0A1L8FTA7	A0A1L8F5Y0	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.599
A0A1L8FTA7	ehmt2	A0A1L8FTA7	A0A1L8F8K0	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.599
A0A1L8FTA7	ep300	A0A1L8FTA7	A0A1L8GGW2	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.404
A0A1L8FTA7	ep300-2	A0A1L8FTA7	A0A1L8GNI9	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.404
A0A1L8FTA7	mdm2	A0A1L8FTA7	A0A1L8GYI7	Ubiquitin-like domain-containing protein.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.800
A0A1L8FTA7	rps27a	A0A1L8FTA7	Q6GMC1	Ubiquitin-like domain-containing protein.	MGC81889 protein.	0.989
A0A1L8FTA7	ttc5	A0A1L8FTA7	A0A1L8HPT6	Ubiquitin-like domain-containing protein.	TTC5_OB domain-containing protein.	0.487
A0A1L8FTA7	ttc5-2	A0A1L8FTA7	A0JMT7	Ubiquitin-like domain-containing protein.	LOC431931 protein.	0.487
A0A1L8FTA7	ubc	A0A1L8FTA7	A0A1L8HQK4	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.907