STRINGSTRING
hist1h4a hist1h4a H2B-2 H2B-2 anapc1 anapc1 fam89a fam89a orc3 orc3 prim2 prim2 Psmd2.S Psmd2.S A0A1L8G3T0 A0A1L8G3T0 A0A1L8G5V1 A0A1L8G5V1 psme4 psme4 A0A1L8G614 A0A1L8G614 A0A1L8G6R5 A0A1L8G6R5 A0A1L8G6S1 A0A1L8G6S1 A0A1L8G6Z0 A0A1L8G6Z0 A0A1L8G784 A0A1L8G784 A0A1L8G795 A0A1L8G795 fam89a-2 fam89a-2 mcm9 mcm9 Psmd2.L Psmd2.L A0A1L8GBH4 A0A1L8GBH4 zmcm3 zmcm3 Psmd13.S Psmd13.S fen1 fen1 Psma1.S Psma1.S psmd7 psmd7 Cdt1.S Cdt1.S Ccne1.S Ccne1.S mcm5 mcm5 rbx1 rbx1 mcm2 mcm2 A0A1L8GI18 A0A1L8GI18 fen1-2 fen1-2 Anapc5.L Anapc5.L pola2 pola2 mcm3 mcm3 mcm6.2 mcm6.2 Xcdc6 Xcdc6 A0A1L8EKT2 A0A1L8EKT2 Psmd3.S Psmd3.S psmd11 psmd11 psmc5 psmc5 cdc27 cdc27 psma7 psma7 A0A1L8ENC4 A0A1L8ENC4 Psmd12.S Psmd12.S A0A1L8ENU1 A0A1L8ENU1 Orc2.S Orc2.S psmd3 psmd3 A0A1L8ERZ6 A0A1L8ERZ6 Cdc6.L Cdc6.L psmd11-2 psmd11-2 cdc27-2 cdc27-2 psma7-2 psma7-2 Anapc11.L Anapc11.L ube2c ube2c Psmd12.L Psmd12.L atad5 atad5 Mcm6.2.L Mcm6.2.L orc4 orc4 A0A1L8EVW9 A0A1L8EVW9 A0A1L8EWW0 A0A1L8EWW0 Meiob.L Meiob.L A0A1L8EZQ1 A0A1L8EZQ1 pcna pcna H2B H2B psmb8 psmb8 psma3 psma3 psmd9-2 psmd9-2 prim1 prim1 psmb1 psmb1 psmd6 psmd6 rcbtb2 rcbtb2 psmd14 psmd14 psmc3 psmc3 rfc5 rfc5 psma4 psma4 gins4 gins4 gins1 gins1 psmb7.2 psmb7.2 ubc-2 ubc-2 rfc4 rfc4 Q70PC5_XENLA Q70PC5_XENLA pole3 pole3 psme3-2 psme3-2 uba52 uba52 psmc5-2 psmc5-2 psmb2 psmb2 psma5 psma5 rps27a rps27a psme2 psme2 psmd9 psmd9 cdc16 cdc16 anapc7-2 anapc7-2 psma6 psma6 rpa3-2 rpa3-2 psmb7-2 psmb7-2 psmd7-2 psmd7-2 anapc7 anapc7 psme1 psme1 psme3 psme3 psmf1 psmf1 rpa3 rpa3 psmd10 psmd10 psmb3 psmb3 Psmb3 Psmb3 ube2c-2 ube2c-2 anapc10-2 anapc10-2 anapc10 anapc10 psma1 psma1 MGC114992 MGC114992 rfc3 rfc3 ccna2 ccna2 psmb6 psmb6 gmnn gmnn psmc3-a psmc3-a psmc2-2 psmc2-2 Hist1h4d.L Hist1h4d.L A0A310U368 A0A310U368 A0A310TNW1 A0A310TNW1 A0A310TML1 A0A310TML1 A0A310TMH3 A0A310TMH3 A0A310TM08 A0A310TM08 Skp2.L Skp2.L A0A1L8I2J2 A0A1L8I2J2 A0A1L8EZW5 A0A1L8EZW5 Psmc6.S Psmc6.S psmc1 psmc1 A0A1L8F0R3 A0A1L8F0R3 A0A1L8F0S4 A0A1L8F0S4 Psmd10.S Psmd10.S A0A1L8F3K4 A0A1L8F3K4 Psmb9.S Psmb9.S Psmd8.S Psmd8.S psmb4 psmb4 A0A1L8F5A2 A0A1L8F5A2 anapc2 anapc2 cdc26 cdc26 psmd5 psmd5 psmb7 psmb7 Psmd8.L Psmd8.L Psmc1.L Psmc1.L Pole2.L Pole2.L psmc6 psmc6 Psmb4.L Psmb4.L A0A1L8FDD6 A0A1L8FDD6 anapc16 anapc16 Dna2.S Dna2.S ube2s ube2s A0A1L8FHS4 A0A1L8FHS4 A0A1L8FHT5 A0A1L8FHT5 A0A1L8FHT9 A0A1L8FHT9 anapc16-2 anapc16-2 lig1 lig1 ube2s-2 ube2s-2 gins2 gins2 ccne1 ccne1 Orc6.L Orc6.L A0A1L8GLZ6 A0A1L8GLZ6 Orc1.L Orc1.L A0A1L8GMX9 A0A1L8GMX9 A0A1L8GN61 A0A1L8GN61 mcm5-2 mcm5-2 Rbx1.L Rbx1.L Mcm2.L Mcm2.L A0A1L8GQD1 A0A1L8GQD1 skp1 skp1 A0A1L8GRZ1 A0A1L8GRZ1 A0A1L8GS29 A0A1L8GS29 psmc2 psmc2 cdc23 cdc23 skp1-2 skp1-2 Pole4.L Pole4.L Cdc23.L Cdc23.L mcm10 mcm10 H2afv.S H2afv.S pold2 pold2 MCM7 MCM7 A0A1L8H4R2 A0A1L8H4R2 A0A1L8H5K7 A0A1L8H5K7 Pola1.S Pola1.S Psmb2.S Psmb2.S Kpna6.S Kpna6.S Cdk2.S Cdk2.S Rcbtb1.S Rcbtb1.S Ccna1.S Ccna1.S A0A1L8HB55 A0A1L8HB55 A0A1L8HBW3 A0A1L8HBW3 A0A1L8HCZ9 A0A1L8HCZ9 Rpa1.L Rpa1.L Rfc2.L Rfc2.L Cdk2.L Cdk2.L Rcbtb1.L Rcbtb1.L Ccna1.L Ccna1.L A0A1L8HK04 A0A1L8HK04 Ccna2.S Ccna2.S h2afz h2afz kxd1 kxd1 Psme1.S Psme1.S A0A1L8HPK4 A0A1L8HPK4 psmb5 psmb5 Cdc45.S Cdc45.S ubc ubc Rfc5.S Rfc5.S anapc4 anapc4 rfc1 rfc1 Fzr1.L Fzr1.L A0A1L8HVW6 A0A1L8HVW6 Kxd1.L Kxd1.L A0A1L8HX68 A0A1L8HX68 psmb11 psmb11 psmb5-2 psmb5-2 pole pole cdc45 cdc45 A0A1L8FQA5 A0A1L8FQA5 Anapc15-a Anapc15-a A0A1L8FRQ0 A0A1L8FRQ0 psma2 psma2 mcm4 mcm4 A0A1L8FTA7 A0A1L8FTA7 Ccne2.S Ccne2.S anapc15 anapc15 Pold1.L Pold1.L A0A1L8FPM5 A0A1L8FPM5 A0A1L8FQ56 A0A1L8FQ56 dbf4 dbf4 mcm6 mcm6 Gmnn.L Gmnn.L Mcm4.S Mcm4.S Orc5.L Orc5.L Ccne2.L Ccne2.L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hist1h4aHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H2B-2Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (233 aa)
anapc1APC1_C domain-containing protein. (1948 aa)
fam89aUncharacterized protein. (166 aa)
orc3ORC_WH_C domain-containing protein. (709 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (513 aa)
Psmd2.S26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (899 aa)
A0A1L8G3T026S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (922 aa)
A0A1L8G5V1Ubiquitin-like domain-containing protein. (156 aa)
psme4Uncharacterized protein. (1828 aa)
A0A1L8G614MCM domain-containing protein; Belongs to the MCM family. (798 aa)
A0A1L8G6R5Histone H2B; Belongs to the histone H2B family. (347 aa)
A0A1L8G6S1Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (238 aa)
A0A1L8G6Z0Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A0A1L8G784Uncharacterized protein. (171 aa)
A0A1L8G795Histone H2B; Belongs to the histone H2B family. (126 aa)
fam89a-2Uncharacterized protein. (166 aa)
mcm9MCM domain-containing protein; Belongs to the MCM family. (1143 aa)
Psmd2.L26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (899 aa)
A0A1L8GBH4Uncharacterized protein. (148 aa)
zmcm3DNA helicase; Belongs to the MCM family. (806 aa)
Psmd13.SPCI domain-containing protein. (364 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (382 aa)
Psma1.SProteasome subunit alpha type. (295 aa)
psmd7MPN domain-containing protein. (320 aa)
Cdt1.SCDT1 domain-containing protein. (615 aa)
Ccne1.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
mcm5DNA helicase; Belongs to the MCM family. (735 aa)
rbx1RING-type domain-containing protein. (120 aa)
mcm2DNA helicase; Belongs to the MCM family. (885 aa)
A0A1L8GI18Uncharacterized protein. (364 aa)
fen1-2Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (382 aa)
Anapc5.LUncharacterized protein. (759 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (673 aa)
mcm3DNA helicase; Belongs to the MCM family. (807 aa)
mcm6.2DNA helicase; Belongs to the MCM family. (825 aa)
Xcdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (554 aa)
A0A1L8EKT2Importin N-terminal domain-containing protein. (1129 aa)
Psmd3.SPCI domain-containing protein. (498 aa)
psmd11PCI domain-containing protein. (422 aa)
psmc5AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
cdc27Uncharacterized protein. (833 aa)
psma7Proteasome subunit alpha type. (247 aa)
A0A1L8ENC4AAA domain-containing protein. (1731 aa)
Psmd12.SPCI domain-containing protein. (455 aa)
A0A1L8ENU1Uncharacterized protein; Belongs to the histone H2B family. (98 aa)
Orc2.SUncharacterized protein. (558 aa)
psmd3PCI domain-containing protein. (547 aa)
A0A1L8ERZ6Importin N-terminal domain-containing protein. (871 aa)
Cdc6.LCell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (645 aa)
psmd11-2PCI domain-containing protein. (422 aa)
cdc27-2Uncharacterized protein. (834 aa)
psma7-2Proteasome subunit alpha type. (248 aa)
Anapc11.LRING-type domain-containing protein. (143 aa)
ube2cUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
Psmd12.LPCI domain-containing protein. (455 aa)
atad5AAA domain-containing protein. (1740 aa)
Mcm6.2.LDNA helicase; Belongs to the MCM family. (823 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (432 aa)
A0A1L8EVW9Uncharacterized protein; Belongs to the histone H2B family. (98 aa)
A0A1L8EWW0Uncharacterized protein. (1359 aa)
Meiob.LUncharacterized protein. (470 aa)
A0A1L8EZQ1Proteasome subunit alpha type. (236 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
H2BHistone H2B; Belongs to the histone H2B family. (126 aa)
psmb8Proteasome subunit beta. (271 aa)
psma3Proteasome subunit alpha type. (255 aa)
psmd9-2MGC53232 protein. (213 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa)
psmb1Proteasome subunit beta. (239 aa)
psmd6P44s10-prov protein. (389 aa)
rcbtb2Chc1l-prov protein. (526 aa)
psmd14Psmd14-prov protein. (310 aa)
psmc3Psmc3-b protein; Belongs to the AAA ATPase family. (423 aa)
rfc5Rfc5-prov protein. (335 aa)
psma4Proteasome subunit alpha type. (261 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (221 aa)
gins1MGC80254 protein. (196 aa)
psmb7.2Proteasome subunit beta. (279 aa)
ubc-2Ubc-prov protein. (609 aa)
rfc4Replication factor C p37 subunit. (363 aa)
Q70PC5_XENLAImportin subunit alpha; Belongs to the importin alpha family. (537 aa)
pole3DNA polymerase epsilon p17 subunit. (147 aa)
psme3-2Psme3 protein. (254 aa)
uba52MGC80109 protein. (128 aa)
psmc5-2MGC80185 protein; Belongs to the AAA ATPase family. (415 aa)
psmb2Proteasome subunit beta. (199 aa)
psma5Proteasome subunit alpha type. (247 aa)
rps27aMGC81889 protein. (156 aa)
psme2MGC84168 protein. (242 aa)
psmd9MGC84770 protein. (208 aa)
cdc16Cdc16-prov protein. (621 aa)
anapc7-2Anapc7-prov protein. (565 aa)
psma6Proteasome subunit alpha type. (246 aa)
rpa3-2Rpa3-prov protein. (121 aa)
psmb7-2Proteasome subunit beta. (277 aa)
psmd7-2MGC84052 protein. (320 aa)
anapc7MGC81861 protein. (565 aa)
psme1LOC494646 protein. (244 aa)
psme3Psme3b protein. (254 aa)
psmf1LOC495127 protein. (263 aa)
rpa3LOC495401 protein. (121 aa)
psmd10LOC495968 protein. (227 aa)
psmb3Proteasome subunit beta. (205 aa)
Psmb3Proteasome subunit beta. (205 aa)
ube2c-2LOC496302 protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
anapc10-2Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
psma1Proteasome subunit alpha type. (261 aa)
MGC114992MGC114992 protein; Belongs to the cullin family. (776 aa)
rfc3MGC115007 protein. (356 aa)
ccna2MGC130969 protein; Belongs to the cyclin family. (415 aa)
psmb6Proteasome subunit beta. (233 aa)
gmnnGMNN protein. (219 aa)
psmc3-a26S proteasome regulatory subunit 6A-A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). (423 aa)
psmc2-2XMSS1 protein; Belongs to the AAA ATPase family. (433 aa)
Hist1h4d.LHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A0A310U368Histone H2B; Belongs to the histone H2B family. (94 aa)
A0A310TNW1Prot_ATP_ID_OB domain-containing protein. (153 aa)
A0A310TML1CENP-T_C domain-containing protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (43 aa)
A0A310TMH3DUF4203 domain-containing protein. (227 aa)
A0A310TM08Histone H2B; Belongs to the histone H2B family. (126 aa)
Skp2.LF-box domain-containing protein. (420 aa)
A0A1L8I2J2Uncharacterized protein. (170 aa)
A0A1L8EZW5Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (352 aa)
Psmc6.SAAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
psmc1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
A0A1L8F0R3Uncharacterized protein. (136 aa)
A0A1L8F0S4Uncharacterized protein. (84 aa)
Psmd10.SANK_REP_REGION domain-containing protein. (270 aa)
A0A1L8F3K4Proteasome subunit beta. (279 aa)
Psmb9.SProteasome subunit beta. (215 aa)
Psmd8.SPCI domain-containing protein. (271 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (249 aa)
A0A1L8F5A2VWFA domain-containing protein. (635 aa)
anapc2CULLIN_2 domain-containing protein; Belongs to the cullin family. (810 aa)
cdc26Uncharacterized protein. (84 aa)
psmd5Uncharacterized protein. (505 aa)
psmb7Proteasome subunit beta. (277 aa)
Psmd8.LPCI domain-containing protein. (271 aa)
Psmc1.LAAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
Pole2.LDNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (569 aa)
psmc6AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
Psmb4.LProteasome subunit beta; Belongs to the peptidase T1B family. (249 aa)
A0A1L8FDD6VWFA domain-containing protein. (377 aa)
anapc16Uncharacterized protein. (144 aa)
Dna2.SUncharacterized protein. (1053 aa)
ube2sUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (211 aa)
A0A1L8FHS4Prot_ATP_ID_OB domain-containing protein. (59 aa)
A0A1L8FHT5AAA domain-containing protein. (240 aa)
A0A1L8FHT9Uncharacterized protein. (94 aa)
anapc16-2Uncharacterized protein. (144 aa)
lig1DNA ligase. (1062 aa)
ube2s-2UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (211 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
ccne1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
Orc6.LUncharacterized protein. (252 aa)
A0A1L8GLZ6Proteasome subunit alpha type. (261 aa)
Orc1.LOrigin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (886 aa)
A0A1L8GMX9Protein kinase domain-containing protein. (509 aa)
A0A1L8GN61Uncharacterized protein. (244 aa)
mcm5-2DNA helicase; Belongs to the MCM family. (735 aa)
Rbx1.LRING-type domain-containing protein. (168 aa)
Mcm2.LDNA helicase; Belongs to the MCM family. (886 aa)
A0A1L8GQD1DUF4203 domain-containing protein. (566 aa)
skp1Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
A0A1L8GRZ1Histone H2A; Belongs to the histone H2A family. (221 aa)
A0A1L8GS29Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (268 aa)
psmc2AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
cdc23TPR_REGION domain-containing protein. (581 aa)
skp1-2Uncharacterized protein; Belongs to the SKP1 family. (221 aa)
Pole4.LCBFD_NFYB_HMF domain-containing protein. (206 aa)
Cdc23.LTPR_REGION domain-containing protein. (580 aa)
mcm10Mcm10 domain-containing protein. (860 aa)
H2afv.SHistone H2A; Belongs to the histone H2A family. (234 aa)
pold2Uncharacterized protein. (463 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (720 aa)
A0A1L8H4R2Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (584 aa)
A0A1L8H5K7Importin subunit alpha; Belongs to the importin alpha family. (538 aa)
Pola1.SDNA polymerase. (718 aa)
Psmb2.SProteasome subunit beta. (199 aa)
Kpna6.SImportin subunit alpha; Belongs to the importin alpha family. (534 aa)
Cdk2.SProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
Rcbtb1.SBTB domain-containing protein. (600 aa)
Ccna1.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (418 aa)
A0A1L8HB55BZIP domain-containing protein. (304 aa)
A0A1L8HBW3Importin subunit alpha; Belongs to the importin alpha family. (539 aa)
A0A1L8HCZ9Uncharacterized protein. (307 aa)
Rpa1.LReplication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (609 aa)
Rfc2.LAAA domain-containing protein. (359 aa)
Cdk2.LProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
Rcbtb1.LBTB domain-containing protein. (600 aa)
Ccna1.LCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (421 aa)
A0A1L8HK04Uncharacterized protein. (779 aa)
Ccna2.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (415 aa)
h2afzHistone H2A; Belongs to the histone H2A family. (128 aa)
kxd1KxDL domain-containing protein. (195 aa)
Psme1.SUncharacterized protein. (244 aa)
A0A1L8HPK4Uncharacterized protein. (256 aa)
psmb5Proteasome subunit beta. (257 aa)
Cdc45.SUncharacterized protein. (580 aa)
ubcUncharacterized protein. (533 aa)
Rfc5.SAAA domain-containing protein. (335 aa)
anapc4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (789 aa)
rfc1Replication factor C subunit 1. (1147 aa)
Fzr1.LWD_REPEATS_REGION domain-containing protein. (251 aa)
A0A1L8HVW6WD_REPEATS_REGION domain-containing protein. (218 aa)
Kxd1.LKxDL domain-containing protein. (195 aa)
A0A1L8HX68Ubiquitin-like domain-containing protein. (173 aa)
psmb11Proteasome subunit beta. (276 aa)
psmb5-2Proteasome subunit beta. (257 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2285 aa)
cdc45Uncharacterized protein. (567 aa)
A0A1L8FQA5Histone H2B; Belongs to the histone H2B family. (126 aa)
Anapc15-aUncharacterized protein. (120 aa)
A0A1L8FRQ0CULLIN_2 domain-containing protein; Belongs to the cullin family. (701 aa)
psma2Proteasome subunit alpha type. (234 aa)
mcm4DNA helicase; Belongs to the MCM family. (858 aa)
A0A1L8FTA7Ubiquitin-like domain-containing protein. (105 aa)
Ccne2.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (430 aa)
anapc15Uncharacterized protein. (120 aa)
Pold1.LDNA polymerase. (1109 aa)
A0A1L8FPM5Uncharacterized protein. (363 aa)
A0A1L8FQ56Histone H2B; Belongs to the histone H2B family. (126 aa)
dbf4Uncharacterized protein. (661 aa)
mcm6DNA helicase; Belongs to the MCM family. (821 aa)
Gmnn.LUncharacterized protein. (213 aa)
Mcm4.SDNA helicase; Belongs to the MCM family. (863 aa)
Orc5.LAAA_16 domain-containing protein. (440 aa)
Ccne2.LCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (397 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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