STRINGSTRING
fgf23.1-2 fgf23.1-2 fgf1-2 fgf1-2 fgfr4 fgfr4 LOC100495408.L LOC100495408.L fgfr1-2 fgfr1-2 A0A1L8H8Y4 A0A1L8H8Y4 A0A1L8HAQ5 A0A1L8HAQ5 gab2 gab2 frs2 frs2 pik3c3 pik3c3 Gab1.L Gab1.L fgf10-2 fgf10-2 fgf2-2 fgf2-2 fgf9-A fgf9-A ins-2 ins-2 fgf7-2 fgf7-2 gab1 gab1 ptpn11b ptpn11b fgf8 fgf8 Ptpn11.S Ptpn11.S fgf20 fgf20 A0A1L8HH63 A0A1L8HH63 A0A1L8HJ12 A0A1L8HJ12 A0A1L8HJ43 A0A1L8HJ43 gab2-2 gab2-2 A0A1L8HKQ7 A0A1L8HKQ7 A0A1L8HLD0 A0A1L8HLD0 fgf2 fgf2 fgf5 fgf5 A0A1L8HS44 A0A1L8HS44 Fgfr3.L Fgfr3.L fgf5-2 fgf5-2 A0A1L8HH35 A0A1L8HH35 fgf22 fgf22 A0A1L8I158 A0A1L8I158 fgf10 fgf10 fgf6-2 fgf6-2 fgf1 fgf1 Fgfr4.S Fgfr4.S Frs2.S Frs2.S fgf7 fgf7 fgfr1 fgfr1 fgf23.1 fgf23.1 Fgf23.2.S Fgf23.2.S fgf6 fgf6 tlr9 tlr9 Fgf4.L Fgf4.L fgf19-2 fgf19-2 A0A1L8GIQ8 A0A1L8GIQ8 fgf4 fgf4 fgf3 fgf3 fgf19 fgf19 ins ins pik3cb-2 pik3cb-2 A0A1L8GA65 A0A1L8GA65 sos1-2 sos1-2 pik3cb pik3cb A0A1L8G3Z7 A0A1L8G3Z7 sos1 sos1 pik3r4-2 pik3r4-2 pik3r4 pik3r4 A0A1L8FNH3 A0A1L8FNH3 A0A1L8FND1 A0A1L8FND1 fgfr2-2 fgfr2-2 A0A1L8FH73 A0A1L8FH73 A0A1L8FG16 A0A1L8FG16 A0A1L8FEK1 A0A1L8FEK1 fgfr2 fgfr2 fgf13-2 fgf13-2 FGF16 FGF16 fgf13 fgf13 A0A1L8F2F1 A0A1L8F2F1 Pdpk1.L Pdpk1.L grb2-2 grb2-2 pdpk1 pdpk1 grb2 grb2 Fgf23.2.L Fgf23.2.L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf23.1-2Uncharacterized protein; Belongs to the heparin-binding growth factors family. (244 aa)
fgf1-2Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
fgfr4Fibroblast growth factor receptor. (807 aa)
LOC100495408.LNucleoplasmin domain-containing protein. (134 aa)
fgfr1-2Fibroblast growth factor receptor. (812 aa)
A0A1L8H8Y4Uncharacterized protein. (92 aa)
A0A1L8HAQ5Uncharacterized protein. (779 aa)
gab2PH domain-containing protein. (673 aa)
frs2IRS-type PTB domain-containing protein. (518 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
Gab1.LPH domain-containing protein. (682 aa)
fgf10-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
fgf2-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
fgf9-AFibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
ins-2Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
fgf7-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
gab1MGC81548 protein. (691 aa)
ptpn11bTyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
Ptpn11.STyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
fgf20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
A0A1L8HH63Uncharacterized protein; Belongs to the heparin-binding growth factors family. (111 aa)
A0A1L8HJ12Uncharacterized protein. (781 aa)
A0A1L8HJ43Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
gab2-2PH domain-containing protein. (677 aa)
A0A1L8HKQ7Uncharacterized protein. (925 aa)
A0A1L8HLD0Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
A0A1L8HS44Phosphatidylinositol 3-kinase catalytic subunit type 3. (847 aa)
Fgfr3.LFibroblast growth factor receptor. (821 aa)
fgf5-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
A0A1L8HH35Uncharacterized protein. (92 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (175 aa)
A0A1L8I158Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
fgf6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (156 aa)
Fgfr4.SFibroblast growth factor receptor. (825 aa)
Frs2.SIRS-type PTB domain-containing protein. (509 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
fgfr1Fibroblast growth factor receptor. (810 aa)
fgf23.1Uncharacterized protein; Belongs to the heparin-binding growth factors family. (244 aa)
Fgf23.2.SUncharacterized protein; Belongs to the heparin-binding growth factors family. (256 aa)
fgf6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
tlr9TIR domain-containing protein; Belongs to the Toll-like receptor family. (830 aa)
Fgf4.LFibroblast growth factor; Belongs to the heparin-binding growth factors family. (235 aa)
fgf19-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa)
A0A1L8GIQ8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (301 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
pik3cb-2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
A0A1L8GA65Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1009 aa)
sos1-2Uncharacterized protein. (1325 aa)
pik3cbUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
A0A1L8G3Z7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
sos1Uncharacterized protein. (1325 aa)
pik3r4-2Uncharacterized protein. (1363 aa)
pik3r4Uncharacterized protein. (1363 aa)
A0A1L8FNH3Uncharacterized protein. (249 aa)
A0A1L8FND1IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
fgfr2-2Fibroblast growth factor receptor. (832 aa)
A0A1L8FH73Uncharacterized protein. (243 aa)
A0A1L8FG16Uncharacterized protein. (559 aa)
A0A1L8FEK1Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (199 aa)
fgfr2Fibroblast growth factor receptor. (830 aa)
fgf13-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
fgf13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
A0A1L8F2F1Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (202 aa)
Pdpk1.LProtein kinase domain-containing protein. (528 aa)
grb2-2Uncharacterized protein. (229 aa)
pdpk1Protein kinase domain-containing protein. (507 aa)
grb2Uncharacterized protein. (229 aa)
Fgf23.2.LUncharacterized protein; Belongs to the heparin-binding growth factors family. (256 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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