87 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8HVF6	Uncharacterized protein. (889 aa)
	grb7	Uncharacterized protein. (532 aa)
	Dok5.L	IRS-type PTB domain-containing protein. (379 aa)
	grb2	Uncharacterized protein. (229 aa)
	A0A1L8EP71	Uncharacterized protein. (430 aa)
	grb7-2	Uncharacterized protein. (532 aa)
	A0A1L8ESU4	IRS-type PTB domain-containing protein. (403 aa)
	grb2-2	Uncharacterized protein. (229 aa)
	grb14	Uncharacterized protein. (451 aa)
	A0A1L8F3B0	Uncharacterized protein. (1205 aa)
	shc1	Uncharacterized protein. (605 aa)
	fndc3c	Uncharacterized protein. (1205 aa)
	Shc1.L	Uncharacterized protein. (601 aa)
	A0A1L8FDS8	Uncharacterized protein. (255 aa)
	A0A1L8FG16	Uncharacterized protein. (559 aa)
	A0A1L8FI75	GDNF domain-containing protein. (309 aa)
	A0A1L8FI88	Uncharacterized protein. (371 aa)
	Ret.L	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1096 aa)
	nxpe2	Uncharacterized protein. (579 aa)
	A0A1L8FL88	Uncharacterized protein. (427 aa)
	A0A1L8FL92	Uncharacterized protein. (530 aa)
	Nxpe4.S	Uncharacterized protein. (506 aa)
	A0A1L8FLA0	Uncharacterized protein. (444 aa)
	A0A1L8FLA1	Endo/exonuclease/phosphatase domain-containing protein. (724 aa)
	A0A1L8FLA7	Uncharacterized protein. (511 aa)
	A0A1L8FLB6	Uncharacterized protein. (545 aa)
	A0A1L8FLC1	Uncharacterized protein. (505 aa)
	A0A1L8FLD6	Uncharacterized protein. (552 aa)
	A0A1L8FLE7	Uncharacterized protein. (533 aa)
	grb10	Uncharacterized protein. (535 aa)
	A0A1L8FSJ9	IRS-type PTB domain-containing protein. (431 aa)
	grb10-2	Uncharacterized protein. (591 aa)
	Dok6.L	IRS-type PTB domain-containing protein. (414 aa)
	sos1	Uncharacterized protein. (1325 aa)
	A0A1L8G3Z7	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
	fndc3b	Uncharacterized protein. (1205 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	sos1-2	Uncharacterized protein. (1325 aa)
	A0A1L8GA65	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1009 aa)
	fndc3b-2	Uncharacterized protein. (1204 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	dok4	IRS-type PTB domain-containing protein. (320 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
	Artn.S	TGF_BETA_2 domain-containing protein. (232 aa)
	Dok4.L	IRS-type PTB domain-containing protein. (320 aa)
	Prkacb.S	Uncharacterized protein; Belongs to the protein kinase superfamily. (338 aa)
	artn	TGF_BETA_2 domain-containing protein. (333 aa)
	Dok2.S	Uncharacterized protein. (428 aa)
	Gfra2.S	GDNF family receptor alpha; Belongs to the GDNFR family. (458 aa)
	A0A1L8GTK6	Uncharacterized protein. (1885 aa)
	Frs2.S	IRS-type PTB domain-containing protein. (509 aa)
	gfra3	Uncharacterized protein. (417 aa)
	Pdlim7.L	Uncharacterized protein. (421 aa)
	pdlim7	Uncharacterized protein. (421 aa)
	gfra3-2	Uncharacterized protein. (413 aa)
	frs2	IRS-type PTB domain-containing protein. (518 aa)
	A0A1L8GZQ2	Uncharacterized protein. (1444 aa)
	Gfra2.L	GDNF family receptor alpha; Belongs to the GDNFR family. (458 aa)
	dok2	Uncharacterized protein. (414 aa)
	A0A1L8H2K5	Uncharacterized protein; Belongs to the protein kinase superfamily. (383 aa)
	Pspn.L	TGF_BETA_2 domain-containing protein. (172 aa)
	fndc3a	Uncharacterized protein. (1202 aa)
	gab2	PH domain-containing protein. (673 aa)
	fndc3a-2	Uncharacterized protein. (1200 aa)
	gab2-2	PH domain-containing protein. (677 aa)
	A0A1L8HK23	IRS-type PTB domain-containing protein. (526 aa)
	gfra4	Uncharacterized protein. (460 aa)
	A0A1L8HMA6	Uncharacterized protein. (583 aa)
	A0A1L8HND0	TGF_BETA_2 domain-containing protein. (221 aa)
	A0A1L8HNI8	Uncharacterized protein. (721 aa)
	A0A1L8HPF0	Uncharacterized protein. (629 aa)
	Gdnf.S	Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (227 aa)
	Gfra4.L	Uncharacterized protein. (344 aa)
	A0A1L8HWT4	Uncharacterized protein. (717 aa)
	A0A1L8HWX7	TGF_BETA_2 domain-containing protein. (211 aa)
	A0A1L8HZ53	Uncharacterized protein. (628 aa)
	A0A1L8I158	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
	Gdnf.L	TGF_BETA_2 domain-containing protein. (332 aa)
	Gab1.L	PH domain-containing protein. (682 aa)
	PIK3R1	Phosphoinositide-3-kinase. (722 aa)
	pik3r3	MGC84470 protein. (461 aa)
	gab1	MGC81548 protein. (691 aa)
	pik3r2	Pik3r2-prov protein. (457 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	pik3r1	MGC80357 protein. (722 aa)
	prkaca	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EP71	A0A1L8G3Z7	A0A1L8EP71	A0A1L8G3Z7	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.526
A0A1L8EP71	A0A1L8GA65	A0A1L8EP71	A0A1L8GA65	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.526
A0A1L8EP71	A0A1L8HND0	A0A1L8EP71	A0A1L8HND0	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.423
A0A1L8EP71	A0A1L8HNI8	A0A1L8EP71	A0A1L8HNI8	Uncharacterized protein.	Uncharacterized protein.	0.474
A0A1L8EP71	A0A1L8HWT4	A0A1L8EP71	A0A1L8HWT4	Uncharacterized protein.	Uncharacterized protein.	0.474
A0A1L8EP71	A0A1L8HWX7	A0A1L8EP71	A0A1L8HWX7	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.423
A0A1L8EP71	PIK3R1	A0A1L8EP71	B7ZRD8	Uncharacterized protein.	Phosphoinositide-3-kinase.	0.474
A0A1L8EP71	Ret.L	A0A1L8EP71	A0A1L8FK90	Uncharacterized protein.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.602
A0A1L8EP71	grb2	A0A1L8EP71	A0A1L8EMZ6	Uncharacterized protein.	Uncharacterized protein.	0.511
A0A1L8EP71	grb2-2	A0A1L8EP71	A0A1L8EUF2	Uncharacterized protein.	Uncharacterized protein.	0.511
A0A1L8EP71	pik3cb	A0A1L8EP71	A0A1L8G4U9	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.437
A0A1L8EP71	pik3cb-2	A0A1L8EP71	A0A1L8GB27	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.437
A0A1L8EP71	pik3r1	A0A1L8EP71	Q6GQ43	Uncharacterized protein.	MGC80357 protein.	0.474
A0A1L8EP71	pik3r2	A0A1L8EP71	Q6DD15	Uncharacterized protein.	Pik3r2-prov protein.	0.474
A0A1L8EP71	pik3r3	A0A1L8EP71	Q66IU1	Uncharacterized protein.	MGC84470 protein.	0.474
A0A1L8ESU4	Ret.L	A0A1L8ESU4	A0A1L8FK90	IRS-type PTB domain-containing protein.	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.	0.594
A0A1L8ESU4	grb2	A0A1L8ESU4	A0A1L8EMZ6	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.402
A0A1L8ESU4	grb2-2	A0A1L8ESU4	A0A1L8EUF2	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.402
A0A1L8FDS8	A0A1L8HND0	A0A1L8FDS8	A0A1L8HND0	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.715
A0A1L8FDS8	A0A1L8HWX7	A0A1L8FDS8	A0A1L8HWX7	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.715