43 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hbegf	EGF-like domain-containing protein. (196 aa)
	rnf41-2	LOC495085 protein. (315 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	A0A1L8HW99	Uncharacterized protein. (576 aa)
	A0A1L8HW93	Uncharacterized protein. (349 aa)
	ereg-2	Uncharacterized protein. (156 aa)
	btc	EGF-like domain-containing protein. (170 aa)
	Egf.L	Uncharacterized protein. (1031 aa)
	ubc	Uncharacterized protein. (533 aa)
	A0A1L8HN17	EGF-like domain-containing protein. (514 aa)
	A0A1L8HN10	Uncharacterized protein. (376 aa)
	Btc.S	EGF-like domain-containing protein. (287 aa)
	ereg	Uncharacterized protein. (156 aa)
	erbb3-2	Protein kinase domain-containing protein. (1347 aa)
	A0A1L8HD37	Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (219 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	cul5	CULLIN_2 domain-containing protein; Belongs to the cullin family. (780 aa)
	rnf41	RING-type domain-containing protein. (317 aa)
	erbb3	Protein kinase domain-containing protein. (1331 aa)
	cryba1.2	Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (209 aa)
	usp8-2	Uncharacterized protein; Belongs to the peptidase C19 family. (1063 aa)
	nrg4	EGF-like domain-containing protein. (99 aa)
	rps27a	MGC81889 protein. (156 aa)
	usp8	Uncharacterized protein; Belongs to the peptidase C19 family. (1060 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	egfr-2	Receptor protein-tyrosine kinase. (1210 aa)
	A0A1L8FTA7	Ubiquitin-like domain-containing protein. (105 aa)
	egfr	Receptor protein-tyrosine kinase. (1208 aa)
	A0A1L8FKB1	Uncharacterized protein. (237 aa)
	A0A1L8FK96	Uncharacterized protein. (358 aa)
	A0A1L8FA58	Non-specific serine/threonine protein kinase. (516 aa)
	akt2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa)
	MGC78893	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (485 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	Ptpn18.S	Uncharacterized protein. (511 aa)
	stub1-2	Uncharacterized protein. (309 aa)
	A0A1L8EWP4	Receptor protein-tyrosine kinase. (1083 aa)
	erbb2	Receptor protein-tyrosine kinase. (1299 aa)
	stub1	Uncharacterized protein. (310 aa)
	A0A1L8EPK3	Receptor protein-tyrosine kinase. (1256 aa)
	A0A1L8EKP1	Receptor protein-tyrosine kinase. (1290 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	uba52	MGC80109 protein. (128 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EKP1	A0A1L8EPK3	A0A1L8EKP1	A0A1L8EPK3	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.803
A0A1L8EKP1	A0A1L8G5V1	A0A1L8EKP1	A0A1L8G5V1	Receptor protein-tyrosine kinase.	Ubiquitin-like domain-containing protein.	0.443
A0A1L8EKP1	A0A1L8HCZ9	A0A1L8EKP1	A0A1L8HCZ9	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.490
A0A1L8EKP1	A0A1L8HN10	A0A1L8EKP1	A0A1L8HN10	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.706
A0A1L8EKP1	A0A1L8HN17	A0A1L8EKP1	A0A1L8HN17	Receptor protein-tyrosine kinase.	EGF-like domain-containing protein.	0.706
A0A1L8EKP1	A0A1L8HW93	A0A1L8EKP1	A0A1L8HW93	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.706
A0A1L8EKP1	A0A1L8HW99	A0A1L8EKP1	A0A1L8HW99	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.706
A0A1L8EKP1	Btc.S	A0A1L8EKP1	A0A1L8HMG1	Receptor protein-tyrosine kinase.	EGF-like domain-containing protein.	0.446
A0A1L8EKP1	Egf.L	A0A1L8EKP1	A0A1L8HUT3	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.937
A0A1L8EKP1	Ptpn18.S	A0A1L8EKP1	A0A1L8EZM1	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.464
A0A1L8EKP1	btc	A0A1L8EKP1	A0A1L8HVB1	Receptor protein-tyrosine kinase.	EGF-like domain-containing protein.	0.446
A0A1L8EKP1	cul5	A0A1L8EKP1	A0A1L8HAU2	Receptor protein-tyrosine kinase.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.476
A0A1L8EKP1	erbb2	A0A1L8EKP1	A0A1L8ES20	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.900
A0A1L8EKP1	ereg	A0A1L8EKP1	A0A1L8HMF2	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.838
A0A1L8EKP1	ereg-2	A0A1L8EKP1	A0A1L8HVM0	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.838
A0A1L8EKP1	hbegf	A0A1L8EKP1	A0A1L8GVF5	Receptor protein-tyrosine kinase.	EGF-like domain-containing protein.	0.728
A0A1L8EKP1	rnf41	A0A1L8EKP1	A0A1L8H9R0	Receptor protein-tyrosine kinase.	RING-type domain-containing protein.	0.648
A0A1L8EKP1	rnf41-2	A0A1L8EKP1	Q5XH23	Receptor protein-tyrosine kinase.	LOC495085 protein.	0.648
A0A1L8EKP1	rps27a	A0A1L8EKP1	Q6GMC1	Receptor protein-tyrosine kinase.	MGC81889 protein.	0.443
A0A1L8EKP1	stub1	A0A1L8EKP1	A0A1L8ER33	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.580