12 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8I158	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (608 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	Gab1.L	PH domain-containing protein. (682 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	gab1	MGC81548 protein. (691 aa)
	grb2-2	Uncharacterized protein. (229 aa)
	A0A1L8FG16	Uncharacterized protein. (559 aa)
	hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
	Met.S	Uncharacterized protein. (1354 aa)
	Met.L	Uncharacterized protein. (1355 aa)
	hgf-2	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (710 aa)
	grb2	Uncharacterized protein. (229 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FG16	Gab1.L	A0A1L8FG16	A0A310TNH6	Uncharacterized protein.	PH domain-containing protein.	0.886
A0A1L8FG16	Met.L	A0A1L8FG16	A0A1L8GYT6	Uncharacterized protein.	Uncharacterized protein.	0.681
A0A1L8FG16	Met.S	A0A1L8FG16	A0A1L8GU34	Uncharacterized protein.	Uncharacterized protein.	0.681
A0A1L8FG16	gab1	A0A1L8FG16	Q6AZI1	Uncharacterized protein.	MGC81548 protein.	0.886
A0A1L8FG16	grb2	A0A1L8FG16	A0A1L8EMZ6	Uncharacterized protein.	Uncharacterized protein.	0.917
A0A1L8FG16	grb2-2	A0A1L8FG16	A0A1L8EUF2	Uncharacterized protein.	Uncharacterized protein.	0.917
A0A1L8FG16	hgf	A0A1L8FG16	A0A1L8GTY1	Uncharacterized protein.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.415
A0A1L8FG16	hgf-2	A0A1L8FG16	A0A1L8GZD1	Uncharacterized protein.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.415
A0A1L8I158	Gab1.L	A0A1L8I158	A0A310TNH6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	PH domain-containing protein.	0.886
A0A1L8I158	Met.L	A0A1L8I158	A0A1L8GYT6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.681
A0A1L8I158	Met.S	A0A1L8I158	A0A1L8GU34	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.681
A0A1L8I158	gab1	A0A1L8I158	Q6AZI1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	MGC81548 protein.	0.886
A0A1L8I158	grb2	A0A1L8I158	A0A1L8EMZ6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.917
A0A1L8I158	grb2-2	A0A1L8I158	A0A1L8EUF2	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Uncharacterized protein.	0.917
A0A1L8I158	hgf	A0A1L8I158	A0A1L8GTY1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.415
A0A1L8I158	hgf-2	A0A1L8I158	A0A1L8GZD1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.415
Gab1.L	A0A1L8FG16	A0A310TNH6	A0A1L8FG16	PH domain-containing protein.	Uncharacterized protein.	0.886
Gab1.L	A0A1L8I158	A0A310TNH6	A0A1L8I158	PH domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.886
Gab1.L	Met.L	A0A310TNH6	A0A1L8GYT6	PH domain-containing protein.	Uncharacterized protein.	0.907
Gab1.L	Met.S	A0A310TNH6	A0A1L8GU34	PH domain-containing protein.	Uncharacterized protein.	0.907