158 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8EKF7	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (802 aa)
	Psmd3.S	PCI domain-containing protein. (498 aa)
	psmd11	PCI domain-containing protein. (422 aa)
	psmc5	AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
	smurf2	E3 ubiquitin-protein ligase. (751 aa)
	Psmd12.S	PCI domain-containing protein. (455 aa)
	A0A1L8EPZ7	E3 ubiquitin-protein ligase. (729 aa)
	crebbp	Uncharacterized protein. (2424 aa)
	A0A1L8ERN2	Uncharacterized protein. (635 aa)
	psmd3	PCI domain-containing protein. (547 aa)
	psmd11-2	PCI domain-containing protein. (422 aa)
	Psmd12.L	PCI domain-containing protein. (455 aa)
	A0A1L8EV30	E3 ubiquitin-protein ligase. (751 aa)
	Smurf1.L	E3 ubiquitin-protein ligase. (731 aa)
	crebbp-2	Uncharacterized protein. (2453 aa)
	A0A1L8EZQ1	Proteasome subunit alpha type. (236 aa)
	A0A1L8EZW5	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (352 aa)
	Psmc6.S	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
	psmc1	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	Notch1.S	Uncharacterized protein. (2524 aa)
	Psmd10.S	ANK_REP_REGION domain-containing protein. (270 aa)
	mamld1	Uncharacterized protein. (994 aa)
	A0A1L8F3B0	Uncharacterized protein. (1205 aa)
	A0A1L8F3K4	Proteasome subunit beta. (279 aa)
	Psmb9.S	Proteasome subunit beta. (215 aa)
	A0A1L8F3L0	Uncharacterized protein. (2377 aa)
	Psmd8.S	PCI domain-containing protein. (271 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	psmb4	Proteasome subunit beta; Belongs to the peptidase T1B family. (249 aa)
	A0A1L8F5A2	VWFA domain-containing protein. (635 aa)
	notch1	Uncharacterized protein. (2521 aa)
	psmd5	Uncharacterized protein. (505 aa)
	psmb7	Proteasome subunit beta. (277 aa)
	Mamld1.L	Uncharacterized protein. (998 aa)
	fndc3c	Uncharacterized protein. (1205 aa)
	Psmd8.L	PCI domain-containing protein. (271 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	A0A1L8F9E3	SKIP_SNW domain-containing protein. (460 aa)
	Psmc1.L	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	psmc6	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
	A0A1L8FDB0	Mothers against decapentaplegic homolog. (514 aa)
	Psmb4.L	Proteasome subunit beta; Belongs to the peptidase T1B family. (249 aa)
	A0A1L8FDD6	VWFA domain-containing protein. (377 aa)
	A0A1L8FDR5	HMG box domain-containing protein. (482 aa)
	A0A1L8FG47	Uncharacterized protein. (110 aa)
	A0A1L8FHS4	Prot_ATP_ID_OB domain-containing protein. (59 aa)
	A0A1L8FHT5	AAA domain-containing protein. (240 aa)
	A0A1L8FHT9	Uncharacterized protein. (94 aa)
	Tcf7l2.L	HMG box domain-containing protein. (482 aa)
	hes4	Uncharacterized protein. (277 aa)
	A0A1L8FND8	TEA domain-containing protein. (433 aa)
	A0A1L8FRF1	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (816 aa)
	psma2	Proteasome subunit alpha type. (234 aa)
	A0A1L8FTA7	Ubiquitin-like domain-containing protein. (105 aa)
	Zfhx4.L	Uncharacterized protein. (3521 aa)
	A0A1L8FW79	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (781 aa)
	A0A1L8FZ88	Uncharacterized protein. (2352 aa)
	A0A1L8FZ92	Uncharacterized protein. (1074 aa)
	Psmd2.S	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (899 aa)
	A0A1L8G3T0	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (922 aa)
	hes1	Uncharacterized protein. (267 aa)
	fndc3b	Uncharacterized protein. (1205 aa)
	hes6.2	Uncharacterized protein. (187 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	hes1-2	Uncharacterized protein. (267 aa)
	Psmd2.L	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (899 aa)
	fndc3b-2	Uncharacterized protein. (1204 aa)
	hes6.2-2	Uncharacterized protein. (183 aa)
	Psmd13.S	PCI domain-containing protein. (364 aa)
	A0A1L8GDE6	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (286 aa)
	tead1	TEA domain-containing protein. (447 aa)
	Psma1.S	Proteasome subunit alpha type. (295 aa)
	cbfb	Uncharacterized protein. (185 aa)
	psmd7	MPN domain-containing protein. (320 aa)
	zfhx3	Uncharacterized protein. (3615 aa)
	ep300	Uncharacterized protein. (2495 aa)
	A0A1L8GI18	Uncharacterized protein. (364 aa)
	A0A1L8GIH7	TEA domain-containing protein. (496 aa)
	cbfb-2	Uncharacterized protein. (185 aa)
	zfhx3-2	Uncharacterized protein. (3617 aa)
	A0A1L8GLZ6	Proteasome subunit alpha type. (261 aa)
	A0A1L8GN61	Uncharacterized protein. (244 aa)
	ep300-2	Uncharacterized protein. (2492 aa)
	A0A1L8GQX1	Uncharacterized protein. (101 aa)
	A0A1L8GR26	HMG box domain-containing protein. (487 aa)
	A0A1L8GR86	MamL-1 domain-containing protein. (971 aa)
	tcf7l1	HMG box domain-containing protein. (551 aa)
	psmc2	AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
	A0A1L8GUE8	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (488 aa)
	mdm2	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	A0A1L8H4Q1	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (200 aa)
	Psmb2.S	Proteasome subunit beta. (199 aa)
	fndc3a	Uncharacterized protein. (1202 aa)
	maml2	MamL-1 domain-containing protein. (994 aa)
	A0A1L8HB55	BZIP domain-containing protein. (304 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	fndc3a-2	Uncharacterized protein. (1200 aa)
	maml2-2	MamL-1 domain-containing protein. (995 aa)
	Rbpj.S	Uncharacterized protein. (485 aa)
	A0A1L8HLU1	MamL-1 domain-containing protein. (1090 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	Psme1.S	Uncharacterized protein. (244 aa)
	A0A1L8HPK4	Uncharacterized protein. (256 aa)
	A0A1L8HPL6	Uncharacterized protein. (2452 aa)
	psmb5	Proteasome subunit beta. (257 aa)
	ubc	Uncharacterized protein. (533 aa)
	A0A1L8HRY9	Mothers against decapentaplegic homolog. (549 aa)
	rbpj	Uncharacterized protein. (487 aa)
	A0A1L8HUI0	MamL-1 domain-containing protein. (219 aa)
	A0A1L8HUJ3	Uncharacterized protein. (420 aa)
	A0A1L8HUL3	Uncharacterized protein. (668 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	psmb5-2	Proteasome subunit beta. (257 aa)
	A0A1L8HZ26	Uncharacterized protein. (2449 aa)
	A0A1L8I2V3	Mothers against decapentaplegic homolog. (510 aa)
	Hes4.L	Orange domain-containing protein. (171 aa)
	A0A310TNW1	Prot_ATP_ID_OB domain-containing protein. (153 aa)
	psmc2-2	XMSS1 protein; Belongs to the AAA ATPase family. (433 aa)
	tcf7l1-2	Transcription factor XTCF-3b. (554 aa)
	XMam1	XMam1 protein. (1039 aa)
	psmc3-a	26S proteasome regulatory subunit 6A-A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). (423 aa)
	snw1	MGC132028 protein. (535 aa)
	psmb6	Proteasome subunit beta. (233 aa)
	ccn2	Ctgf protein. (343 aa)
	psma1	Proteasome subunit alpha type. (261 aa)
	Psmb3	Proteasome subunit beta. (205 aa)
	psmb3	Proteasome subunit beta. (205 aa)
	psmd10	LOC495968 protein. (227 aa)
	psmf1	LOC495127 protein. (263 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	psme3	Psme3b protein. (254 aa)
	psme1	LOC494646 protein. (244 aa)
	tead4	MGC81567 protein. (433 aa)
	psmd7-2	MGC84052 protein. (320 aa)
	psmb7-2	Proteasome subunit beta. (277 aa)
	psma6	Proteasome subunit alpha type. (246 aa)
	psmd9	MGC84770 protein. (208 aa)
	psme2	MGC84168 protein. (242 aa)
	rps27a	MGC81889 protein. (156 aa)
	psma5	Proteasome subunit alpha type. (247 aa)
	psmb2	Proteasome subunit beta. (199 aa)
	psmc5-2	MGC80185 protein; Belongs to the AAA ATPase family. (415 aa)
	uba52	MGC80109 protein. (128 aa)
	psme3-2	Psme3 protein. (254 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	psmb7.2	Proteasome subunit beta. (279 aa)
	psma4	Proteasome subunit alpha type. (261 aa)
	psmc3	Psmc3-b protein; Belongs to the AAA ATPase family. (423 aa)
	ctnnb1-2	Ctnnb1-prov protein. (781 aa)
	psmd14	Psmd14-prov protein. (310 aa)
	psmd6	P44s10-prov protein. (389 aa)
	psmb1	Proteasome subunit beta. (239 aa)
	psmd9-2	MGC53232 protein. (213 aa)
	psma3	Proteasome subunit alpha type. (255 aa)
	ccnd1	Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	psmb8	Proteasome subunit beta. (271 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EKF7	A0A1L8ERN2	A0A1L8EKF7	A0A1L8ERN2	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Uncharacterized protein.	0.900
A0A1L8EKF7	A0A1L8F3L0	A0A1L8EKF7	A0A1L8F3L0	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Uncharacterized protein.	0.446
A0A1L8EKF7	A0A1L8F9E3	A0A1L8EKF7	A0A1L8F9E3	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	SKIP_SNW domain-containing protein.	0.625
A0A1L8EKF7	A0A1L8FRF1	A0A1L8EKF7	A0A1L8FRF1	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.901
A0A1L8EKF7	A0A1L8FTA7	A0A1L8EKF7	A0A1L8FTA7	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Ubiquitin-like domain-containing protein.	0.561
A0A1L8EKF7	A0A1L8FW79	A0A1L8EKF7	A0A1L8FW79	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.901
A0A1L8EKF7	A0A1L8G5V1	A0A1L8EKF7	A0A1L8G5V1	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Ubiquitin-like domain-containing protein.	0.625
A0A1L8EKF7	A0A1L8GR86	A0A1L8EKF7	A0A1L8GR86	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	MamL-1 domain-containing protein.	0.517
A0A1L8EKF7	A0A1L8H4Q1	A0A1L8EKF7	A0A1L8H4Q1	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.586
A0A1L8EKF7	A0A1L8HCZ9	A0A1L8EKF7	A0A1L8HCZ9	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Uncharacterized protein.	0.536
A0A1L8EKF7	A0A1L8HLU1	A0A1L8EKF7	A0A1L8HLU1	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	MamL-1 domain-containing protein.	0.834
A0A1L8EKF7	A0A1L8HUL3	A0A1L8EKF7	A0A1L8HUL3	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Uncharacterized protein.	0.834
A0A1L8EKF7	A0A1L8HX68	A0A1L8EKF7	A0A1L8HX68	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Ubiquitin-like domain-containing protein.	0.561
A0A1L8EKF7	Notch1.S	A0A1L8EKF7	A0A1L8F124	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Uncharacterized protein.	0.446
A0A1L8EKF7	Rbpj.S	A0A1L8EKF7	A0A1L8HL49	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Uncharacterized protein.	0.871
A0A1L8EKF7	Tp53.L	A0A1L8EKF7	A0A1L8H4M6	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	P53 domain-containing protein.	0.586
A0A1L8EKF7	XMam1	A0A1L8EKF7	B7ZQH4	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	XMam1 protein.	0.899
A0A1L8EKF7	crebbp	A0A1L8EKF7	A0A1L8EQR2	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Uncharacterized protein.	0.975
A0A1L8EKF7	crebbp-2	A0A1L8EKF7	A0A1L8EYE5	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Uncharacterized protein.	0.975
A0A1L8EKF7	ep300	A0A1L8EKF7	A0A1L8GGW2	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Uncharacterized protein.	0.981