77 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L8F093	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1684 aa)
	Jup.S	Uncharacterized protein. (791 aa)
	A0A1L8EK95	Uncharacterized protein. (95 aa)
	rab7a-2	MGC68523 protein. (207 aa)
	jup	LOC398496 protein. (737 aa)
	cdc42ep4	MGC81381 protein. (300 aa)
	cav1a	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	git2	MGC80878 protein. (759 aa)
	rab7a	Rab7-prov protein. (207 aa)
	vamp1	LOC495063 protein. (101 aa)
	itsn1	Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for cdc42, and thereby stimulates actin nucleation mediated by wasl and the arp2/3 complex (By similarity). Involved in endocytosis of activated egfr, and probably also other growth factor receptors (By similarity). (1705 aa)
	cdc42ep1-2	LOC100137624 protein. (324 aa)
	A0A310TLQ6	Protein kinase domain-containing protein. (82 aa)
	depdc1b	Rho-GAP domain-containing protein. (529 aa)
	A0A1L8HQ07	Uncharacterized protein. (694 aa)
	A0A1L8HEX5	Uncharacterized protein. (522 aa)
	Git1	Uncharacterized protein. (737 aa)
	Arl13b.L	Uncharacterized protein. (472 aa)
	Itsn1.L	Uncharacterized protein. (1270 aa)
	lamtor1	Uncharacterized protein. (162 aa)
	Itsn1.S	Uncharacterized protein. (1670 aa)
	A0A1L8H562	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (223 aa)
	A0A1L8H4T5	Uncharacterized protein. (729 aa)
	A0A1L8GZ41	Uncharacterized protein. (574 aa)
	arhgap26-2	Uncharacterized protein. (759 aa)
	arhgap26	Uncharacterized protein. (759 aa)
	A0A1L8GU06	Uncharacterized protein. (574 aa)
	A0A1L8GQ14	Uncharacterized protein. (541 aa)
	cav3.1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (155 aa)
	cdc42ep1	CRIB domain-containing protein. (323 aa)
	wwp2-2	E3 ubiquitin-protein ligase. (732 aa)
	gfod2	GFO_IDH_MocA domain-containing protein. (384 aa)
	MGC53732	Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (202 aa)
	Arhgap1.L	Uncharacterized protein. (435 aa)
	A0A1L8GHW8	Uncharacterized protein. (401 aa)
	wwp2	E3 ubiquitin-protein ligase. (739 aa)
	Arhgap1.S	Uncharacterized protein. (473 aa)
	A0A1L8GCV0	CRIB domain-containing protein. (213 aa)
	A0A1L8GBH3	Non-specific serine/threonine protein kinase. (518 aa)
	gopc-2	PDZ domain-containing protein. (440 aa)
	gja1-2	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (379 aa)
	fmn2	FH2 domain-containing protein. (1611 aa)
	Cdc42ep3.L	CRIB domain-containing protein. (256 aa)
	Pak2.S	Non-specific serine/threonine protein kinase. (517 aa)
	gopc	PDZ domain-containing protein. (442 aa)
	gja1	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (379 aa)
	cdc42ep3	CRIB domain-containing protein. (256 aa)
	A0A1L8FY22	GFO_IDH_MocA domain-containing protein. (390 aa)
	A0A1L8FX70	ANK_REP_REGION domain-containing protein. (375 aa)
	A0A1L8FX67	Uncharacterized protein. (242 aa)
	A0A1L8FWB0	Anion exchange protein. (1225 aa)
	Arhgap21.L	Uncharacterized protein. (1786 aa)
	A0A1L8FVG0	Uncharacterized protein. (524 aa)
	A0A1L8FVE3	L27 domain-containing protein. (56 aa)
	slc4a7	Anion exchange protein. (1129 aa)
	Arhgap21.S	Uncharacterized protein. (1925 aa)
	A0A1L8FQQ4	Uncharacterized protein. (531 aa)
	Arhgap33.L	Uncharacterized protein. (1149 aa)
	Arhgap32.L	Uncharacterized protein. (1940 aa)
	Arhgap33.S	Uncharacterized protein. (1105 aa)
	A0A1L8FGH7	V-SNARE coiled-coil homology domain-containing protein. (191 aa)
	A0A1L8FGA0	Uncharacterized protein. (191 aa)
	arhgap32	Uncharacterized protein. (1989 aa)
	arhgap5-2	Uncharacterized protein. (1495 aa)
	A0A1L8FAW9	Uncharacterized protein. (1447 aa)
	fmn1	FH2 domain-containing protein. (1393 aa)
	cdc42bpb	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1731 aa)
	arhgap35-2	Uncharacterized protein. (1480 aa)
	A0A1L8F784	Uncharacterized protein. (1352 aa)
	A0A1L8F6T4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
	A0A1L8F475	Uncharacterized protein. (1350 aa)
	arhgap5	Uncharacterized protein. (1498 aa)
	arhgap35	Uncharacterized protein. (1476 aa)
	A0A1L8F2L6	Uncharacterized protein. (213 aa)
	A0A1L8F2K3	Uncharacterized protein. (438 aa)
	A0A1L8F1B3	Uncharacterized protein. (639 aa)
	steap3	Uncharacterized protein. (509 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EK95	A0A1L8FGA0	A0A1L8EK95	A0A1L8FGA0	Uncharacterized protein.	Uncharacterized protein.	0.551
A0A1L8EK95	A0A1L8FGH7	A0A1L8EK95	A0A1L8FGH7	Uncharacterized protein.	V-SNARE coiled-coil homology domain-containing protein.	0.432
A0A1L8EK95	A0A1L8FQQ4	A0A1L8EK95	A0A1L8FQQ4	Uncharacterized protein.	Uncharacterized protein.	0.425
A0A1L8EK95	A0A1L8FVE3	A0A1L8EK95	A0A1L8FVE3	Uncharacterized protein.	L27 domain-containing protein.	0.425
A0A1L8EK95	A0A1L8FVG0	A0A1L8EK95	A0A1L8FVG0	Uncharacterized protein.	Uncharacterized protein.	0.425
A0A1L8EK95	A0A1L8GBH3	A0A1L8EK95	A0A1L8GBH3	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.436
A0A1L8EK95	Pak2.S	A0A1L8EK95	A0A1L8G4S9	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.436
A0A1L8EK95	lamtor1	A0A1L8EK95	A0A1L8HBN4	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A1L8EK95	rab7a	A0A1L8EK95	Q6DCV5	Uncharacterized protein.	Rab7-prov protein.	0.498
A0A1L8EK95	rab7a-2	A0A1L8EK95	Q6PA99	Uncharacterized protein.	MGC68523 protein.	0.498
A0A1L8EK95	vamp1	A0A1L8EK95	Q5XH53	Uncharacterized protein.	LOC495063 protein.	0.432
A0A1L8F093	A0A1L8F1B3	A0A1L8F093	A0A1L8F1B3	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Uncharacterized protein.	0.413
A0A1L8F093	A0A1L8FGA0	A0A1L8F093	A0A1L8FGA0	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	Uncharacterized protein.	0.571
A0A1L8F093	cdc42ep4	A0A1L8F093	Q6NRU4	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	MGC81381 protein.	0.540
A0A1L8F1B3	A0A1L8F093	A0A1L8F1B3	A0A1L8F093	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.413
A0A1L8F1B3	A0A1L8FGA0	A0A1L8F1B3	A0A1L8FGA0	Uncharacterized protein.	Uncharacterized protein.	0.859
A0A1L8F1B3	A0A1L8FQQ4	A0A1L8F1B3	A0A1L8FQQ4	Uncharacterized protein.	Uncharacterized protein.	0.434
A0A1L8F1B3	A0A1L8FVE3	A0A1L8F1B3	A0A1L8FVE3	Uncharacterized protein.	L27 domain-containing protein.	0.434
A0A1L8F1B3	A0A1L8FVG0	A0A1L8F1B3	A0A1L8FVG0	Uncharacterized protein.	Uncharacterized protein.	0.434
A0A1L8F1B3	A0A1L8FY22	A0A1L8F1B3	A0A1L8FY22	Uncharacterized protein.	GFO_IDH_MocA domain-containing protein.	0.483