111 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Psmb9.S	Proteasome subunit beta. (215 aa)
	Psmd8.S	PCI domain-containing protein. (271 aa)
	psmb4	Proteasome subunit beta; Belongs to the peptidase T1B family. (249 aa)
	psmd9-2	MGC53232 protein. (213 aa)
	psmb1	Proteasome subunit beta. (239 aa)
	psmd6	P44s10-prov protein. (389 aa)
	psmd14	Psmd14-prov protein. (310 aa)
	psmc3	Psmc3-b protein; Belongs to the AAA ATPase family. (423 aa)
	psma4	Proteasome subunit alpha type. (261 aa)
	psmb7.2	Proteasome subunit beta. (279 aa)
	ubc-2	Ubc-prov protein. (609 aa)
	psme3-2	Psme3 protein. (254 aa)
	uba52	MGC80109 protein. (128 aa)
	psmc5-2	MGC80185 protein; Belongs to the AAA ATPase family. (415 aa)
	psmb2	Proteasome subunit beta. (199 aa)
	psma5	Proteasome subunit alpha type. (247 aa)
	rps27a	MGC81889 protein. (156 aa)
	psme2	MGC84168 protein. (242 aa)
	A0A1L8F5A2	VWFA domain-containing protein. (635 aa)
	psmd5	Uncharacterized protein. (505 aa)
	psmb7	Proteasome subunit beta. (277 aa)
	Psmd8.L	PCI domain-containing protein. (271 aa)
	Psmc1.L	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	psmc6	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
	Psmb4.L	Proteasome subunit beta; Belongs to the peptidase T1B family. (249 aa)
	A0A1L8FDD6	VWFA domain-containing protein. (377 aa)
	A0A1L8FEN9	Uncharacterized protein. (470 aa)
	gsk3a	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (424 aa)
	A0A1L8FHT5	AAA domain-containing protein. (240 aa)
	A0A1L8FHS4	Prot_ATP_ID_OB domain-containing protein. (59 aa)
	A0A1L8FHT9	Uncharacterized protein. (94 aa)
	btrc	Uncharacterized protein. (564 aa)
	A0A1L8FN20	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (422 aa)
	nfe2l3	BZIP domain-containing protein. (729 aa)
	A0A1L8FRQ0	CULLIN_2 domain-containing protein; Belongs to the cullin family. (701 aa)
	psma2	Proteasome subunit alpha type. (234 aa)
	A0A1L8FTA7	Ubiquitin-like domain-containing protein. (105 aa)
	nfe2l3-2	BZIP domain-containing protein. (715 aa)
	Psmd2.S	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (899 aa)
	A0A1L8G3T0	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (922 aa)
	A0A1L8G5V1	Ubiquitin-like domain-containing protein. (156 aa)
	Psmd2.L	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (899 aa)
	Psmd13.S	PCI domain-containing protein. (364 aa)
	Psma1.S	Proteasome subunit alpha type. (295 aa)
	psmd7	MPN domain-containing protein. (320 aa)
	rbx1	RING-type domain-containing protein. (120 aa)
	ep300	Uncharacterized protein. (2495 aa)
	Atf4.S	BZIP domain-containing protein. (342 aa)
	A0A1L8GI18	Uncharacterized protein. (364 aa)
	A0A1L8GLZ6	Proteasome subunit alpha type. (261 aa)
	A0A1L8GN61	Uncharacterized protein. (244 aa)
	Rbx1.L	RING-type domain-containing protein. (168 aa)
	ep300-2	Uncharacterized protein. (2492 aa)
	Atf4.L	BZIP domain-containing protein. (343 aa)
	skp1	Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
	psmc2	AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
	skp1-2	Uncharacterized protein; Belongs to the SKP1 family. (221 aa)
	A0A1L8H5Q6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	Psmb2.S	Proteasome subunit beta. (199 aa)
	A0A1L8HB55	BZIP domain-containing protein. (304 aa)
	A0A1L8HBT3	Uncharacterized protein. (28 aa)
	A0A1L8HBT4	Protein kinase domain-containing protein. (64 aa)
	A0A1L8HBY8	Protein kinase domain-containing protein. (298 aa)
	A0A1L8HCZ9	Uncharacterized protein. (307 aa)
	kxd1	KxDL domain-containing protein. (195 aa)
	Psme1.S	Uncharacterized protein. (244 aa)
	A0A1L8HPK4	Uncharacterized protein. (256 aa)
	psmb5	Proteasome subunit beta. (257 aa)
	ubc	Uncharacterized protein. (533 aa)
	Kxd1.L	KxDL domain-containing protein. (195 aa)
	A0A1L8HX68	Ubiquitin-like domain-containing protein. (173 aa)
	psmb5-2	Proteasome subunit beta. (257 aa)
	A0A310TNW1	Prot_ATP_ID_OB domain-containing protein. (153 aa)
	psmc2-2	XMSS1 protein; Belongs to the AAA ATPase family. (433 aa)
	psmc3-a	26S proteasome regulatory subunit 6A-A; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). (423 aa)
	psmb6	Proteasome subunit beta. (233 aa)
	MGC114992	MGC114992 protein; Belongs to the cullin family. (776 aa)
	psma1	Proteasome subunit alpha type. (261 aa)
	Psmb3	Proteasome subunit beta. (205 aa)
	psmb3	Proteasome subunit beta. (205 aa)
	psmd10	LOC495968 protein. (227 aa)
	psmf1	LOC495127 protein. (263 aa)
	psme3	Psme3b protein. (254 aa)
	nfe2l2	MGC53355 protein. (591 aa)
	nfe2l1	BZIP domain-containing protein. (718 aa)
	Psmd3.S	PCI domain-containing protein. (498 aa)
	psmd11	PCI domain-containing protein. (422 aa)
	psmc5	AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
	A0A1L8EM31	Sulfiredoxin. (114 aa)
	Psmd12.S	PCI domain-containing protein. (455 aa)
	psme1	LOC494646 protein. (244 aa)
	psmd7-2	MGC84052 protein. (320 aa)
	psmb7-2	Proteasome subunit beta. (277 aa)
	psma6	Proteasome subunit alpha type. (246 aa)
	Nfe2l2.S	BZIP domain-containing protein; Belongs to the bZIP family. (590 aa)
	crebbp	Uncharacterized protein. (2424 aa)
	psmd3	PCI domain-containing protein. (547 aa)
	A0A1L8ES08	BZIP domain-containing protein. (720 aa)
	psmd11-2	PCI domain-containing protein. (422 aa)
	psmd9	MGC84770 protein. (208 aa)
	psmb8	Proteasome subunit beta. (271 aa)
	psma3	Proteasome subunit alpha type. (255 aa)
	A0A1L8ETB1	Sulfiredoxin. (114 aa)
	Psmd12.L	PCI domain-containing protein. (455 aa)
	crebbp-2	Uncharacterized protein. (2453 aa)
	A0A1L8EZQ1	Proteasome subunit alpha type. (236 aa)
	A0A1L8EZW5	Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (352 aa)
	Psmc6.S	AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa)
	psmc1	AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
	Psmd10.S	ANK_REP_REGION domain-containing protein. (270 aa)
	A0A1L8F3K4	Proteasome subunit beta. (279 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EM31	Nfe2l2.S	A0A1L8EM31	A0A1L8EPD0	Sulfiredoxin.	BZIP domain-containing protein; Belongs to the bZIP family.	0.471
A0A1L8EM31	nfe2l2	A0A1L8EM31	Q640J4	Sulfiredoxin.	MGC53355 protein.	0.471
A0A1L8ES08	A0A1L8EZQ1	A0A1L8ES08	A0A1L8EZQ1	BZIP domain-containing protein.	Proteasome subunit alpha type.	0.482
A0A1L8ES08	A0A1L8EZW5	A0A1L8ES08	A0A1L8EZW5	BZIP domain-containing protein.	Proteasome endopeptidase complex; Belongs to the peptidase T1A family.	0.448
A0A1L8ES08	A0A1L8F3K4	A0A1L8ES08	A0A1L8F3K4	BZIP domain-containing protein.	Proteasome subunit beta.	0.441
A0A1L8ES08	A0A1L8F5A2	A0A1L8ES08	A0A1L8F5A2	BZIP domain-containing protein.	VWFA domain-containing protein.	0.493
A0A1L8ES08	A0A1L8FDD6	A0A1L8ES08	A0A1L8FDD6	BZIP domain-containing protein.	VWFA domain-containing protein.	0.493
A0A1L8ES08	A0A1L8FHS4	A0A1L8ES08	A0A1L8FHS4	BZIP domain-containing protein.	Prot_ATP_ID_OB domain-containing protein.	0.419
A0A1L8ES08	A0A1L8FHT5	A0A1L8ES08	A0A1L8FHT5	BZIP domain-containing protein.	AAA domain-containing protein.	0.441
A0A1L8ES08	A0A1L8FHT9	A0A1L8ES08	A0A1L8FHT9	BZIP domain-containing protein.	Uncharacterized protein.	0.419
A0A1L8ES08	A0A1L8FN20	A0A1L8ES08	A0A1L8FN20	BZIP domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.545
A0A1L8ES08	A0A1L8FRQ0	A0A1L8ES08	A0A1L8FRQ0	BZIP domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.585
A0A1L8ES08	A0A1L8G3T0	A0A1L8ES08	A0A1L8G3T0	BZIP domain-containing protein.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.576
A0A1L8ES08	A0A1L8G5V1	A0A1L8ES08	A0A1L8G5V1	BZIP domain-containing protein.	Ubiquitin-like domain-containing protein.	0.481
A0A1L8ES08	A0A1L8H5Q6	A0A1L8ES08	A0A1L8H5Q6	BZIP domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.545
A0A1L8ES08	A0A1L8HBT3	A0A1L8ES08	A0A1L8HBT3	BZIP domain-containing protein.	Uncharacterized protein.	0.545
A0A1L8ES08	A0A1L8HBT4	A0A1L8ES08	A0A1L8HBT4	BZIP domain-containing protein.	Protein kinase domain-containing protein.	0.545
A0A1L8ES08	A0A1L8HBY8	A0A1L8ES08	A0A1L8HBY8	BZIP domain-containing protein.	Protein kinase domain-containing protein.	0.545
A0A1L8ES08	A0A1L8HCZ9	A0A1L8ES08	A0A1L8HCZ9	BZIP domain-containing protein.	Uncharacterized protein.	0.451
A0A1L8ES08	A0A310TNW1	A0A1L8ES08	A0A310TNW1	BZIP domain-containing protein.	Prot_ATP_ID_OB domain-containing protein.	0.430