STRINGSTRING
pxdn pxdn A0A1L8EZT5 A0A1L8EZT5 A0A1L8FAF1 A0A1L8FAF1 Npm3.L Npm3.L H2B-2 H2B-2 pxdn-2 pxdn-2 Ccne1.S Ccne1.S prkacb prkacb Nasp.S Nasp.S ccne1 ccne1 Prkacb.S Prkacb.S Cdk2.S Cdk2.S Alb.S Alb.S ran ran LOC100189571 LOC100189571 npm3 npm3 actl6a actl6a fgf8 fgf8 prkaca prkaca H2B H2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pxdnUncharacterized protein. (1461 aa)
A0A1L8EZT5Tyrosine-protein kinase receptor. (1323 aa)
A0A1L8FAF1Tyrosine-protein kinase receptor. (1237 aa)
Npm3.LNucleoplasmin domain-containing protein. (240 aa)
H2B-2Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (233 aa)
pxdn-2Uncharacterized protein. (1464 aa)
Ccne1.SCyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
Nasp.STPR_REGION domain-containing protein. (590 aa)
ccne1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
Prkacb.SUncharacterized protein; Belongs to the protein kinase superfamily. (338 aa)
Cdk2.SProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
Alb.SUncharacterized protein. (607 aa)
ranGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (216 aa)
LOC100189571Uncharacterized protein. (608 aa)
npm3MGC85274 protein. (171 aa)
actl6aBaf53a-pending-prov protein; Belongs to the actin family. (429 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
prkacacAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
H2BHistone H2B; Belongs to the histone H2B family. (126 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.