32 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ctnnb1	Beta-catenin protein. (781 aa)
	dkk2-2	Dickkopf homolog 2. (255 aa)
	csnk1e	Casein kinase I epsilon; Belongs to the protein kinase superfamily. (416 aa)
	fzd2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	wnt10a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	fzd5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	wnt9b.2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	wnt4-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	gpc1	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (552 aa)
	gpc1-2	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (552 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	Wnt5b.S	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
	wnt16	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
	wif1	Uncharacterized protein. (374 aa)
	wnt16-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	A0A1L8HBL4	ANK_REP_REGION domain-containing protein. (263 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	wnt10b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
	Myo7a.L	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2177 aa)
	dkk2	Dickkopf_N domain-containing protein. (255 aa)
	Egf.L	Uncharacterized protein. (1031 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	Xwnt-8b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
	wnt10a-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8HBL4	ctnnb1	A0A1L8HBL4	Q63ZT4	ANK_REP_REGION domain-containing protein.	Beta-catenin protein.	0.548
Axin1.S	Egf.L	A0A1L8ER48	A0A1L8HUT3	Uncharacterized protein.	Uncharacterized protein.	0.479
Axin1.S	Lrp5.L	A0A1L8ER48	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.998
Axin1.S	Wnt1.L	A0A1L8ER48	A0A1L8HHR8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.931
Axin1.S	Wnt5b.S	A0A1L8ER48	A0A1L8GQS0	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.706
Axin1.S	Xwnt-8b	A0A1L8ER48	B7ZQM6	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.655
Axin1.S	csnk1e	A0A1L8ER48	Q9PUI2	Uncharacterized protein.	Casein kinase I epsilon; Belongs to the protein kinase superfamily.	0.995
Axin1.S	ctnnb1	A0A1L8ER48	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.999
Axin1.S	dkk1	A0A1L8ER48	A0A1L8FIS6	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.890
Axin1.S	dkk1-2	A0A1L8ER48	O57464	Uncharacterized protein.	Dickkopf homolog 1.	0.892
Axin1.S	dkk2	A0A1L8ER48	A0A1L8HM80	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.712
Axin1.S	dkk2-2	A0A1L8ER48	Q9DDA4	Uncharacterized protein.	Dickkopf homolog 2.	0.711
Axin1.S	fzd2	A0A1L8ER48	A0A1L8EL29	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.834
Axin1.S	fzd5	A0A1L8ER48	A0A1L8EPX2	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.689
Axin1.S	fzd7	A0A1L8ER48	A0A1L8EX17	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.778
Axin1.S	wif1	A0A1L8ER48	A0A1L8GYI2	Uncharacterized protein.	Uncharacterized protein.	0.758
Axin1.S	wif1-2	A0A1L8ER48	B7ZPZ2	Uncharacterized protein.	Wnt inhibitory factor-1.	0.758
Axin1.S	wnt1	A0A1L8ER48	A0A1L8H9S8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.931
Axin1.S	wnt10a	A0A1L8ER48	A0A1L8ENU7	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.531
Axin1.S	wnt10a-2	A0A1L8ER48	B7ZQU5	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.531