28 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	Kremen1.S	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (452 aa)
	Kit.L	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
	kremen1	Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
	A0A310U4X8	Glyceraldehyde-3-phosphate dehydrogenase. (294 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	Gapdh.S	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	dkk2-2	Dickkopf homolog 2. (255 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	Dkk3.S	Dickkopf_N domain-containing protein. (257 aa)
	A0A1L8FPY5	Uncharacterized protein. (443 aa)
	A0A1L8FPX8	Uncharacterized protein. (461 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	dkk2	Dickkopf_N domain-containing protein. (255 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	Kit.S	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
	dct	Uncharacterized protein. (520 aa)
	tyr	Uncharacterized protein. (532 aa)
	Pmel.S	PKD domain-containing protein. (720 aa)
	A0A1L8H5Q6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	Junb.L	BZIP domain-containing protein. (306 aa)
	wif1	Uncharacterized protein. (374 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FPX8	A0A1L8FPY5	A0A1L8FPX8	A0A1L8FPY5	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A1L8FPX8	Kit.L	A0A1L8FPX8	A0A1L8HTR4	Uncharacterized protein.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.499
A0A1L8FPX8	Kit.S	A0A1L8FPX8	A0A1L8HL85	Uncharacterized protein.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.499
A0A1L8FPX8	Pmel.S	A0A1L8FPX8	A0A1L8H9X6	Uncharacterized protein.	PKD domain-containing protein.	0.926
A0A1L8FPX8	dct	A0A1L8FPX8	A0A1L8HHA8	Uncharacterized protein.	Uncharacterized protein.	0.806
A0A1L8FPX8	tyr	A0A1L8FPX8	A0A1L8HAY8	Uncharacterized protein.	Uncharacterized protein.	0.905
A0A1L8FPY5	A0A1L8FPX8	A0A1L8FPY5	A0A1L8FPX8	Uncharacterized protein.	Uncharacterized protein.	0.901
A0A1L8FPY5	Kit.L	A0A1L8FPY5	A0A1L8HTR4	Uncharacterized protein.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.499
A0A1L8FPY5	Kit.S	A0A1L8FPY5	A0A1L8HL85	Uncharacterized protein.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.499
A0A1L8FPY5	Pmel.S	A0A1L8FPY5	A0A1L8H9X6	Uncharacterized protein.	PKD domain-containing protein.	0.926
A0A1L8FPY5	dct	A0A1L8FPY5	A0A1L8HHA8	Uncharacterized protein.	Uncharacterized protein.	0.802
A0A1L8FPY5	tyr	A0A1L8FPY5	A0A1L8HAY8	Uncharacterized protein.	Uncharacterized protein.	0.905
A0A1L8H5Q6	Axin1.S	A0A1L8H5Q6	A0A1L8ER48	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.999
A0A1L8H5Q6	Gapdh.S	A0A1L8H5Q6	Q7ZY52	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Glyceraldehyde-3-phosphate dehydrogenase.	0.404
A0A1L8H5Q6	Jun.L	A0A1L8H5Q6	A0A1L8GLZ4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	BZIP domain-containing protein; Belongs to the bZIP family.	0.598
A0A1L8H5Q6	Tp53.L	A0A1L8H5Q6	A0A1L8H4M6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	P53 domain-containing protein.	0.594
A0A1L8H5Q6	c-Jun	A0A1L8H5Q6	Q9PVZ1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	C-Jun protein; Belongs to the bZIP family.	0.600
A0A1L8H5Q6	ctnnb1	A0A1L8H5Q6	Q63ZT4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Beta-catenin protein.	0.999
A0A1L8H5Q6	dkk1	A0A1L8H5Q6	A0A1L8FIS6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Dickkopf_N domain-containing protein.	0.606
A0A1L8H5Q6	dkk1-2	A0A1L8H5Q6	O57464	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Dickkopf homolog 1.	0.606