6 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	Clspn.S	Claspin. (1286 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Clspn.S	Hus1	F8WKR8	Q8JHD8	Claspin.	Checkpoint protein; Belongs to the HUS1 family.	0.951
Clspn.S	chek1	F8WKR8	A0A1L8FFS1	Claspin.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.999
Clspn.S	chek1-2	F8WKR8	A0A1L8FL95	Claspin.	Protein kinase domain-containing protein.	0.999
Clspn.S	rad9a	F8WKR8	Q7ZZU5	Claspin.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.978
Clspn.S	topbp1	F8WKR8	A0A1L8FWJ6	Claspin.	Uncharacterized protein.	0.993
Hus1	Clspn.S	Q8JHD8	F8WKR8	Checkpoint protein; Belongs to the HUS1 family.	Claspin.	0.951
Hus1	chek1	Q8JHD8	A0A1L8FFS1	Checkpoint protein; Belongs to the HUS1 family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.981
Hus1	chek1-2	Q8JHD8	A0A1L8FL95	Checkpoint protein; Belongs to the HUS1 family.	Protein kinase domain-containing protein.	0.985
Hus1	rad9a	Q8JHD8	Q7ZZU5	Checkpoint protein; Belongs to the HUS1 family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.999
Hus1	topbp1	Q8JHD8	A0A1L8FWJ6	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.998
chek1	Clspn.S	A0A1L8FFS1	F8WKR8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Claspin.	0.999
chek1	Hus1	A0A1L8FFS1	Q8JHD8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Checkpoint protein; Belongs to the HUS1 family.	0.981
chek1	chek1-2	A0A1L8FFS1	A0A1L8FL95	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.900
chek1	rad9a	A0A1L8FFS1	Q7ZZU5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.983
chek1	topbp1	A0A1L8FFS1	A0A1L8FWJ6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.992
chek1-2	Clspn.S	A0A1L8FL95	F8WKR8	Protein kinase domain-containing protein.	Claspin.	0.999
chek1-2	Hus1	A0A1L8FL95	Q8JHD8	Protein kinase domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.985
chek1-2	chek1	A0A1L8FL95	A0A1L8FFS1	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.900
chek1-2	rad9a	A0A1L8FL95	Q7ZZU5	Protein kinase domain-containing protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.983
chek1-2	topbp1	A0A1L8FL95	A0A1L8FWJ6	Protein kinase domain-containing protein.	Uncharacterized protein.	0.992