44 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cdx2	MGC130987 protein. (256 aa)
	tbx3	Transcription factor Tbx3. (711 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)
	tbxt-2	MGC81453 protein. (432 aa)
	ing5	Inhibitor of growth protein. (236 aa)
	ap1m1	MGC114659 protein; Belongs to the adaptor complexes medium subunit family. (423 aa)
	cdx2-2	Homeobox domain-containing protein. (254 aa)
	vegt	Uncharacterized protein. (455 aa)
	Nipbl.L	Uncharacterized protein. (1074 aa)
	Vegt.L	Uncharacterized protein. (455 aa)
	smad6	Mothers against decapentaplegic homolog. (352 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	tbx3-A	Transcription repression factor Tbx3. (716 aa)
	smad6-2	Mothers against decapentaplegic homolog. (354 aa)
	ing2	Inhibitor of growth protein. (281 aa)
	fzd2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	Aurka.S	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (408 aa)
	cpsf4	Uncharacterized protein. (269 aa)
	A0A1L8ES96	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (554 aa)
	cpsf4-2	Uncharacterized protein. (269 aa)
	suv39h1	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (421 aa)
	Suv39h1.L	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (432 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	rad51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (336 aa)
	Sox17a.S	Uncharacterized protein. (377 aa)
	sox17b.1	Uncharacterized protein. (373 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	sox17b.1-2	Uncharacterized protein. (373 aa)
	tbxt	Uncharacterized protein. (432 aa)
	Chrd.1.S	Chordin; Belongs to the chordin family. (941 aa)
	A0A1L8GA23	Chordin; Belongs to the chordin family. (940 aa)
	A0A1L8GA54	Uncharacterized protein. (882 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	Wnt5b.S	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
	fgfr1	Fibroblast growth factor receptor. (810 aa)
	sfrp1	Uncharacterized protein. (311 aa)
	Fgfr4.S	Fibroblast growth factor receptor. (825 aa)
	fgfr4	Fibroblast growth factor receptor. (807 aa)
	Sfrp1.L	Uncharacterized protein. (311 aa)
	fgfr1-2	Fibroblast growth factor receptor. (812 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ES96	Sfrp1.L	A0A1L8ES96	A0A1L8H1S5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.678
A0A1L8ES96	Wnt5b.S	A0A1L8ES96	A0A1L8GQS0	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.910
A0A1L8ES96	sfrp1	A0A1L8ES96	A0A1L8GRT5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.679
A0A1L8ES96	wnt11	A0A1L8ES96	A0A1L8HJX1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.880
A0A1L8ES96	wnt11b	A0A1L8ES96	A0A1L8F6W4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.878
A0A1L8GA23	A0A1L8GA54	A0A1L8GA23	A0A1L8GA54	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.900
A0A1L8GA23	Chrd.1.S	A0A1L8GA23	A0A1L8G404	Chordin; Belongs to the chordin family.	Chordin; Belongs to the chordin family.	0.900
A0A1L8GA23	Sox17a.S	A0A1L8GA23	A0A1L8FT01	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.565
A0A1L8GA23	Vegt.L	A0A1L8GA23	A0A1L8I0H4	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.604
A0A1L8GA23	bmp4	A0A1L8GA23	B7ZPR8	Chordin; Belongs to the chordin family.	Bone morphogenetic protein 4.	0.994
A0A1L8GA23	bmp4-2	A0A1L8GA23	Q91703	Chordin; Belongs to the chordin family.	Bone morphogenetic protein 4.	0.994
A0A1L8GA23	fgfr1	A0A1L8GA23	A0A1L8GRK9	Chordin; Belongs to the chordin family.	Fibroblast growth factor receptor.	0.424
A0A1L8GA23	fgfr1-2	A0A1L8GA23	A0A1L8H273	Chordin; Belongs to the chordin family.	Fibroblast growth factor receptor.	0.424
A0A1L8GA23	smad6	A0A1L8GA23	A1L3N0	Chordin; Belongs to the chordin family.	Mothers against decapentaplegic homolog.	0.642
A0A1L8GA23	smad6-2	A0A1L8GA23	O57475	Chordin; Belongs to the chordin family.	Mothers against decapentaplegic homolog.	0.642
A0A1L8GA23	sox17b.1	A0A1L8GA23	A0A1L8FT40	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.546
A0A1L8GA23	sox17b.1-2	A0A1L8GA23	A0A1L8FZ03	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.489
A0A1L8GA23	tbxt	A0A1L8GA23	A0A1L8G2B1	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.925
A0A1L8GA23	tbxt-2	A0A1L8GA23	Q6INQ0	Chordin; Belongs to the chordin family.	MGC81453 protein.	0.924
A0A1L8GA23	vegt	A0A1L8GA23	A0A1L8HQC9	Chordin; Belongs to the chordin family.	Uncharacterized protein.	0.604