30 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dkk1-2	Dickkopf homolog 1. (259 aa)
	nck1-2	Cytoplasmic protein. (377 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	tbxt-2	MGC81453 protein. (432 aa)
	dkk2-2	Dickkopf homolog 2. (255 aa)
	fzd2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	glb1	Uncharacterized protein; Belongs to the glycosyl hydrolase 35 family. (642 aa)
	prickle3-b	Prickle planar cell polarity protein 3-B; Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (By similarity). PCP is maintained by two molecular modules, the global and the core modules. Proteins of the core module include the proteins Frizzled (Fz), Disheveled (Dsh), Van Gogh (Vang), Prickle (Pk), Flamingo (Fmi, Celsr) and Diego (Dgo). The core module proteins develop subcellular asymmetry, accumulating in two groups on opposite sides of epithelial cells. D [...] (536 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	Glb1l2.S	Beta-galactosidase. (616 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	glb1l2	Beta-galactosidase. (634 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	Glb1l.L	Beta-galactosidase. (645 aa)
	tbxt	Uncharacterized protein. (432 aa)
	prickle2	Uncharacterized protein. (833 aa)
	prickle2-2	Uncharacterized protein. (833 aa)
	Smo.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (814 aa)
	prickle1	Uncharacterized protein. (835 aa)
	Prickle1.L	Uncharacterized protein. (832 aa)
	Smo.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
	nck2	Cytoplasmic protein. (381 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	nck2-2	Cytoplasmic protein. (381 aa)
	A0A1L8HJF4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (456 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	dkk2	Dickkopf_N domain-containing protein. (255 aa)
	nck1	Cytoplasmic protein. (377 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8HJF4	ctnnb1	A0A1L8HJF4	Q63ZT4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Beta-catenin protein.	0.664
A0A1L8HJF4	wnt11	A0A1L8HJF4	A0A1L8HJX1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.911
A0A1L8HJF4	wnt11b	A0A1L8HJF4	A0A1L8F6W4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.910
Fzd4.S	ctnnb1	A0A1L8HB90	Q63ZT4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Beta-catenin protein.	0.871
Fzd4.S	dkk1	A0A1L8HB90	A0A1L8FIS6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf_N domain-containing protein.	0.663
Fzd4.S	dkk1-2	A0A1L8HB90	O57464	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf homolog 1.	0.660
Fzd4.S	dkk2	A0A1L8HB90	A0A1L8HM80	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf_N domain-containing protein.	0.567
Fzd4.S	dkk2-2	A0A1L8HB90	Q9DDA4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf homolog 2.	0.567
Fzd4.S	fzd1	A0A1L8HB90	A0A1L8FVQ7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.413
Fzd4.S	fzd2	A0A1L8HB90	A0A1L8EL29	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.406
Fzd4.S	prickle1	A0A1L8HB90	A0A1L8GUA2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.477
Fzd4.S	prickle2	A0A1L8HB90	A0A1L8GI20	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.441
Fzd4.S	prickle2-2	A0A1L8HB90	A0A1L8GQ36	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.441
Fzd4.S	prickle3-b	A0A1L8HB90	A0A1L8F1M4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Prickle planar cell polarity protein 3-B; Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (By similarity). PCP is maintained by two molecular modules, the global and the core modules. Proteins of the core module include the proteins Frizzled (Fz), Disheveled (Dsh), Van Gogh (Vang), Prickle (Pk), Flamingo (Fmi, Celsr) and Diego (Dgo). The core module proteins develop subcellular asymmetry, accumulating in two groups on opposite sides of epithelial cells. D [...]	0.411
Fzd4.S	wnt11	A0A1L8HB90	A0A1L8HJX1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.969
Fzd4.S	wnt11b	A0A1L8HB90	A0A1L8F6W4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.971
Glb1l.L	glb1	A0A1L8FWQ8	A0A1L8EVM8	Beta-galactosidase.	Uncharacterized protein; Belongs to the glycosyl hydrolase 35 family.	0.902
Prickle1.L	ctnnb1	A0A1L8GYU6	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.654
Prickle1.L	fzd2	A0A1L8GYU6	A0A1L8EL29	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.534
Prickle1.L	nck1	A0A1L8GYU6	P79956	Uncharacterized protein.	Cytoplasmic protein.	0.493