STRINGSTRING
notch1 notch1 Scnn1g.S Scnn1g.S actl6a actl6a rhoa rhoa Smurf1.L Smurf1.L gammaxENaC-A gammaxENaC-A cdh3 cdh3 Notch1.S Notch1.S Cdh3.S Cdh3.S sdhd-2 sdhd-2 sdhd sdhd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
notch1Uncharacterized protein. (2521 aa)
Scnn1g.SUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (673 aa)
actl6aBaf53a-pending-prov protein; Belongs to the actin family. (429 aa)
rhoaMGC64296 protein. (193 aa)
Smurf1.LE3 ubiquitin-protein ligase. (731 aa)
gammaxENaC-AGammaxENaC-A protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (660 aa)
cdh3Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
Notch1.SUncharacterized protein. (2524 aa)
Cdh3.SUncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
sdhd-2Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (152 aa)
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (152 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.