42 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ptpro	Uncharacterized protein. (1289 aa)
	map2k1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (395 aa)
	Rho.L	Rhodopsin. (459 aa)
	Prkacb.S	Uncharacterized protein; Belongs to the protein kinase superfamily. (338 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (396 aa)
	rhoa	MGC64296 protein. (193 aa)
	efnb2	Efnb2a protein; Belongs to the ephrin family. (329 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	vav1	Vav1-prov protein. (845 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	bdnf-2	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
	rac1	MGC114731 protein. (192 aa)
	nck1-2	Cytoplasmic protein. (377 aa)
	src	Tyrosine-protein kinase. (532 aa)
	nck1	Cytoplasmic protein. (377 aa)
	efnb1	Ephrin-B1 (EPH family ligand); Belongs to the ephrin family. (329 aa)
	ntn5-2	LOC100127305 protein. (601 aa)
	pik3c3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
	Prkg2.L	cGMP-dependent protein kinase. (785 aa)
	rac3	RAC1 protein. (192 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	prkaca	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	epha4	Pag protein. (986 aa)
	ntn1	Uncharacterized protein. (602 aa)
	ntn3	Uncharacterized protein. (588 aa)
	ntn1-2	Uncharacterized protein. (602 aa)
	ntn3-2	Uncharacterized protein. (588 aa)
	prkg1	cGMP-dependent protein kinase. (673 aa)
	A0A1L8FF79	cGMP-dependent protein kinase. (763 aa)
	Cxcl12.S	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
	ntn5	Uncharacterized protein. (601 aa)
	A0A1L8FK17	cGMP-dependent protein kinase. (763 aa)
	cxcl12	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (89 aa)
	Epha2.L	Uncharacterized protein. (948 aa)
	Epha4.L	Uncharacterized protein. (1022 aa)
	acp1	LMWPc domain-containing protein. (158 aa)
	bdnf	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
	A0A1L8HTQ2	Uncharacterized protein. (1521 aa)
	Efna5.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (185 aa)
	Slit2.S	Uncharacterized protein. (1530 aa)
	Efnb2.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (329 aa)
	pkn1	Uncharacterized protein. (942 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FF79	Prkacb.S	A0A1L8FF79	A0A1L8GLU4	cGMP-dependent protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.597
A0A1L8FF79	prkaca	A0A1L8FF79	Q90WN3	cGMP-dependent protein kinase.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.598
A0A1L8FF79	prkacb	A0A1L8FF79	A0A1L8GFG6	cGMP-dependent protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.601
A0A1L8FK17	Prkacb.S	A0A1L8FK17	A0A1L8GLU4	cGMP-dependent protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.597
A0A1L8FK17	prkaca	A0A1L8FK17	Q90WN3	cGMP-dependent protein kinase.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.598
A0A1L8FK17	prkacb	A0A1L8FK17	A0A1L8GFG6	cGMP-dependent protein kinase.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.601
A0A1L8HTQ2	Cxcl12.S	A0A1L8HTQ2	A0A1L8FFA8	Uncharacterized protein.	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	0.493
A0A1L8HTQ2	Efna5.S	A0A1L8HTQ2	A0A1L8HR32	Uncharacterized protein.	Ephrin RBD domain-containing protein; Belongs to the ephrin family.	0.521
A0A1L8HTQ2	Epha2.L	A0A1L8HTQ2	A0A1L8FPA0	Uncharacterized protein.	Uncharacterized protein.	0.446
A0A1L8HTQ2	bdnf	A0A1L8HTQ2	A0A1L8GDT3	Uncharacterized protein.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.634
A0A1L8HTQ2	bdnf-2	A0A1L8HTQ2	Q63ZM5	Uncharacterized protein.	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.	0.634
A0A1L8HTQ2	cxcl12	A0A1L8HTQ2	A0A1L8FKT2	Uncharacterized protein.	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	0.492
A0A1L8HTQ2	ntn1	A0A1L8HTQ2	A0A1L8EN54	Uncharacterized protein.	Uncharacterized protein.	0.904
A0A1L8HTQ2	ntn1-2	A0A1L8HTQ2	A0A1L8EV13	Uncharacterized protein.	Uncharacterized protein.	0.903
A0A1L8HTQ2	ntn3	A0A1L8HTQ2	A0A1L8EQL7	Uncharacterized protein.	Uncharacterized protein.	0.904
A0A1L8HTQ2	ntn3-2	A0A1L8HTQ2	A0A1L8EY77	Uncharacterized protein.	Uncharacterized protein.	0.904
A0A1L8HTQ2	ntn5	A0A1L8HTQ2	A0A1L8FGS1	Uncharacterized protein.	Uncharacterized protein.	0.904
A0A1L8HTQ2	ntn5-2	A0A1L8HTQ2	A9JS48	Uncharacterized protein.	LOC100127305 protein.	0.904
A0A1L8HTQ2	rhoa	A0A1L8HTQ2	Q7SZA9	Uncharacterized protein.	MGC64296 protein.	0.537
Cxcl12.S	A0A1L8HTQ2	A0A1L8FFA8	A0A1L8HTQ2	SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.	Uncharacterized protein.	0.493