40 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mst1	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (718 aa)
	ralb	Uncharacterized protein. (206 aa)
	rab5c	Uncharacterized protein. (215 aa)
	ralb-2	Uncharacterized protein. (206 aa)
	sos2	Uncharacterized protein. (1335 aa)
	ralgds	Uncharacterized protein. (835 aa)
	sos2-2	Uncharacterized protein. (1332 aa)
	Rab5a.L	Uncharacterized protein. (216 aa)
	sos1	Uncharacterized protein. (1325 aa)
	A0A1L8G4B9	Profilin; Belongs to the profilin family. (126 aa)
	Pfn4.S	Profilin; Belongs to the profilin family. (172 aa)
	cenpf	Uncharacterized protein. (2607 aa)
	plek	Uncharacterized protein. (350 aa)
	sos1-2	Uncharacterized protein. (1325 aa)
	rce1	Uncharacterized protein. (310 aa)
	Ccne1.S	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
	Mst1.S	Uncharacterized protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (716 aa)
	ccne1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (408 aa)
	rassf1	Uncharacterized protein. (369 aa)
	rassf2	Uncharacterized protein. (320 aa)
	Rassf3.S	Uncharacterized protein. (250 aa)
	mdm2	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa)
	rassf5	Uncharacterized protein. (252 aa)
	Nf1.S	Uncharacterized protein. (2774 aa)
	nras	Uncharacterized protein. (189 aa)
	rassf5-2	Uncharacterized protein. (252 aa)
	nf1	Uncharacterized protein. (2759 aa)
	Egf.L	Uncharacterized protein. (1031 aa)
	cenpe	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (3316 aa)
	PIK3R1	Phosphoinositide-3-kinase. (722 aa)
	src	Tyrosine-protein kinase. (532 aa)
	rhob	MGC131029 protein. (196 aa)
	pfn1	Profilin; Belongs to the profilin family. (138 aa)
	rabif	MGC115104 protein. (118 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	rassf2-2	Rassf4 protein. (320 aa)
	pfn2	Profilin; Belongs to the profilin family. (140 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	tert	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1191 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8G4B9	actl6a	A0A1L8G4B9	Q7ZYI5	Profilin; Belongs to the profilin family.	Baf53a-pending-prov protein; Belongs to the actin family.	0.987
A0A1L8G4B9	rhob	A0A1L8G4B9	Q2TAR5	Profilin; Belongs to the profilin family.	MGC131029 protein.	0.466
Ccne1.S	actl6a	A0A1L8GF58	Q7ZYI5	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Baf53a-pending-prov protein; Belongs to the actin family.	0.634
Ccne1.S	mdm2	A0A1L8GF58	A0A1L8GYI7	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.	0.511
Ccne1.S	src	A0A1L8GF58	Q2TAR1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Tyrosine-protein kinase.	0.488
Ccne1.S	tert	A0A1L8GF58	Q9DE32	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.584
Egf.L	PIK3R1	A0A1L8HUT3	B7ZRD8	Uncharacterized protein.	Phosphoinositide-3-kinase.	0.601
Egf.L	Ptpn11.S	A0A1L8HUT3	Q92124	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.688
Egf.L	actl6a	A0A1L8HUT3	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.636
Egf.L	nras	A0A1L8HUT3	A0A1L8HE10	Uncharacterized protein.	Uncharacterized protein.	0.540
Egf.L	plek	A0A1L8HUT3	A0A1L8G6R7	Uncharacterized protein.	Uncharacterized protein.	0.414
Egf.L	ptpn11b	A0A1L8HUT3	Q6GP31	Uncharacterized protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.688
Egf.L	ralb	A0A1L8HUT3	A0A1L8ENH3	Uncharacterized protein.	Uncharacterized protein.	0.449
Egf.L	ralb-2	A0A1L8HUT3	A0A1L8EVG4	Uncharacterized protein.	Uncharacterized protein.	0.449
Egf.L	sos1	A0A1L8HUT3	A0A1L8G1Z8	Uncharacterized protein.	Uncharacterized protein.	0.662
Egf.L	sos1-2	A0A1L8HUT3	A0A1L8G7X8	Uncharacterized protein.	Uncharacterized protein.	0.662
Egf.L	sos2	A0A1L8HUT3	A0A1L8F088	Uncharacterized protein.	Uncharacterized protein.	0.543
Egf.L	sos2-2	A0A1L8HUT3	A0A1L8F9P9	Uncharacterized protein.	Uncharacterized protein.	0.543
Egf.L	src	A0A1L8HUT3	Q2TAR1	Uncharacterized protein.	Tyrosine-protein kinase.	0.802
Egf.L	tert	A0A1L8HUT3	Q9DE32	Uncharacterized protein.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.570