41 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nubp1	Cytosolic Fe-S cluster assembly factor nubp1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (315 aa)
	Frzb.S	Uncharacterized protein. (319 aa)
	bmp4-2	Bone morphogenetic protein 4. (400 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
	sfrp2-2	Sfrp2-prov protein. (298 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	xfz8	Frizzled-8; Belongs to the G-protein coupled receptor Fz/Smo family. (583 aa)
	fz3	Fz3 protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	fzd10a	Frizzled 10A; Belongs to the G-protein coupled receptor Fz/Smo family. (586 aa)
	Xwnt-8b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
	LOC397855	Beta-1,3-N-acetylglucosaminyltransferase. (375 aa)
	bmp4	Bone morphogenetic protein 4. (401 aa)
	wnt6-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	msx1-2	LOC100125666 protein. (273 aa)
	sfrp2	Uncharacterized protein. (295 aa)
	fzd10	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
	msx1	Homeobox domain-containing protein. (275 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Sfrp1.L	Uncharacterized protein. (311 aa)
	sfrp1	Uncharacterized protein. (311 aa)
	Wnt5b.S	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
	fzd3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (664 aa)
	fzd6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (724 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	Fzd8.L	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Wnt9a.S	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (528 aa)
	Fzd6.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
	wnt4-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	Lfng.L	Beta-1,3-N-acetylglucosaminyltransferase. (373 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	Frzb-1	Uncharacterized protein. (319 aa)
	wnt6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Frzb-1	Sfrp1.L	A0A1L8EWF4	A0A1L8H1S5	Uncharacterized protein.	Uncharacterized protein.	0.410
Frzb-1	Wnt1.L	A0A1L8EWF4	A0A1L8HHR8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.834
Frzb-1	Wnt5b.S	A0A1L8EWF4	A0A1L8GQS0	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.650
Frzb-1	Wnt9a.S	A0A1L8EWF4	A0A1L8FUX2	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.650
Frzb-1	Xwnt-8b	A0A1L8EWF4	B7ZQM6	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.589
Frzb-1	bmp4	A0A1L8EWF4	B7ZPR8	Uncharacterized protein.	Bone morphogenetic protein 4.	0.482
Frzb-1	bmp4-2	A0A1L8EWF4	Q91703	Uncharacterized protein.	Bone morphogenetic protein 4.	0.479
Frzb-1	ctnnb1	A0A1L8EWF4	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.777
Frzb-1	dkk1	A0A1L8EWF4	A0A1L8FIS6	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.855
Frzb-1	dkk1-2	A0A1L8EWF4	O57464	Uncharacterized protein.	Dickkopf homolog 1.	0.872
Frzb-1	sfrp2	A0A1L8EWF4	A0A1L8HUI3	Uncharacterized protein.	Uncharacterized protein.	0.441
Frzb-1	sfrp2-2	A0A1L8EWF4	Q7ZXM6	Uncharacterized protein.	Sfrp2-prov protein.	0.447
Frzb-1	wnt1	A0A1L8EWF4	A0A1L8H9S8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.834
Frzb-1	wnt11	A0A1L8EWF4	A0A1L8HJX1	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.761
Frzb-1	wnt11b	A0A1L8EWF4	A0A1L8F6W4	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.768
Frzb-1	wnt3a	A0A1L8EWF4	A0A1L8FUX8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.725
Frzb-1	wnt4	A0A1L8EWF4	A0A1L8FG99	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.624
Frzb-1	wnt4-2	A0A1L8EWF4	A0A1L8FM93	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.624
Frzb-1	wnt6	A0A1L8EWF4	A0A1L8EVQ7	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.584
Frzb-1	wnt6-2	A0A1L8EWF4	B0FK91	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.591