STRINGSTRING
Rad17.L Rad17.L Chek2.L Chek2.L ptch1 ptch1 Gli1.L Gli1.L gli1 gli1 Smo.L Smo.L Cdc25c1 Cdc25c1 Smo.S Smo.S Rad26 Rad26 atrip atrip A0A1L8G795 A0A1L8G795 A0A1L8G6S1 A0A1L8G6S1 A0A1L8G6R5 A0A1L8G6R5 H2B-2 H2B-2 topbp1 topbp1 Shh.L Shh.L h2ax h2ax A0A1L8FQA5 A0A1L8FQA5 Cdc25a.S Cdc25a.S A0A1L8FQ56 A0A1L8FQ56 A0A1L8ENU1 A0A1L8ENU1 chek1 chek1 chek1-2 chek1-2 A0A1L8FQM4 A0A1L8FQM4 ptch1-2 ptch1-2 H2B H2B Hus1 Hus1 rad9a rad9a Clspn.S Clspn.S Hist2h2ab.S Hist2h2ab.S A0A310U368 A0A310U368 A0A310TM08 A0A310TM08 pik3c3 pik3c3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Rad17.LUncharacterized protein. (674 aa)
Chek2.LUncharacterized protein. (392 aa)
ptch1SSD domain-containing protein. (1422 aa)
Gli1.LUncharacterized protein. (1362 aa)
gli1Uncharacterized protein. (1361 aa)
Smo.LUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (815 aa)
Cdc25c1Rhodanese domain-containing protein. (550 aa)
Smo.SUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (814 aa)
Rad26Uncharacterized protein. (798 aa)
atripUncharacterized protein. (801 aa)
A0A1L8G795Histone H2B; Belongs to the histone H2B family. (126 aa)
A0A1L8G6S1Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (238 aa)
A0A1L8G6R5Histone H2B; Belongs to the histone H2B family. (347 aa)
H2B-2Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (233 aa)
topbp1Uncharacterized protein. (1573 aa)
Shh.LHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
h2axHistone H2A; Belongs to the histone H2A family. (139 aa)
A0A1L8FQA5Histone H2B; Belongs to the histone H2B family. (126 aa)
Cdc25a.SRhodanese domain-containing protein. (172 aa)
A0A1L8FQ56Histone H2B; Belongs to the histone H2B family. (126 aa)
A0A1L8ENU1Uncharacterized protein; Belongs to the histone H2B family. (98 aa)
chek1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
chek1-2Protein kinase domain-containing protein. (510 aa)
A0A1L8FQM4Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
ptch1-2Patched-1. (1418 aa)
H2BHistone H2B; Belongs to the histone H2B family. (126 aa)
Hus1Checkpoint protein; Belongs to the HUS1 family. (282 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
Clspn.SClaspin. (1286 aa)
Hist2h2ab.SHistone H2A; Belongs to the histone H2A family. (139 aa)
A0A310U368Histone H2B; Belongs to the histone H2B family. (94 aa)
A0A310TM08Histone H2B; Belongs to the histone H2B family. (126 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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