27 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fos	BZIP domain-containing protein. (369 aa)
	egfr	Receptor protein-tyrosine kinase. (1208 aa)
	cdh2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (947 aa)
	Zeb1.S	Uncharacterized protein. (919 aa)
	egfr-2	Receptor protein-tyrosine kinase. (1210 aa)
	Esr1.S	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	cdh5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (774 aa)
	cdh5-2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (775 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	tnf-2	Tumor necrosis factor alpha. (225 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	esr1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (585 aa)
	stat5b	Signal transducer and activator of transcription. (781 aa)
	fos-2	MGC80305 protein. (368 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	src	Tyrosine-protein kinase. (532 aa)
	cdh11-2	Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	vegfa	Vascular endothelial growth factor 196; Belongs to the PDGF/VEGF growth factor family. (194 aa)
	pard6b	Uncharacterized protein. (377 aa)
	Llgl1.S	WD_REPEATS_REGION domain-containing protein. (999 aa)
	Axin1.S	Uncharacterized protein. (839 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	A0A1L8EYQ3	LLGL domain-containing protein. (1049 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EYQ3	Cdh3.S	A0A1L8EYQ3	A0A1L8GET9	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.479
A0A1L8EYQ3	Prkci.L	A0A1L8EYQ3	A0A1L8GAK2	LLGL domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.992
A0A1L8EYQ3	actl6a	A0A1L8EYQ3	Q7ZYI5	LLGL domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.439
A0A1L8EYQ3	cdh1	A0A1L8EYQ3	A0A1L8GKV4	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.428
A0A1L8EYQ3	cdh11-2	A0A1L8EYQ3	O93264	LLGL domain-containing protein.	Cadherin; Cadherins are calcium-dependent cell adhesion proteins.	0.437
A0A1L8EYQ3	cdh3	A0A1L8EYQ3	A0A1L8GKW6	LLGL domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.473
A0A1L8EYQ3	pard6b	A0A1L8EYQ3	A0A1L8ELH2	LLGL domain-containing protein.	Uncharacterized protein.	0.957
A0A1L8EYQ3	pard6b-2	A0A1L8EYQ3	A0A1L8ESP6	LLGL domain-containing protein.	Uncharacterized protein.	0.957
Axin1.S	Cdh3.S	A0A1L8ER48	A0A1L8GET9	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.796
Axin1.S	Tp53.L	A0A1L8ER48	A0A1L8H4M6	Uncharacterized protein.	P53 domain-containing protein.	0.679
Axin1.S	actl6a	A0A1L8ER48	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.715
Axin1.S	cdh1	A0A1L8ER48	A0A1L8GKV4	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.795
Axin1.S	cdh11-2	A0A1L8ER48	O93264	Uncharacterized protein.	Cadherin; Cadherins are calcium-dependent cell adhesion proteins.	0.758
Axin1.S	cdh2	A0A1L8ER48	A0A1L8FSZ9	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.472
Axin1.S	cdh3	A0A1L8ER48	A0A1L8GKW6	Uncharacterized protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.801
Axin1.S	ctnnb1	A0A1L8ER48	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.999
Axin1.S	egfr	A0A1L8ER48	A0A1L8FRS8	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.428
Axin1.S	egfr-2	A0A1L8ER48	A0A1L8FWP8	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.428
Axin1.S	src	A0A1L8ER48	Q2TAR1	Uncharacterized protein.	Tyrosine-protein kinase.	0.576
Cdh3.S	A0A1L8EYQ3	A0A1L8GET9	A0A1L8EYQ3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	LLGL domain-containing protein.	0.479