14 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Brca1.L	Uncharacterized protein. (1582 aa)
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	Nbn.L	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (762 aa)
	Atr.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2654 aa)
	atrip	Uncharacterized protein. (801 aa)
	Rad26	Uncharacterized protein. (798 aa)
	rad50	Zinc-hook domain-containing protein. (1311 aa)
	rad50-2	Zinc-hook domain-containing protein. (1312 aa)
	Tp53.L	P53 domain-containing protein. (137 aa)
	PIK3R1	Phosphoinositide-3-kinase. (722 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atr.L	Brca1.L	A0A1L8GAP7	A0A1L8ETS4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.998
Atr.L	Hus1	A0A1L8GAP7	Q8JHD8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Checkpoint protein; Belongs to the HUS1 family.	0.999
Atr.L	Nbn.L	A0A1L8GAP7	A0A1L8FZE8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	0.990
Atr.L	Rad26	A0A1L8GAP7	A0A1L8GP12	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999
Atr.L	Tp53.L	A0A1L8GAP7	A0A1L8H4M6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	P53 domain-containing protein.	0.991
Atr.L	atrip	A0A1L8GAP7	A0A1L8GH95	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999
Atr.L	chek1	A0A1L8GAP7	A0A1L8FFS1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.999
Atr.L	chek1-2	A0A1L8GAP7	A0A1L8FL95	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.999
Atr.L	rad50	A0A1L8GAP7	A0A1L8GVF0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Zinc-hook domain-containing protein.	0.955
Atr.L	rad50-2	A0A1L8GAP7	A0A1L8GXM0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Zinc-hook domain-containing protein.	0.955
Atr.L	rad9a	A0A1L8GAP7	Q7ZZU5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.998
Atr.L	topbp1	A0A1L8GAP7	A0A1L8FWJ6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999
Brca1.L	Atr.L	A0A1L8ETS4	A0A1L8GAP7	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.998
Brca1.L	Hus1	A0A1L8ETS4	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.885
Brca1.L	Nbn.L	A0A1L8ETS4	A0A1L8FZE8	Uncharacterized protein.	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	0.996
Brca1.L	Rad26	A0A1L8ETS4	A0A1L8GP12	Uncharacterized protein.	Uncharacterized protein.	0.959
Brca1.L	Tp53.L	A0A1L8ETS4	A0A1L8H4M6	Uncharacterized protein.	P53 domain-containing protein.	0.994
Brca1.L	atrip	A0A1L8ETS4	A0A1L8GH95	Uncharacterized protein.	Uncharacterized protein.	0.959
Brca1.L	chek1	A0A1L8ETS4	A0A1L8FFS1	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.980
Brca1.L	chek1-2	A0A1L8ETS4	A0A1L8FL95	Uncharacterized protein.	Protein kinase domain-containing protein.	0.980