STRINGSTRING
klf9 klf9 ngf ngf Lrp1.S Lrp1.S ccl5 ccl5 Ngf.L Ngf.L kdr kdr tek tek cdkn2b cdkn2b smad7 smad7 pxn pxn smad6 smad6 bmp4 bmp4 LOC100189571 LOC100189571 mapk14 mapk14 vegfa vegfa smad7-2 smad7-2 smad6-2 smad6-2 cdkn2b-2 cdkn2b-2 src src sdc2-2 sdc2-2 ccn2 ccn2 ptpn11b ptpn11b rhoa rhoa dstn dstn actl6a actl6a ccnd1 ccnd1 Serpine1.L Serpine1.L bmp4-2 bmp4-2 Ptpn11.S Ptpn11.S pxn-2 pxn-2 bmp7.1-2 bmp7.1-2 timp-1 timp-1 bmp7.1 bmp7.1 Fn1.S Fn1.S Cfl2.S Cfl2.S tgfb1 tgfb1 Cdk20.S Cdk20.S tgfb1-2 tgfb1-2 cfl2 cfl2 prkcz prkcz sdc2 sdc2 pik3cb pik3cb A0A1L8G7I3 A0A1L8G7I3 pik3cb-2 pik3cb-2 cfl1 cfl1 Mmp2.S Mmp2.S Nphs2.S Nphs2.S Cfl1.L Cfl1.L nphs2 nphs2 A0A1L8GQT6 A0A1L8GQT6 Cdkn1b.S Cdkn1b.S pik3cg pik3cg Bmp7.2.L Bmp7.2.L plat plat
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
klf9Basic transcription element binding protein 1. (292 aa)
ngfNGF domain-containing protein; Belongs to the NGF-beta family. (242 aa)
Lrp1.SUncharacterized protein. (4544 aa)
ccl5SCY domain-containing protein. (93 aa)
Ngf.LNGF domain-containing protein; Belongs to the NGF-beta family. (232 aa)
kdrUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1326 aa)
tekUncharacterized protein. (1126 aa)
cdkn2bANK_REP_REGION domain-containing protein. (125 aa)
smad7Mothers against decapentaplegic homolog. (382 aa)
pxnUncharacterized protein; Belongs to the paxillin family. (542 aa)
smad6Mothers against decapentaplegic homolog. (352 aa)
bmp4Bone morphogenetic protein 4. (401 aa)
LOC100189571Uncharacterized protein. (608 aa)
mapk14Mitogen-activated protein kinase. (361 aa)
vegfaVascular endothelial growth factor 196; Belongs to the PDGF/VEGF growth factor family. (194 aa)
smad7-2Mothers against decapentaplegic homolog. (382 aa)
smad6-2Mothers against decapentaplegic homolog. (354 aa)
cdkn2b-2MGC154405 protein. (125 aa)
srcTyrosine-protein kinase. (532 aa)
sdc2-2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (191 aa)
ccn2Ctgf protein. (343 aa)
ptpn11bTyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
rhoaMGC64296 protein. (193 aa)
dstnMGC53245 protein; Belongs to the actin-binding proteins ADF family. (153 aa)
actl6aBaf53a-pending-prov protein; Belongs to the actin family. (429 aa)
ccnd1Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
Serpine1.LSERPIN domain-containing protein; Belongs to the serpin family. (403 aa)
bmp4-2Bone morphogenetic protein 4. (400 aa)
Ptpn11.STyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
pxn-2LOC397826 protein; Belongs to the paxillin family. (539 aa)
bmp7.1-2Osteogenic protein-1 homolog. (424 aa)
timp-1Tissue inhibitor of metalloproteinase-1. (216 aa)
bmp7.1TGF_BETA_2 domain-containing protein. (424 aa)
Fn1.SUncharacterized protein. (2480 aa)
Cfl2.SADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (310 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
Cdk20.SProtein kinase domain-containing protein. (376 aa)
tgfb1-2Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
cfl2ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (167 aa)
prkczProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (590 aa)
sdc2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (190 aa)
pik3cbUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
A0A1L8G7I3ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (153 aa)
pik3cb-2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
cfl1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (168 aa)
Mmp2.SUncharacterized protein. (656 aa)
Nphs2.SPHB domain-containing protein. (370 aa)
Cfl1.LADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (292 aa)
nphs2PHB domain-containing protein. (375 aa)
A0A1L8GQT6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
Cdkn1b.SUncharacterized protein. (152 aa)
pik3cgUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
Bmp7.2.LTGF_BETA_2 domain-containing protein. (438 aa)
platPlasminogen activator; Belongs to the peptidase S1 family. (566 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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