14 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	Clspn.S	Claspin. (1286 aa)
	cdc45	Uncharacterized protein. (567 aa)
	Cdk2.S	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
	Mrc1.L	C-type lectin domain-containing protein. (220 aa)
	tipin	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (362 aa)
	Cdc25c1	Rhodanese domain-containing protein. (550 aa)
	Tipin.S	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (361 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	Cdc25a.S	Rhodanese domain-containing protein. (172 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdc25a.S	Cdk2.S	A0A1L8FQA3	A0A1L8H9N1	Rhodanese domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.995
Cdc25a.S	Clspn.S	A0A1L8FQA3	F8WKR8	Rhodanese domain-containing protein.	Claspin.	0.756
Cdc25a.S	Hus1	A0A1L8FQA3	Q8JHD8	Rhodanese domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.523
Cdc25a.S	cdc45	A0A1L8FQA3	A0A1L8I0M4	Rhodanese domain-containing protein.	Uncharacterized protein.	0.647
Cdc25a.S	chek1	A0A1L8FQA3	A0A1L8FFS1	Rhodanese domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.995
Cdc25a.S	chek1-2	A0A1L8FQA3	A0A1L8FL95	Rhodanese domain-containing protein.	Protein kinase domain-containing protein.	0.995
Cdc25a.S	rad9a	A0A1L8FQA3	Q7ZZU5	Rhodanese domain-containing protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.530
Cdc25a.S	topbp1	A0A1L8FQA3	A0A1L8FWJ6	Rhodanese domain-containing protein.	Uncharacterized protein.	0.571
Cdc25c1	Cdk2.S	A0A1L8GUV6	A0A1L8H9N1	Rhodanese domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.997
Cdc25c1	Clspn.S	A0A1L8GUV6	F8WKR8	Rhodanese domain-containing protein.	Claspin.	0.774
Cdc25c1	Hus1	A0A1L8GUV6	Q8JHD8	Rhodanese domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.526
Cdc25c1	cdc45	A0A1L8GUV6	A0A1L8I0M4	Rhodanese domain-containing protein.	Uncharacterized protein.	0.698
Cdc25c1	chek1	A0A1L8GUV6	A0A1L8FFS1	Rhodanese domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.998
Cdc25c1	chek1-2	A0A1L8GUV6	A0A1L8FL95	Rhodanese domain-containing protein.	Protein kinase domain-containing protein.	0.998
Cdc25c1	rad9a	A0A1L8GUV6	Q7ZZU5	Rhodanese domain-containing protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.535
Cdc25c1	topbp1	A0A1L8GUV6	A0A1L8FWJ6	Rhodanese domain-containing protein.	Uncharacterized protein.	0.606
Cdk2.S	Cdc25a.S	A0A1L8H9N1	A0A1L8FQA3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Rhodanese domain-containing protein.	0.995
Cdk2.S	Cdc25c1	A0A1L8H9N1	A0A1L8GUV6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Rhodanese domain-containing protein.	0.997
Cdk2.S	Clspn.S	A0A1L8H9N1	F8WKR8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Claspin.	0.794
Cdk2.S	Hus1	A0A1L8H9N1	Q8JHD8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Checkpoint protein; Belongs to the HUS1 family.	0.606