(23 nodes) (2009) Slc26a9--anion exchanger, channel and Na+ transporter. network (Xenopus laevis)

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proteins of unknown 3D structure

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Your Input:
	Wnk1.S	Uncharacterized protein. (265 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	Gapdh.S	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	slc26a1	Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (719 aa)
	elk4	MGC82106 protein. (405 aa)
	ctse-2	Cathepsin E1; Belongs to the peptidase A1 family. (397 aa)
	slc4a4-2	Anion exchange protein. (1082 aa)
	slc4a4	Anion exchange protein. (1082 aa)
	Cdk18.L	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (466 aa)
	ctse	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (397 aa)
	cdk18	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (466 aa)
	Mdm4.S	RanBP2-type domain-containing protein. (423 aa)
	slc26a4.3	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (778 aa)
	slc26a5-2	STAS domain-containing protein. (752 aa)
	cftr-2	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa)
	slc26a2	Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (713 aa)
	slc26a2.2	STAS domain-containing protein. (745 aa)
	A0A1L8GUF3	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (402 aa)
	cftr	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1483 aa)
	Slc26a4.S	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (778 aa)
	slc26a5	STAS domain-containing protein. (754 aa)
	wnk4-2	Protein kinase domain-containing protein. (1575 aa)
	wnk4	Protein kinase domain-containing protein. (1573 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GUF3	Cdk18.L	A0A1L8GUF3	A0A1L8HEU5	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.643
A0A1L8GUF3	cdk18	A0A1L8GUF3	A0A1L8H715	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.558
A0A1L8GUF3	elk4	A0A1L8GUF3	Q6GM77	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	MGC82106 protein.	0.478
Cdk18.L	A0A1L8GUF3	A0A1L8HEU5	A0A1L8GUF3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.643
Cdk18.L	Mdm4.S	A0A1L8HEU5	A0A1L8H6P1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	RanBP2-type domain-containing protein.	0.437
Cdk18.L	ctse	A0A1L8HEU5	A0A1L8H7D5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family.	0.553
Cdk18.L	ctse-2	A0A1L8HEU5	B7ZQ61	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Cathepsin E1; Belongs to the peptidase A1 family.	0.546
Cdk18.L	elk4	A0A1L8HEU5	Q6GM77	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	MGC82106 protein.	0.550
Gapdh.S	gapdh	Q7ZY52	Q8AY70	Glyceraldehyde-3-phosphate dehydrogenase.	Glyceraldehyde-3-phosphate dehydrogenase.	0.900
Mdm4.S	Cdk18.L	A0A1L8H6P1	A0A1L8HEU5	RanBP2-type domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.437
Mdm4.S	elk4	A0A1L8H6P1	Q6GM77	RanBP2-type domain-containing protein.	MGC82106 protein.	0.465
Slc26a4.S	Wnk1.S	A0A1L8GTZ1	A0A1L8GQQ4	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	Uncharacterized protein.	0.493
Slc26a4.S	cftr	A0A1L8GTZ1	A0A1L8GU84	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.759
Slc26a4.S	cftr-2	A0A1L8GTZ1	A0A1L8GYY2	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.758
Slc26a4.S	slc4a4	A0A1L8GTZ1	A0A1L8HMH4	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	Anion exchange protein.	0.691
Slc26a4.S	slc4a4-2	A0A1L8GTZ1	A0A1L8HVC4	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	Anion exchange protein.	0.691
Slc26a4.S	wnk4	A0A1L8GTZ1	A0A1L8EMC7	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	Protein kinase domain-containing protein.	0.540
Slc26a4.S	wnk4-2	A0A1L8GTZ1	A0A1L8ETQ6	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	Protein kinase domain-containing protein.	0.540
Wnk1.S	Slc26a4.S	A0A1L8GQQ4	A0A1L8GTZ1	Uncharacterized protein.	Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	0.493
Wnk1.S	cftr	A0A1L8GQQ4	A0A1L8GU84	Uncharacterized protein.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.477