65 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ptk2b	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1013 aa)
	Lox.L	Uncharacterized protein. (457 aa)
	pxn	Uncharacterized protein; Belongs to the paxillin family. (542 aa)
	vldlr	Uncharacterized protein. (894 aa)
	pdgfra-2	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1087 aa)
	lox	Uncharacterized protein. (422 aa)
	pdgfra	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1090 aa)
	A0A1L8HJ91	FERM domain-containing protein. (557 aa)
	Crk.L	Uncharacterized protein. (297 aa)
	rdx	FERM domain-containing protein. (602 aa)
	Efnb2.S	Ephrin RBD domain-containing protein; Belongs to the ephrin family. (329 aa)
	crk	Uncharacterized protein. (297 aa)
	dock5	Uncharacterized protein; Belongs to the DOCK family. (1842 aa)
	reln	Uncharacterized protein. (3461 aa)
	Dpysl3.S	Amidohydro-rel domain-containing protein. (571 aa)
	dock2	Uncharacterized protein; Belongs to the DOCK family. (1833 aa)
	pik3cg	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
	Wee2	Wee1-like protein kinase. (534 aa)
	dab1	PID domain-containing protein. (561 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	Wee1.S	Wee1-like protein kinase. (595 aa)
	ptk2b-2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1014 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	Irs1.S	Uncharacterized protein. (1227 aa)
	fyn	Tyrosine-protein kinase. (537 aa)
	sos1-2	Uncharacterized protein. (1325 aa)
	xpo1	Importin N-terminal domain-containing protein. (1071 aa)
	plek	Uncharacterized protein. (350 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	sos1	Uncharacterized protein. (1325 aa)
	Bcl2.S	BH4_2 domain-containing protein. (253 aa)
	grb2	Uncharacterized protein. (229 aa)
	grb2-2	Uncharacterized protein. (229 aa)
	sos2	Uncharacterized protein. (1335 aa)
	A0A1L8F270	FERM domain-containing protein. (580 aa)
	sos2-2	Uncharacterized protein. (1332 aa)
	Rap1gap.S	Rap-GAP domain-containing protein. (785 aa)
	sftpa1	C-type lectin domain-containing protein. (183 aa)
	cbl	Uncharacterized protein. (887 aa)
	Rap1gap.L	Uncharacterized protein. (72 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	pxn-2	LOC397826 protein; Belongs to the paxillin family. (539 aa)
	Ptpn11.S	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	efnb2	Efnb2a protein; Belongs to the ephrin family. (329 aa)
	rhog	MGC68933 protein. (191 aa)
	elmo2	MGC68475 protein. (732 aa)
	stat5b	Signal transducer and activator of transcription. (781 aa)
	crkl-2	MGC81407 protein. (302 aa)
	xpo1-2	Xpo1 protein. (1071 aa)
	rap1a	MGC80662 protein. (185 aa)
	ptpn11b	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	zap70	Tyrosine-protein kinase. (617 aa)
	gab1	MGC81548 protein. (691 aa)
	crkl	MGC84382 protein. (302 aa)
	rac1	MGC114731 protein. (192 aa)
	elmo1	MGC114811 protein. (727 aa)
	nck1-2	Cytoplasmic protein. (377 aa)
	src	Tyrosine-protein kinase. (532 aa)
	nck1	Cytoplasmic protein. (377 aa)
	cdh11-2	Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	fyn-2	Tyrosine-protein kinase. (537 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F270	A0A1L8HJ91	A0A1L8F270	A0A1L8HJ91	FERM domain-containing protein.	FERM domain-containing protein.	0.957
A0A1L8F270	Cdh3.S	A0A1L8F270	A0A1L8GET9	FERM domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.501
A0A1L8F270	Crk.L	A0A1L8F270	A0A1L8HDP2	FERM domain-containing protein.	Uncharacterized protein.	0.493
A0A1L8F270	actl6a	A0A1L8F270	Q7ZYI5	FERM domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.978
A0A1L8F270	cdh1	A0A1L8F270	A0A1L8GKV4	FERM domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.500
A0A1L8F270	cdh11-2	A0A1L8F270	O93264	FERM domain-containing protein.	Cadherin; Cadherins are calcium-dependent cell adhesion proteins.	0.445
A0A1L8F270	cdh3	A0A1L8F270	A0A1L8GKW6	FERM domain-containing protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.499
A0A1L8F270	crk	A0A1L8F270	A0A1L8H629	FERM domain-containing protein.	Uncharacterized protein.	0.493
A0A1L8F270	grb2	A0A1L8F270	A0A1L8EMZ6	FERM domain-containing protein.	Uncharacterized protein.	0.437
A0A1L8F270	grb2-2	A0A1L8F270	A0A1L8EUF2	FERM domain-containing protein.	Uncharacterized protein.	0.438
A0A1L8F270	plek	A0A1L8F270	A0A1L8G6R7	FERM domain-containing protein.	Uncharacterized protein.	0.567
A0A1L8F270	pxn	A0A1L8F270	A0A1L8I058	FERM domain-containing protein.	Uncharacterized protein; Belongs to the paxillin family.	0.704
A0A1L8F270	pxn-2	A0A1L8F270	Q9I957	FERM domain-containing protein.	LOC397826 protein; Belongs to the paxillin family.	0.703
A0A1L8F270	rac1	A0A1L8F270	Q58E25	FERM domain-containing protein.	MGC114731 protein.	0.636
A0A1L8F270	rdx	A0A1L8F270	A0A1L8HAW1	FERM domain-containing protein.	FERM domain-containing protein.	0.957
A0A1L8F270	rhog	A0A1L8F270	Q6PCJ6	FERM domain-containing protein.	MGC68933 protein.	0.426
A0A1L8F270	src	A0A1L8F270	Q2TAR1	FERM domain-containing protein.	Tyrosine-protein kinase.	0.525
A0A1L8HJ91	A0A1L8F270	A0A1L8HJ91	A0A1L8F270	FERM domain-containing protein.	FERM domain-containing protein.	0.957
A0A1L8HJ91	actl6a	A0A1L8HJ91	Q7ZYI5	FERM domain-containing protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.895
A0A1L8HJ91	plek	A0A1L8HJ91	A0A1L8G6R7	FERM domain-containing protein.	Uncharacterized protein.	0.691