22 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rad26	Uncharacterized protein. (798 aa)
	atmin	C2H2-type domain-containing protein. (760 aa)
	Kat5.L	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (508 aa)
	atrip	Uncharacterized protein. (801 aa)
	Atr.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2654 aa)
	Prkdc.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4146 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	mlst8	WD_REPEATS_REGION domain-containing protein. (327 aa)
	Smg1.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3654 aa)
	trrap	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3838 aa)
	smg1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3654 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	rfc4	Replication factor C p37 subunit. (363 aa)
	PIK3R1	Phosphoinositide-3-kinase. (722 aa)
	Rad17.L	Uncharacterized protein. (674 aa)
	A0A1L8HTA9	Uncharacterized protein. (3120 aa)
	Rfc2.L	AAA domain-containing protein. (359 aa)
	Rpa1.L	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (609 aa)
	rad50-2	Zinc-hook domain-containing protein. (1312 aa)
	rad50	Zinc-hook domain-containing protein. (1311 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8HTA9	Prkdc.L	A0A1L8HTA9	A0A1L8FYZ4	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.719
A0A1L8HTA9	Smg1.L	A0A1L8HTA9	A0A1L8EXP0	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.578
A0A1L8HTA9	smg1	A0A1L8HTA9	A0A1L8EQ71	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.577
A0A1L8HTA9	trrap	A0A1L8HTA9	A0A1L8EQF0	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.722
Atr.L	Hus1	A0A1L8GAP7	Q8JHD8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Checkpoint protein; Belongs to the HUS1 family.	0.999
Atr.L	Kat5.L	A0A1L8GAP7	A0A1L8GK03	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.568
Atr.L	Prkdc.L	A0A1L8GAP7	A0A1L8FYZ4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.552
Atr.L	Rad17.L	A0A1L8GAP7	A0A1L8I1Y0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.991
Atr.L	Rad26	A0A1L8GAP7	A0A1L8GP12	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999
Atr.L	Rfc2.L	A0A1L8GAP7	A0A1L8HGA4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	AAA domain-containing protein.	0.948
Atr.L	Rpa1.L	A0A1L8GAP7	A0A1L8HDB4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.993
Atr.L	Smg1.L	A0A1L8GAP7	A0A1L8EXP0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.517
Atr.L	atrip	A0A1L8GAP7	A0A1L8GH95	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999
Atr.L	pcna	A0A1L8GAP7	Q9I893	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.743
Atr.L	rad50	A0A1L8GAP7	A0A1L8GVF0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Zinc-hook domain-containing protein.	0.955
Atr.L	rad50-2	A0A1L8GAP7	A0A1L8GXM0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Zinc-hook domain-containing protein.	0.955
Atr.L	rad9a	A0A1L8GAP7	Q7ZZU5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.998
Atr.L	rfc4	A0A1L8GAP7	Q76LD2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Replication factor C p37 subunit.	0.957
Atr.L	smg1	A0A1L8GAP7	A0A1L8EQ71	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.517
Atr.L	topbp1	A0A1L8GAP7	A0A1L8FWJ6	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999