20 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)
	rfc5	Rfc5-prov protein. (335 aa)
	rfc4	Replication factor C p37 subunit. (363 aa)
	rfc3	MGC115007 protein. (356 aa)
	Clspn.S	Claspin. (1286 aa)
	Chek2.L	Uncharacterized protein. (392 aa)
	Xpa.L	XPA_C domain-containing protein. (265 aa)
	Rfc2.L	AAA domain-containing protein. (359 aa)
	rad50-2	Zinc-hook domain-containing protein. (1312 aa)
	rad50	Zinc-hook domain-containing protein. (1311 aa)
	A0A1L8GS29	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (268 aa)
	Rad26	Uncharacterized protein. (798 aa)
	atrip	Uncharacterized protein. (801 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	Exo1.S	Uncharacterized protein. (734 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	Dna2.S	Uncharacterized protein. (1053 aa)
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	atad5	AAA domain-containing protein. (1740 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GS29	Chek2.L	A0A1L8GS29	A0A1L8I0A0	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.491
A0A1L8GS29	Dna2.S	A0A1L8GS29	A0A1L8FF41	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.794
A0A1L8GS29	Exo1.S	A0A1L8GS29	A0A1L8F3G5	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.977
A0A1L8GS29	Rfc2.L	A0A1L8GS29	A0A1L8HGA4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	AAA domain-containing protein.	0.996
A0A1L8GS29	Xpa.L	A0A1L8GS29	A0A1L8HX71	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	XPA_C domain-containing protein.	0.702
A0A1L8GS29	atad5	A0A1L8GS29	A0A1L8EV17	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	AAA domain-containing protein.	0.968
A0A1L8GS29	chek1	A0A1L8GS29	A0A1L8FFS1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.635
A0A1L8GS29	chek1-2	A0A1L8GS29	A0A1L8FL95	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Protein kinase domain-containing protein.	0.635
A0A1L8GS29	rad50	A0A1L8GS29	A0A1L8GVF0	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Zinc-hook domain-containing protein.	0.481
A0A1L8GS29	rad50-2	A0A1L8GS29	A0A1L8GXM0	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Zinc-hook domain-containing protein.	0.481
A0A1L8GS29	rfc3	A0A1L8GS29	Q4QQP4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	MGC115007 protein.	0.998
A0A1L8GS29	rfc4	A0A1L8GS29	Q76LD2	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Replication factor C p37 subunit.	0.999
A0A1L8GS29	rfc5	A0A1L8GS29	Q7ZTM5	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Rfc5-prov protein.	0.981
Chek2.L	A0A1L8GS29	A0A1L8I0A0	A0A1L8GS29	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.491
Chek2.L	Clspn.S	A0A1L8I0A0	F8WKR8	Uncharacterized protein.	Claspin.	0.891
Chek2.L	Dna2.S	A0A1L8I0A0	A0A1L8FF41	Uncharacterized protein.	Uncharacterized protein.	0.910
Chek2.L	Exo1.S	A0A1L8I0A0	A0A1L8F3G5	Uncharacterized protein.	Uncharacterized protein.	0.974
Chek2.L	Hus1	A0A1L8I0A0	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.948
Chek2.L	Rad26	A0A1L8I0A0	A0A1L8GP12	Uncharacterized protein.	Uncharacterized protein.	0.895
Chek2.L	Rfc2.L	A0A1L8I0A0	A0A1L8HGA4	Uncharacterized protein.	AAA domain-containing protein.	0.641