41 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	A0A1L8F564	Mothers against decapentaplegic homolog. (564 aa)
	A0A1L8F5B3	Mothers against decapentaplegic homolog. (338 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	A0A1L8FDB0	Mothers against decapentaplegic homolog. (514 aa)
	A0A1L8FDC7	Mothers against decapentaplegic homolog. (371 aa)
	Sfrp5.S	Uncharacterized protein. (315 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	sfrp4	Uncharacterized protein. (353 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	tgfb2-2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	ryk	Uncharacterized protein. (596 aa)
	Dkk3.S	Dickkopf_N domain-containing protein. (257 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	sfrp1	Uncharacterized protein. (311 aa)
	Smad3	Mothers against decapentaplegic homolog. (425 aa)
	wif1	Uncharacterized protein. (374 aa)
	Sfrp1.L	Uncharacterized protein. (311 aa)
	Smad9.S	Mothers against decapentaplegic homolog. (465 aa)
	Smad8c	Mothers against decapentaplegic homolog. (466 aa)
	A0A1L8HLT3	Mothers against decapentaplegic homolog. (380 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	dkk2	Dickkopf_N domain-containing protein. (255 aa)
	ror2	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	A0A1L8HRY9	Mothers against decapentaplegic homolog. (549 aa)
	smad7	Mothers against decapentaplegic homolog. (382 aa)
	A0A1L8HS33	Mothers against decapentaplegic homolog. (427 aa)
	A0A1L8HUK7	Mothers against decapentaplegic homolog. (422 aa)
	A0A1L8I2V3	Mothers against decapentaplegic homolog. (510 aa)
	Mad2	Mothers against decapentaplegic homolog. (467 aa)
	smad6	Mothers against decapentaplegic homolog. (352 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	smad7-2	Mothers against decapentaplegic homolog. (382 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	smad6-2	Mothers against decapentaplegic homolog. (354 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	ror2-2	Receptor tyrosine kinase Xror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (930 aa)
	sfrp5	Secreted frizzled-related protein 5. (315 aa)
	smad3	Mothers against decapentaplegic homolog. (425 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	dkk2-2	Dickkopf homolog 2. (255 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8F564	A0A1L8HRY9	A0A1L8F564	A0A1L8HRY9	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.902
A0A1L8F564	Mad2	A0A1L8F564	A0A1L8I2V8	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.900
A0A1L8F564	Smad3	A0A1L8F564	A0A1L8GSA7	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.900
A0A1L8F564	Smad8c	A0A1L8F564	A0A1L8HIU3	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.900
A0A1L8F564	Smad9.S	A0A1L8F564	A0A1L8HAF8	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.900
A0A1L8F564	lef1	A0A1L8F564	A0A1L8HM07	Mothers against decapentaplegic homolog.	HMG box domain-containing protein.	0.915
A0A1L8F564	lef1-2	A0A1L8F564	Q90ZB8	Mothers against decapentaplegic homolog.	Lymphoid enhancer factor XLEF-1.	0.915
A0A1L8F564	smad3	A0A1L8F564	Q90YE5	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.900
A0A1L8F5B3	A0A1L8FDB0	A0A1L8F5B3	A0A1L8FDB0	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.474
A0A1L8F5B3	A0A1L8HRY9	A0A1L8F5B3	A0A1L8HRY9	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.474
A0A1L8F5B3	A0A1L8I2V3	A0A1L8F5B3	A0A1L8I2V3	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.474
A0A1L8F5B3	tgfb1	A0A1L8F5B3	A0A1L8F3Y7	Mothers against decapentaplegic homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.616
A0A1L8F5B3	tgfb1-2	A0A1L8F5B3	A0A1L8F936	Mothers against decapentaplegic homolog.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.616
A0A1L8FDB0	A0A1L8F5B3	A0A1L8FDB0	A0A1L8F5B3	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.474
A0A1L8FDB0	A0A1L8FDC7	A0A1L8FDB0	A0A1L8FDC7	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.474
A0A1L8FDB0	A0A1L8HLT3	A0A1L8FDB0	A0A1L8HLT3	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.769
A0A1L8FDB0	A0A1L8HS33	A0A1L8FDB0	A0A1L8HS33	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.877
A0A1L8FDB0	A0A1L8HUK7	A0A1L8FDB0	A0A1L8HUK7	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.965
A0A1L8FDB0	Mad2	A0A1L8FDB0	A0A1L8I2V8	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.877
A0A1L8FDB0	Smad3	A0A1L8FDB0	A0A1L8GSA7	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.877