31 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	stmn2	Stathmin; Belongs to the stathmin family. (178 aa)
	stmn3-2	Stathmin; Belongs to the stathmin family. (180 aa)
	stmn2-2	Stathmin; Belongs to the stathmin family. (178 aa)
	stmn3	Stathmin; Belongs to the stathmin family. (180 aa)
	ins-2	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	pik3c3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (886 aa)
	Egf.L	Uncharacterized protein. (1031 aa)
	stmn1	Stathmin; Belongs to the stathmin family. (145 aa)
	epn3	ENTH domain-containing protein. (601 aa)
	grb2	Uncharacterized protein. (229 aa)
	erbb2	Receptor protein-tyrosine kinase. (1299 aa)
	epn3-2	ENTH domain-containing protein. (601 aa)
	grb2-2	Uncharacterized protein. (229 aa)
	A0A1L8EYG2	ENTH domain-containing protein. (588 aa)
	tgfb1	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	tgfb1-2	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	Epn2.S	ENTH domain-containing protein. (594 aa)
	A0A1L8FND1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
	egfr	Receptor protein-tyrosine kinase. (1208 aa)
	tfap2a	TF_AP-2 domain-containing protein. (470 aa)
	egfr-2	Receptor protein-tyrosine kinase. (1210 aa)
	Tfap2a.L	TF_AP-2 domain-containing protein. (472 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	pik3cb	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	stmn4	Stathmin; Belongs to the stathmin family. (185 aa)
	tgfb2-2	Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
	pik3cb-2	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	pik3cg	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
	Slc2a4.L	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	Stmn1.S	Uncharacterized protein. (242 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8EYG2	Egf.L	A0A1L8EYG2	A0A1L8HUT3	ENTH domain-containing protein.	Uncharacterized protein.	0.566
A0A1L8EYG2	Tfap2a.L	A0A1L8EYG2	A0A1L8FXY3	ENTH domain-containing protein.	TF_AP-2 domain-containing protein.	0.742
A0A1L8EYG2	egfr	A0A1L8EYG2	A0A1L8FRS8	ENTH domain-containing protein.	Receptor protein-tyrosine kinase.	0.829
A0A1L8EYG2	egfr-2	A0A1L8EYG2	A0A1L8FWP8	ENTH domain-containing protein.	Receptor protein-tyrosine kinase.	0.829
A0A1L8EYG2	erbb2	A0A1L8EYG2	A0A1L8ES20	ENTH domain-containing protein.	Receptor protein-tyrosine kinase.	0.484
A0A1L8EYG2	grb2	A0A1L8EYG2	A0A1L8EMZ6	ENTH domain-containing protein.	Uncharacterized protein.	0.637
A0A1L8EYG2	grb2-2	A0A1L8EYG2	A0A1L8EUF2	ENTH domain-containing protein.	Uncharacterized protein.	0.637
A0A1L8EYG2	tfap2a	A0A1L8EYG2	A0A1L8FS35	ENTH domain-containing protein.	TF_AP-2 domain-containing protein.	0.741
A0A1L8FND1	Egf.L	A0A1L8FND1	A0A1L8HUT3	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.962
A0A1L8FND1	Slc2a4.L	A0A1L8FND1	A0A1L8H4N2	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.924
A0A1L8FND1	egfr	A0A1L8FND1	A0A1L8FRS8	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Receptor protein-tyrosine kinase.	0.876
A0A1L8FND1	egfr-2	A0A1L8FND1	A0A1L8FWP8	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Receptor protein-tyrosine kinase.	0.876
A0A1L8FND1	erbb2	A0A1L8FND1	A0A1L8ES20	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Receptor protein-tyrosine kinase.	0.795
A0A1L8FND1	grb2	A0A1L8FND1	A0A1L8EMZ6	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.722
A0A1L8FND1	grb2-2	A0A1L8FND1	A0A1L8EUF2	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.722
A0A1L8FND1	ins	A0A1L8FND1	A0A1L8GD41	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.907
A0A1L8FND1	ins-2	A0A1L8FND1	B7ZQP1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.905
A0A1L8FND1	tgfb1	A0A1L8FND1	A0A1L8F3Y7	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.683
A0A1L8FND1	tgfb1-2	A0A1L8FND1	A0A1L8F936	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.683
Egf.L	A0A1L8EYG2	A0A1L8HUT3	A0A1L8EYG2	Uncharacterized protein.	ENTH domain-containing protein.	0.566