21 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gap43	Uncharacterized protein. (214 aa)
	pard6b-2	Uncharacterized protein. (376 aa)
	ntn1-2	Uncharacterized protein. (602 aa)
	Smurf1.L	E3 ubiquitin-protein ligase. (731 aa)
	ntn3-2	Uncharacterized protein. (588 aa)
	ntn5	Uncharacterized protein. (601 aa)
	A0A1L8FQM4	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	h1f0	H15 domain-containing protein. (196 aa)
	h1f0-2	H15 domain-containing protein. (194 aa)
	ntn3	Uncharacterized protein. (588 aa)
	Gap43.L	Uncharacterized protein. (212 aa)
	Alb.S	Uncharacterized protein. (607 aa)
	ntn5-2	LOC100127305 protein. (601 aa)
	LOC100189571	Uncharacterized protein. (608 aa)
	rac1	MGC114731 protein. (192 aa)
	rhoa	MGC64296 protein. (193 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	pard6b	Uncharacterized protein. (377 aa)
	ntn1	Uncharacterized protein. (602 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FQM4	actl6a	A0A1L8FQM4	Q7ZYI5	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Baf53a-pending-prov protein; Belongs to the actin family.	0.489
A0A1L8FQM4	ntn1	A0A1L8FQM4	A0A1L8EN54	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.521
A0A1L8FQM4	ntn1-2	A0A1L8FQM4	A0A1L8EV13	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.488
A0A1L8FQM4	ntn3	A0A1L8FQM4	A0A1L8EQL7	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.485
A0A1L8FQM4	ntn3-2	A0A1L8FQM4	A0A1L8EY77	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.485
A0A1L8FQM4	ntn5	A0A1L8FQM4	A0A1L8FGS1	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Uncharacterized protein.	0.485
A0A1L8FQM4	ntn5-2	A0A1L8FQM4	A9JS48	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	LOC100127305 protein.	0.485
Alb.S	Shh.L	A0A1L8HMG9	A0A1L8FV87	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.429
Alb.S	actl6a	A0A1L8HMG9	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.882
Gap43.L	actl6a	A0A1L8HC99	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.445
Gap43.L	ntn3	A0A1L8HC99	A0A1L8EQL7	Uncharacterized protein.	Uncharacterized protein.	0.400
Gap43.L	ntn3-2	A0A1L8HC99	A0A1L8EY77	Uncharacterized protein.	Uncharacterized protein.	0.400
Gap43.L	ntn5	A0A1L8HC99	A0A1L8FGS1	Uncharacterized protein.	Uncharacterized protein.	0.400
Gap43.L	ntn5-2	A0A1L8HC99	A9JS48	Uncharacterized protein.	LOC100127305 protein.	0.400
Gap43.L	rhoa	A0A1L8HC99	Q7SZA9	Uncharacterized protein.	MGC64296 protein.	0.404
LOC100189571	Shh.L	B7ZRX0	A0A1L8FV87	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.482
LOC100189571	actl6a	B7ZRX0	Q7ZYI5	Uncharacterized protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.883
LOC100189571	rhoa	B7ZRX0	Q7SZA9	Uncharacterized protein.	MGC64296 protein.	0.431
Prkci.L	Smurf1.L	A0A1L8GAK2	A0A1L8EX82	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	E3 ubiquitin-protein ligase.	0.743
Prkci.L	actl6a	A0A1L8GAK2	Q7ZYI5	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	Baf53a-pending-prov protein; Belongs to the actin family.	0.768