54 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ctnnb1	Beta-catenin protein. (781 aa)
	emx2-2	MGC81839 protein. (245 aa)
	sfrp2-2	Sfrp2-prov protein. (298 aa)
	gbx2.1-2	Homeobox protein GBX-2b. (336 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	ptch1-2	Patched-1. (1418 aa)
	csrnp1	CSRNP_N domain-containing protein. (570 aa)
	A0A1L8FQM4	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (429 aa)
	gli3	Uncharacterized protein. (1565 aa)
	Wnt9a.S	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (528 aa)
	Csrnp1.L	CSRNP_N domain-containing protein. (568 aa)
	Shh.L	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (444 aa)
	gli3-2	Uncharacterized protein. (1568 aa)
	apcdd1	Uncharacterized protein. (515 aa)
	Chrd.1.S	Chordin; Belongs to the chordin family. (941 aa)
	nkx2-2-2	Homeobox domain-containing protein. (271 aa)
	A0A1L8GA23	Chordin; Belongs to the chordin family. (940 aa)
	A0A1L8GA54	Uncharacterized protein. (882 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	sfrp1	Uncharacterized protein. (311 aa)
	ctbp2l	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (480 aa)
	Sfrp1.L	Uncharacterized protein. (311 aa)
	bmp1	Metalloendopeptidase. (976 aa)
	A0A1L8H5Q6	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (420 aa)
	nck2	Cytoplasmic protein. (381 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	Fzd4.S	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (523 aa)
	nck2-2	Cytoplasmic protein. (381 aa)
	Wnt1.L	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	ctbp1	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (441 aa)
	sfrp2	Uncharacterized protein. (295 aa)
	gbx2.1	Homeobox domain-containing protein. (340 aa)
	wnt6-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	Xwnt-8b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (428 aa)
	Bmp1	Metalloendopeptidase. (977 aa)
	wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	nck1	Cytoplasmic protein. (377 aa)
	nck1-2	Cytoplasmic protein. (377 aa)
	axin2-2	MGC81576 protein. (707 aa)
	fzd2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	A0A1L8ENI4	Uncharacterized protein. (815 aa)
	gbx2.2	Homeobox domain-containing protein. (340 aa)
	A0A1L8EUY4	Uncharacterized protein. (818 aa)
	wnt6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	Gbx2.2.L	Homeobox domain-containing protein. (340 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	emx2	Homeobox domain-containing protein. (243 aa)
	ctbp2	Uncharacterized protein. (973 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	wnt4-2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	axin2	Uncharacterized protein. (707 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ENI4	A0A1L8H5Q6	A0A1L8ENI4	A0A1L8H5Q6	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.998
A0A1L8ENI4	Fzd4.S	A0A1L8ENI4	A0A1L8HB90	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.665
A0A1L8ENI4	Lrp5.L	A0A1L8ENI4	A0A1L8GJX4	Uncharacterized protein.	Uncharacterized protein.	0.928
A0A1L8ENI4	Sfrp1.L	A0A1L8ENI4	A0A1L8H1S5	Uncharacterized protein.	Uncharacterized protein.	0.753
A0A1L8ENI4	Shh.L	A0A1L8ENI4	A0A1L8FV87	Uncharacterized protein.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.668
A0A1L8ENI4	Wnt1.L	A0A1L8ENI4	A0A1L8HHR8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.872
A0A1L8ENI4	Wnt9a.S	A0A1L8ENI4	A0A1L8FUX2	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.571
A0A1L8ENI4	Xwnt-8b	A0A1L8ENI4	B7ZQM6	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.719
A0A1L8ENI4	ctnnb1	A0A1L8ENI4	Q63ZT4	Uncharacterized protein.	Beta-catenin protein.	0.998
A0A1L8ENI4	fzd2	A0A1L8ENI4	A0A1L8EL29	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.694
A0A1L8ENI4	fzd7	A0A1L8ENI4	A0A1L8EX17	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.652
A0A1L8ENI4	lef1	A0A1L8ENI4	A0A1L8HM07	Uncharacterized protein.	HMG box domain-containing protein.	0.922
A0A1L8ENI4	lef1-2	A0A1L8ENI4	Q90ZB8	Uncharacterized protein.	Lymphoid enhancer factor XLEF-1.	0.922
A0A1L8ENI4	ptch1-2	A0A1L8ENI4	Q98SW6	Uncharacterized protein.	Patched-1.	0.523
A0A1L8ENI4	sfrp1	A0A1L8ENI4	A0A1L8GRT5	Uncharacterized protein.	Uncharacterized protein.	0.720
A0A1L8ENI4	sfrp2	A0A1L8ENI4	A0A1L8HUI3	Uncharacterized protein.	Uncharacterized protein.	0.667
A0A1L8ENI4	sfrp2-2	A0A1L8ENI4	Q7ZXM6	Uncharacterized protein.	Sfrp2-prov protein.	0.667
A0A1L8ENI4	wnt1	A0A1L8ENI4	A0A1L8H9S8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.872
A0A1L8ENI4	wnt11	A0A1L8ENI4	A0A1L8HJX1	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.668
A0A1L8ENI4	wnt11b	A0A1L8ENI4	A0A1L8F6W4	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.667