18 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pard6b	Uncharacterized protein. (377 aa)
	cldn1-2	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	actl6a	Baf53a-pending-prov protein; Belongs to the actin family. (429 aa)
	cdx2-2	Homeobox domain-containing protein. (254 aa)
	cdx2	MGC130987 protein. (256 aa)
	cdh11-2	Cadherin; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
	Tjp1.S	Uncharacterized protein; Belongs to the MAGUK family. (1705 aa)
	cdh3	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (905 aa)
	cdh1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (871 aa)
	Cdh3.S	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (880 aa)
	pxdn-2	Uncharacterized protein. (1464 aa)
	Prkci.L	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	cldn1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	pxdn	Uncharacterized protein. (1461 aa)
	pou5f3.2	POU domain protein. (449 aa)
	Pou5f3.1	POU domain protein. (445 aa)
	Lrp2.L	Uncharacterized protein. (4658 aa)
	pard6b-2	Uncharacterized protein. (376 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdh3.S	Pou5f3.1	A0A1L8GET9	A0A1L8F5T5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	POU domain protein.	0.618
Cdh3.S	Prkci.L	A0A1L8GET9	A0A1L8GAK2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.694
Cdh3.S	Tjp1.S	A0A1L8GET9	A0A1L8H090	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Belongs to the MAGUK family.	0.949
Cdh3.S	actl6a	A0A1L8GET9	Q7ZYI5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Baf53a-pending-prov protein; Belongs to the actin family.	0.931
Cdh3.S	cdh1	A0A1L8GET9	A0A1L8GKV4	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.903
Cdh3.S	cdh11-2	A0A1L8GET9	O93264	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin; Cadherins are calcium-dependent cell adhesion proteins.	0.536
Cdh3.S	cdh3	A0A1L8GET9	A0A1L8GKW6	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.901
Cdh3.S	cldn1	A0A1L8GET9	A0A1L8GA96	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.745
Cdh3.S	cldn1-2	A0A1L8GET9	Q8AVG4	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.745
Cdh3.S	pard6b	A0A1L8GET9	A0A1L8ELH2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.573
Cdh3.S	pard6b-2	A0A1L8GET9	A0A1L8ESP6	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.573
Cdh3.S	pou5f3.2	A0A1L8GET9	A0A1L8F5T8	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	POU domain protein.	0.610
Cdh3.S	pxdn	A0A1L8GET9	A0A1L8G530	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.592
Cdh3.S	pxdn-2	A0A1L8GET9	A0A1L8GBD8	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein.	0.592
Pou5f3.1	Cdh3.S	A0A1L8F5T5	A0A1L8GET9	POU domain protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.618
Pou5f3.1	actl6a	A0A1L8F5T5	Q7ZYI5	POU domain protein.	Baf53a-pending-prov protein; Belongs to the actin family.	0.599
Pou5f3.1	cdh1	A0A1L8F5T5	A0A1L8GKV4	POU domain protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.607
Pou5f3.1	cdh3	A0A1L8F5T5	A0A1L8GKW6	POU domain protein.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.614
Pou5f3.1	cdx2	A0A1L8F5T5	Q2T9K7	POU domain protein.	MGC130987 protein.	0.812
Pou5f3.1	cdx2-2	A0A1L8F5T5	Q32NJ4	POU domain protein.	Homeobox domain-containing protein.	0.808