12 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Exo1.S	Uncharacterized protein. (734 aa)
	Brca1.L	Uncharacterized protein. (1582 aa)
	recql5	Uncharacterized protein. (1090 aa)
	crb2	Uncharacterized protein. (1472 aa)
	Dna2.S	Uncharacterized protein. (1053 aa)
	Atr.L	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2654 aa)
	rad50	Zinc-hook domain-containing protein. (1311 aa)
	rad50-2	Zinc-hook domain-containing protein. (1312 aa)
	Chek2.L	Uncharacterized protein. (392 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atr.L	Brca1.L	A0A1L8GAP7	A0A1L8ETS4	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.998
Atr.L	Chek2.L	A0A1L8GAP7	A0A1L8I0A0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.999
Atr.L	Dna2.S	A0A1L8GAP7	A0A1L8FF41	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.982
Atr.L	Exo1.S	A0A1L8GAP7	A0A1L8F3G5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.995
Atr.L	Hus1	A0A1L8GAP7	Q8JHD8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Checkpoint protein; Belongs to the HUS1 family.	0.999
Atr.L	crb2	A0A1L8GAP7	A0A1L8F1Z8	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.478
Atr.L	pcna	A0A1L8GAP7	Q9I893	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.743
Atr.L	rad50	A0A1L8GAP7	A0A1L8GVF0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Zinc-hook domain-containing protein.	0.955
Atr.L	rad50-2	A0A1L8GAP7	A0A1L8GXM0	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Zinc-hook domain-containing protein.	0.955
Atr.L	rad9a	A0A1L8GAP7	Q7ZZU5	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.998
Atr.L	recql5	A0A1L8GAP7	A0A1L8EUG1	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.957
Brca1.L	Atr.L	A0A1L8ETS4	A0A1L8GAP7	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.998
Brca1.L	Chek2.L	A0A1L8ETS4	A0A1L8I0A0	Uncharacterized protein.	Uncharacterized protein.	0.992
Brca1.L	Dna2.S	A0A1L8ETS4	A0A1L8FF41	Uncharacterized protein.	Uncharacterized protein.	0.969
Brca1.L	Exo1.S	A0A1L8ETS4	A0A1L8F3G5	Uncharacterized protein.	Uncharacterized protein.	0.986
Brca1.L	Hus1	A0A1L8ETS4	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.885
Brca1.L	pcna	A0A1L8ETS4	Q9I893	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.528
Brca1.L	rad50	A0A1L8ETS4	A0A1L8GVF0	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.963
Brca1.L	rad50-2	A0A1L8ETS4	A0A1L8GXM0	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.963
Brca1.L	rad9a	A0A1L8ETS4	Q7ZZU5	Uncharacterized protein.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.905