STRINGSTRING
Zeb1.S Zeb1.S ncoa3 ncoa3 erbb2 erbb2 Smurf1.L Smurf1.L A0A1L8EYQ3 A0A1L8EYQ3 prickle3-b prickle3-b tgfb1 tgfb1 tgfb1-2 tgfb1-2 prkcz prkcz Rel.L Rel.L Prkci.L Prkci.L rela rela prickle2 prickle2 rela-2 rela-2 prickle2-2 prickle2-2 prickle1 prickle1 Prickle1.L Prickle1.L ikbkb ikbkb stk11 stk11 mapk1 mapk1 stk11-2 stk11-2 Mapk1.L Mapk1.L rac1 rac1 ctnnb1 ctnnb1 myc myc rhoa rhoa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Zeb1.SUncharacterized protein. (919 aa)
ncoa3Nuclear receptor coactivator. (1391 aa)
erbb2Receptor protein-tyrosine kinase. (1299 aa)
Smurf1.LE3 ubiquitin-protein ligase. (731 aa)
A0A1L8EYQ3LLGL domain-containing protein. (1049 aa)
prickle3-bPrickle planar cell polarity protein 3-B; Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (By similarity). PCP is maintained by two molecular modules, the global and the core modules. Proteins of the core module include the proteins Frizzled (Fz), Disheveled (Dsh), Van Gogh (Vang), Prickle (Pk), Flamingo (Fmi, Celsr) and Diego (Dgo). The core module proteins develop subcellular asymmetry, accumulating in two groups on opposite sides of epithelial cells. D [...] (536 aa)
tgfb1Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
tgfb1-2Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
prkczProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (590 aa)
Rel.LRHD domain-containing protein. (583 aa)
Prkci.LProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
relaRHD_dimer domain-containing protein. (309 aa)
prickle2Uncharacterized protein. (833 aa)
rela-2RHD domain-containing protein. (527 aa)
prickle2-2Uncharacterized protein. (833 aa)
prickle1Uncharacterized protein. (835 aa)
Prickle1.LUncharacterized protein. (832 aa)
ikbkbUncharacterized protein. (769 aa)
stk11Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
stk11-2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
Mapk1.LMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
rac1MGC114731 protein. (192 aa)
ctnnb1Beta-catenin protein. (781 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
rhoaMGC64296 protein. (193 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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