17 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Orc2.S	Uncharacterized protein. (558 aa)
	Brca1.L	Uncharacterized protein. (1582 aa)
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	chek1-2	Protein kinase domain-containing protein. (510 aa)
	topbp1	Uncharacterized protein. (1573 aa)
	atrip	Uncharacterized protein. (801 aa)
	mcm2	DNA helicase; Belongs to the MCM family. (885 aa)
	Rad26	Uncharacterized protein. (798 aa)
	Mcm2.L	DNA helicase; Belongs to the MCM family. (886 aa)
	A0A1L8GS29	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (268 aa)
	Rfc2.L	AAA domain-containing protein. (359 aa)
	Rad17.L	Uncharacterized protein. (674 aa)
	chaf1b	Chromatin assembly factor 1. (569 aa)
	rfc4	Replication factor C p37 subunit. (363 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (377 aa)
	Hus1	Checkpoint protein; Belongs to the HUS1 family. (282 aa)
	pcna	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8GS29	Brca1.L	A0A1L8GS29	A0A1L8ETS4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.480
A0A1L8GS29	Mcm2.L	A0A1L8GS29	A0A1L8GPN4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA helicase; Belongs to the MCM family.	0.864
A0A1L8GS29	Orc2.S	A0A1L8GS29	A0A1L8EPN0	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.620
A0A1L8GS29	Rad17.L	A0A1L8GS29	A0A1L8I1Y0	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.904
A0A1L8GS29	Rfc2.L	A0A1L8GS29	A0A1L8HGA4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	AAA domain-containing protein.	0.996
A0A1L8GS29	chaf1b	A0A1L8GS29	A0PCL5	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Chromatin assembly factor 1.	0.950
A0A1L8GS29	chek1	A0A1L8GS29	A0A1L8FFS1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.635
A0A1L8GS29	chek1-2	A0A1L8GS29	A0A1L8FL95	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Protein kinase domain-containing protein.	0.635
A0A1L8GS29	mcm2	A0A1L8GS29	A0A1L8GHP1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA helicase; Belongs to the MCM family.	0.864
A0A1L8GS29	rfc4	A0A1L8GS29	Q76LD2	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Replication factor C p37 subunit.	0.999
Brca1.L	A0A1L8GS29	A0A1L8ETS4	A0A1L8GS29	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.480
Brca1.L	Hus1	A0A1L8ETS4	Q8JHD8	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.885
Brca1.L	Rad17.L	A0A1L8ETS4	A0A1L8I1Y0	Uncharacterized protein.	Uncharacterized protein.	0.877
Brca1.L	Rad26	A0A1L8ETS4	A0A1L8GP12	Uncharacterized protein.	Uncharacterized protein.	0.959
Brca1.L	Rfc2.L	A0A1L8ETS4	A0A1L8HGA4	Uncharacterized protein.	AAA domain-containing protein.	0.881
Brca1.L	atrip	A0A1L8ETS4	A0A1L8GH95	Uncharacterized protein.	Uncharacterized protein.	0.959
Brca1.L	chek1	A0A1L8ETS4	A0A1L8FFS1	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.980
Brca1.L	chek1-2	A0A1L8ETS4	A0A1L8FL95	Uncharacterized protein.	Protein kinase domain-containing protein.	0.980
Brca1.L	mcm2	A0A1L8ETS4	A0A1L8GHP1	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.430
Brca1.L	pcna	A0A1L8ETS4	Q9I893	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.528