22 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Rangap1.S	RanGAP1_C domain-containing protein. (583 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	rangap1	Rangap1-prov protein. (584 aa)
	uchl3-2	Ubiquitin carboxyl-terminal hydrolase. (230 aa)
	senp8-2	MGC84956 protein. (214 aa)
	senp7	Sentrin/SUMO-specific protease 7. (901 aa)
	senp5-2	Sentrin/SUMO-specific protease 5. (722 aa)
	pkd2	EF-hand domain-containing protein. (947 aa)
	A0A1L8HPJ8	Ubiquitin-like domain-containing protein. (125 aa)
	Senp1.L	ULP_PROTEASE domain-containing protein. (616 aa)
	ranbp2	Uncharacterized protein. (2905 aa)
	Senp1.S	ULP_PROTEASE domain-containing protein. (546 aa)
	uchl3	Ubiquitin carboxyl-terminal hydrolase. (230 aa)
	senp8	ULP_PROTEASE domain-containing protein. (214 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	uba2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (641 aa)
	senp5	ULP_PROTEASE domain-containing protein. (710 aa)
	sae1	ThiF domain-containing protein. (344 aa)
	Sumo1.L	Ubiquitin-like domain-containing protein. (148 aa)
	Sumo1.S	Ubiquitin-like domain-containing protein. (141 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	Senp6.S	ULP_PROTEASE domain-containing protein. (1103 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8HPJ8	Senp1.L	A0A1L8HPJ8	A0A1L8HIA0	Ubiquitin-like domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.584
A0A1L8HPJ8	Senp1.S	A0A1L8HPJ8	A0A1L8H9Y3	Ubiquitin-like domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.584
A0A1L8HPJ8	Sumo1.L	A0A1L8HPJ8	A0A1L8EWZ5	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.924
A0A1L8HPJ8	Sumo1.S	A0A1L8HPJ8	A0A1L8EPQ0	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.924
A0A1L8HPJ8	sae1	A0A1L8HPJ8	A0A1L8F8T2	Ubiquitin-like domain-containing protein.	ThiF domain-containing protein.	0.787
A0A1L8HPJ8	senp5	A0A1L8HPJ8	A0A1L8G3T3	Ubiquitin-like domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.440
A0A1L8HPJ8	senp5-2	A0A1L8HPJ8	B6RQN8	Ubiquitin-like domain-containing protein.	Sentrin/SUMO-specific protease 5.	0.440
A0A1L8HPJ8	senp8	A0A1L8HPJ8	A0A1L8GTG2	Ubiquitin-like domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.994
A0A1L8HPJ8	senp8-2	A0A1L8HPJ8	Q5FWL6	Ubiquitin-like domain-containing protein.	MGC84956 protein.	0.994
A0A1L8HPJ8	sumo2	A0A1L8HPJ8	A0A1L8EMU2	Ubiquitin-like domain-containing protein.	Small ubiquitin-related modifier.	0.965
A0A1L8HPJ8	uba2	A0A1L8HPJ8	A0A1L8GLB0	Ubiquitin-like domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.814
A0A1L8HPJ8	uchl3	A0A1L8HPJ8	A0A1L8H960	Ubiquitin-like domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase.	0.814
A0A1L8HPJ8	uchl3-2	A0A1L8HPJ8	Q5XHE2	Ubiquitin-like domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase.	0.814
Jun.L	c-Jun	A0A1L8GLZ4	Q9PVZ1	BZIP domain-containing protein; Belongs to the bZIP family.	C-Jun protein; Belongs to the bZIP family.	0.958
Jun.L	sumo2	A0A1L8GLZ4	A0A1L8EMU2	BZIP domain-containing protein; Belongs to the bZIP family.	Small ubiquitin-related modifier.	0.614
Rangap1.S	Senp1.L	A0A1L8GH35	A0A1L8HIA0	RanGAP1_C domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.882
Rangap1.S	Senp1.S	A0A1L8GH35	A0A1L8H9Y3	RanGAP1_C domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.882
Rangap1.S	Senp6.S	A0A1L8GH35	A0A1L8G3E0	RanGAP1_C domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.763
Rangap1.S	Sumo1.L	A0A1L8GH35	A0A1L8EWZ5	RanGAP1_C domain-containing protein.	Ubiquitin-like domain-containing protein.	0.995
Rangap1.S	Sumo1.S	A0A1L8GH35	A0A1L8EPQ0	RanGAP1_C domain-containing protein.	Ubiquitin-like domain-containing protein.	0.995