STRINGSTRING
srf srf slc8a1 slc8a1 pln pln gja1 gja1 id2 id2 gata4 gata4 srf-2 srf-2 tbx3 tbx3 nppa nppa klf9 klf9 gapdh gapdh Gapdh.S Gapdh.S nkx2-5-2 nkx2-5-2 atp1a2 atp1a2 acta2 acta2 actn2 actn2 gata4-2 gata4-2 pitx2 pitx2 myod1-a myod1-a tbx5-2 tbx5-2 tbx3-A tbx3-A A0A310TTQ1 A0A310TTQ1 mef2c-2 mef2c-2 hopx hopx Pitx2.S Pitx2.S hand2 hand2 Kit.L Kit.L mef2c mef2c Myl2.S Myl2.S tbx5 tbx5 Kit.S Kit.S gja5-2 gja5-2 gja5 gja5 bmp10-2 bmp10-2 sema3a-2 sema3a-2 Ascl1.L Ascl1.L nkx2-5 nkx2-5 sema3a sema3a bmp10 bmp10 myl7 myl7 Myod1.L Myod1.L Id2.L Id2.L gja1-2 gja1-2 pln-2 pln-2 Smarcd3.S Smarcd3.S h3f3b h3f3b A0A1L8EY07 A0A1L8EY07 Actn1.L Actn1.L actc1 actc1 Neurog3.S Neurog3.S A0A1L8FK38 A0A1L8FK38 thy1 thy1 col1a2 col1a2 irx4 irx4 hist2h3c hist2h3c
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
srfMADS-box domain-containing protein. (449 aa)
slc8a1J domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (978 aa)
plnCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
gja1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (379 aa)
id2BHLH domain-containing protein. (135 aa)
gata4Uncharacterized protein. (392 aa)
srf-2MADS-box domain-containing protein. (448 aa)
tbx3Transcription factor Tbx3. (711 aa)
nppaAtrial natriuretic factor. (147 aa)
klf9Basic transcription element binding protein 1. (292 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
Gapdh.SGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
nkx2-5-2Nkx2.5 protein. (299 aa)
atp1a2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
acta2MGC78870 protein. (377 aa)
actn2MGC79034 protein. (894 aa)
gata4-2MGC81427 protein. (394 aa)
pitx2Homeobox protein. (323 aa)
myod1-aMyoblast determination protein 1 homolog A; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. (289 aa)
tbx5-2T-box transcription factor Tbx5. (519 aa)
tbx3-ATranscription repression factor Tbx3. (716 aa)
A0A310TTQ1Histone H3; Belongs to the histone H3 family. (136 aa)
mef2c-2MADS-box domain-containing protein. (464 aa)
hopxHomeobox domain-containing protein. (80 aa)
Pitx2.SHomeobox protein. (326 aa)
hand2BHLH domain-containing protein. (210 aa)
Kit.LMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
mef2cMADS-box domain-containing protein. (464 aa)
Myl2.SUncharacterized protein. (167 aa)
tbx5Uncharacterized protein. (519 aa)
Kit.SMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (963 aa)
gja5-2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (364 aa)
gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (360 aa)
bmp10-2TGF_BETA_2 domain-containing protein. (421 aa)
sema3a-2Uncharacterized protein; Belongs to the semaphorin family. (774 aa)
Ascl1.LBHLH domain-containing protein. (242 aa)
nkx2-5Homeobox domain-containing protein. (300 aa)
sema3aUncharacterized protein; Belongs to the semaphorin family. (771 aa)
bmp10TGF_BETA_2 domain-containing protein. (421 aa)
myl7Uncharacterized protein. (172 aa)
Myod1.LMyogenic factor. (289 aa)
Id2.LBHLH domain-containing protein. (133 aa)
gja1-2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (379 aa)
pln-2Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
Smarcd3.SSWIB domain-containing protein. (481 aa)
h3f3bHistone H3; Belongs to the histone H3 family. (136 aa)
A0A1L8EY07Histone H3; Belongs to the histone H3 family. (120 aa)
Actn1.LUncharacterized protein. (890 aa)
actc1Uncharacterized protein. (377 aa)
Neurog3.SBHLH domain-containing protein. (304 aa)
A0A1L8FK38BHLH domain-containing protein. (224 aa)
thy1Ig-like domain-containing protein. (165 aa)
col1a2Fibrillar collagen NC1 domain-containing protein. (1358 aa)
irx4Homeobox domain-containing protein. (496 aa)
hist2h3cHistone H3; Belongs to the histone H3 family. (136 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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