STRINGSTRING
MGC80982 MGC80982 cnn1 cnn1 dynll1-2 dynll1-2 mal mal pfn2 pfn2 CNN2 CNN2 dstn dstn actl6a actl6a epha4 epha4 stmn3-2 stmn3-2 bmp7.1-2 bmp7.1-2 Pfn4.S Pfn4.S stmn4 stmn4 A0A1L8G7I3 A0A1L8G7I3 spast spast marcks-2 marcks-2 pik3cb-2 pik3cb-2 cfl1 cfl1 bdnf bdnf Cttn.S Cttn.S itfg1 itfg1 cnn3 cnn3 ckap5 ckap5 Cttn.L Cttn.L Cfl1.L Cfl1.L Cnn3.L Cnn3.L A0A1L8GNQ8 A0A1L8GNQ8 eps8 eps8 hcls1 hcls1 sema3a sema3a pik3cg pik3cg pfn1 pfn1 basp1 basp1 ntn5-2 ntn5-2 Efna5.L Efna5.L map1b-2 map1b-2 Efna2.L Efna2.L map1b map1b Efna5.S Efna5.S Efna2.S Efna2.S A0A1L8HJ91 A0A1L8HJ91 A0A1L8HEJ3 A0A1L8HEJ3 stmn1 stmn1 Ngf.L Ngf.L Robo2.S Robo2.S rdx rdx dynll2 dynll2 gsn-2 gsn-2 bdnf-2 bdnf-2 ctnnb1 ctnnb1 basp1-2 basp1-2 dnal4 dnal4 rhou rhou stmn2-2 stmn2-2 dynll1 dynll1 Stmn1.S Stmn1.S ngf ngf Bmp7.2.L Bmp7.2.L stmn3 stmn3 hcls1-2 hcls1-2 sema3a-2 sema3a-2 rac1 rac1 Wasl.L Wasl.L Eps8.L Eps8.L wasl wasl bmp7.1 bmp7.1 ntn1 ntn1 Map2.S Map2.S ntn3 ntn3 ntn1-2 ntn1-2 Map2.L Map2.L ntn3-2 ntn3-2 Cfl2.S Cfl2.S abl1 abl1 l1cam l1cam A0A1L8F270 A0A1L8F270 Was.S Was.S efna1 efna1 A0A1L8F599 A0A1L8F599 Was.L Was.L gsn gsn cfl2 cfl2 fmn1 fmn1 efna3 efna3 ntn5 ntn5 A0A1L8FR37 A0A1L8FR37 cdh2 cdh2 wnt3a wnt3a nrp1 nrp1 A0A1L8FVW9 A0A1L8FVW9 Scin.L Scin.L stmn2 stmn2 SPAST SPAST marcks marcks A0A1L8G4B9 A0A1L8G4B9 Epha4.L Epha4.L pik3cb pik3cb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MGC80982Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (295 aa)
cnn1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (297 aa)
dynll1-2Dynein light chain. (89 aa)
malMGC68692 protein. (159 aa)
pfn2Profilin; Belongs to the profilin family. (140 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (294 aa)
dstnMGC53245 protein; Belongs to the actin-binding proteins ADF family. (153 aa)
actl6aBaf53a-pending-prov protein; Belongs to the actin family. (429 aa)
epha4Pag protein. (986 aa)
stmn3-2Stathmin; Belongs to the stathmin family. (180 aa)
bmp7.1-2Osteogenic protein-1 homolog. (424 aa)
Pfn4.SProfilin; Belongs to the profilin family. (172 aa)
stmn4Stathmin; Belongs to the stathmin family. (185 aa)
A0A1L8G7I3ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (153 aa)
spastSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (595 aa)
marcks-2Uncharacterized protein. (286 aa)
pik3cb-2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
cfl1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (168 aa)
bdnfBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
Cttn.SSH3 domain-containing protein. (503 aa)
itfg1Uncharacterized protein. (601 aa)
cnn3Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (331 aa)
ckap5Uncharacterized protein. (2065 aa)
Cttn.LSH3 domain-containing protein. (551 aa)
Cfl1.LADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (292 aa)
Cnn3.LCalponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (331 aa)
A0A1L8GNQ8Dynein light chain. (163 aa)
eps8SH3 domain-containing protein. (789 aa)
hcls1SH3 domain-containing protein. (553 aa)
sema3aUncharacterized protein; Belongs to the semaphorin family. (771 aa)
pik3cgUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1115 aa)
pfn1Profilin; Belongs to the profilin family. (138 aa)
basp1MGC132184 protein. (236 aa)
ntn5-2LOC100127305 protein. (601 aa)
Efna5.LEphrin RBD domain-containing protein; Belongs to the ephrin family. (185 aa)
map1b-2Uncharacterized protein. (2255 aa)
Efna2.LEphrin RBD domain-containing protein; Belongs to the ephrin family. (198 aa)
map1bUncharacterized protein. (2247 aa)
Efna5.SEphrin RBD domain-containing protein; Belongs to the ephrin family. (185 aa)
Efna2.SEphrin RBD domain-containing protein; Belongs to the ephrin family. (198 aa)
A0A1L8HJ91FERM domain-containing protein. (557 aa)
A0A1L8HEJ3Dynein light chain. (129 aa)
stmn1Stathmin; Belongs to the stathmin family. (145 aa)
Ngf.LNGF domain-containing protein; Belongs to the NGF-beta family. (232 aa)
Robo2.SUncharacterized protein. (176 aa)
rdxFERM domain-containing protein. (602 aa)
dynll2Dynein light chain. (89 aa)
gsn-2LOC397895 protein. (729 aa)
bdnf-2Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (247 aa)
ctnnb1Beta-catenin protein. (781 aa)
basp1-2MGC84072 protein. (235 aa)
dnal4Dynein light chain. (106 aa)
rhouRac-2 protein. (243 aa)
stmn2-2Stathmin; Belongs to the stathmin family. (178 aa)
dynll1Dynein light chain. (89 aa)
Stmn1.SUncharacterized protein. (242 aa)
ngfNGF domain-containing protein; Belongs to the NGF-beta family. (242 aa)
Bmp7.2.LTGF_BETA_2 domain-containing protein. (438 aa)
stmn3Stathmin; Belongs to the stathmin family. (180 aa)
hcls1-2SH3 domain-containing protein. (554 aa)
sema3a-2Uncharacterized protein; Belongs to the semaphorin family. (774 aa)
rac1MGC114731 protein. (192 aa)
Wasl.LUncharacterized protein. (509 aa)
Eps8.LSH3 domain-containing protein. (787 aa)
waslUncharacterized protein. (509 aa)
bmp7.1TGF_BETA_2 domain-containing protein. (424 aa)
ntn1Uncharacterized protein. (602 aa)
Map2.SMicrotubule-associated protein. (1811 aa)
ntn3Uncharacterized protein. (588 aa)
ntn1-2Uncharacterized protein. (602 aa)
Map2.LMicrotubule-associated protein. (1769 aa)
ntn3-2Uncharacterized protein. (588 aa)
Cfl2.SADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (310 aa)
abl1Tyrosine-protein kinase. (1122 aa)
l1camUncharacterized protein. (1251 aa)
A0A1L8F270FERM domain-containing protein. (580 aa)
Was.SUncharacterized protein. (472 aa)
efna1Ephrin RBD domain-containing protein; Belongs to the ephrin family. (216 aa)
A0A1L8F599Ephrin RBD domain-containing protein; Belongs to the ephrin family. (97 aa)
Was.LUncharacterized protein. (471 aa)
gsnUncharacterized protein. (730 aa)
cfl2ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (167 aa)
fmn1FH2 domain-containing protein. (1393 aa)
efna3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (217 aa)
ntn5Uncharacterized protein. (601 aa)
A0A1L8FR37Uncharacterized protein. (682 aa)
cdh2Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (947 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
nrp1Neuropilin; Belongs to the neuropilin family. (926 aa)
A0A1L8FVW9Uncharacterized protein. (715 aa)
Scin.LUncharacterized protein. (714 aa)
stmn2Stathmin; Belongs to the stathmin family. (178 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (600 aa)
marcksUncharacterized protein. (287 aa)
A0A1L8G4B9Profilin; Belongs to the profilin family. (126 aa)
Epha4.LUncharacterized protein. (1022 aa)
pik3cbUncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
Server load: low (24%) [HD]