77 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	vangl1-2	Vang-like protein. (499 aa)
	Tpm1.L	Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
	wif1	Uncharacterized protein. (374 aa)
	Tm7	Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
	ccnb2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (392 aa)
	Wnt5b.S	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa)
	Mmp2.S	Uncharacterized protein. (656 aa)
	Dkk3.S	Dickkopf_N domain-containing protein. (257 aa)
	ins	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	pxdn-2	Uncharacterized protein. (1464 aa)
	Tbx18.L	Uncharacterized protein. (576 aa)
	tcf21	BHLH domain-containing protein. (179 aa)
	rab3gap2	Uncharacterized protein. (1390 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (932 aa)
	Bmp2.L	TGF_BETA_2 domain-containing protein. (398 aa)
	gata4	Uncharacterized protein. (392 aa)
	pxdn	Uncharacterized protein. (1461 aa)
	tbx18	Uncharacterized protein. (558 aa)
	bmp2	TGF_BETA_2 domain-containing protein. (398 aa)
	Wisp1.L	Uncharacterized protein. (362 aa)
	col1a2	Fibrillar collagen NC1 domain-containing protein. (1358 aa)
	fzd1	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Tgfbr1.S	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (454 aa)
	axin2	Uncharacterized protein. (707 aa)
	A0A1L8FND1	IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
	wnt11b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	Exo1.S	Uncharacterized protein. (734 aa)
	fzd7	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	ndufb3-2	Uncharacterized protein. (97 aa)
	Col6a2.L	Uncharacterized protein. (1014 aa)
	Frzb-1	Uncharacterized protein. (319 aa)
	A0A1L8EUY4	Uncharacterized protein. (818 aa)
	aurka	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (407 aa)
	ndufb3	Uncharacterized protein. (97 aa)
	col6a2	Uncharacterized protein. (1014 aa)
	fzd2	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (551 aa)
	A0A1L8ENI4	Uncharacterized protein. (815 aa)
	Frzb.S	Uncharacterized protein. (319 aa)
	nppa	Atrial natriuretic factor. (147 aa)
	aldh1a2	ALDH1A2 protein; Belongs to the aldehyde dehydrogenase family. (518 aa)
	myl1-2	MLC1f protein ( 3fprotein ). (190 aa)
	spry2-2	LOC398313 protein. (314 aa)
	lef1-2	Lymphoid enhancer factor XLEF-1. (372 aa)
	myl1	MGC53335 protein. (190 aa)
	sparc-2	MGC53121 protein. (300 aa)
	sparc	MGC64258 protein. (300 aa)
	ccnb2-2	MGC68601 protein; Belongs to the cyclin family. (392 aa)
	gata4-2	MGC81427 protein. (394 aa)
	dcn-2	Decorin; May affect the rate of fibrils formation. (364 aa)
	cdc16	Cdc16-prov protein. (621 aa)
	dcn	Decorin; May affect the rate of fibrils formation. (364 aa)
	axin2-2	MGC81576 protein. (707 aa)
	myh15	Ventricular myosin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	mespa	BHLH transcription factor mespa. (283 aa)
	socs1	Suppressor of cytokine signaling. (211 aa)
	LOC100189571	Uncharacterized protein. (608 aa)
	hand1	Heart and neural crest derivatives expressed 1. (197 aa)
	ins-2	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (106 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	lhx1	Homeobox protein. (403 aa)
	atp2a2	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
	lifr-2	Uncharacterized protein. (1091 aa)
	mef2c-2	MADS-box domain-containing protein. (464 aa)
	Sgcb.L	Uncharacterized protein. (327 aa)
	lifr	Uncharacterized protein. (1080 aa)
	mef2c	MADS-box domain-containing protein. (464 aa)
	Myl2.S	Uncharacterized protein. (167 aa)
	Myh6.S	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1934 aa)
	Alb.S	Uncharacterized protein. (607 aa)
	lef1	HMG box domain-containing protein. (372 aa)
	Tll1.S	Metalloendopeptidase. (1007 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	col2a1	Uncharacterized protein. (1486 aa)
	spry2	Uncharacterized protein. (307 aa)
	vangl1	Vang-like protein. (503 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8ENI4	Bmp2.L	A0A1L8ENI4	A0A1L8G5P4	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.432
A0A1L8ENI4	Dkk3.S	A0A1L8ENI4	A0A1L8GDZ7	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.527
A0A1L8ENI4	Frzb-1	A0A1L8ENI4	A0A1L8EWF4	Uncharacterized protein.	Uncharacterized protein.	0.459
A0A1L8ENI4	Frzb.S	A0A1L8ENI4	A0A1L8EPI8	Uncharacterized protein.	Uncharacterized protein.	0.459
A0A1L8ENI4	Wnt5b.S	A0A1L8ENI4	A0A1L8GQS0	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.601
A0A1L8ENI4	bmp2	A0A1L8ENI4	A0A1L8G1N2	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.432
A0A1L8ENI4	dkk1-2	A0A1L8ENI4	O57464	Uncharacterized protein.	Dickkopf homolog 1.	0.900
A0A1L8ENI4	fzd1	A0A1L8ENI4	A0A1L8FVQ7	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.677
A0A1L8ENI4	fzd2	A0A1L8ENI4	A0A1L8EL29	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.694
A0A1L8ENI4	fzd7	A0A1L8ENI4	A0A1L8EX17	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.652
A0A1L8ENI4	lef1	A0A1L8ENI4	A0A1L8HM07	Uncharacterized protein.	HMG box domain-containing protein.	0.922
A0A1L8ENI4	lef1-2	A0A1L8ENI4	Q90ZB8	Uncharacterized protein.	Lymphoid enhancer factor XLEF-1.	0.922
A0A1L8ENI4	wif1	A0A1L8ENI4	A0A1L8GYI2	Uncharacterized protein.	Uncharacterized protein.	0.723
A0A1L8ENI4	wif1-2	A0A1L8ENI4	B7ZPZ2	Uncharacterized protein.	Wnt inhibitory factor-1.	0.723
A0A1L8ENI4	wnt11	A0A1L8ENI4	A0A1L8HJX1	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.668
A0A1L8ENI4	wnt11b	A0A1L8ENI4	A0A1L8F6W4	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.667
A0A1L8ENI4	wnt3a	A0A1L8ENI4	A0A1L8FUX8	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.929
A0A1L8EUY4	Bmp2.L	A0A1L8EUY4	A0A1L8G5P4	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.432
A0A1L8EUY4	Dkk3.S	A0A1L8EUY4	A0A1L8GDZ7	Uncharacterized protein.	Dickkopf_N domain-containing protein.	0.527
A0A1L8EUY4	Frzb-1	A0A1L8EUY4	A0A1L8EWF4	Uncharacterized protein.	Uncharacterized protein.	0.459