24 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	casp3.2	Uncharacterized protein; Belongs to the peptidase C14A family. (288 aa)
	Casp3.L	Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
	wif1-2	Wnt inhibitory factor-1. (374 aa)
	dkk1-2	Dickkopf homolog 1. (259 aa)
	nck1	Cytoplasmic protein. (377 aa)
	nck1-2	Cytoplasmic protein. (377 aa)
	rac1	MGC114731 protein. (192 aa)
	ctnnb1	Beta-catenin protein. (781 aa)
	myc	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (420 aa)
	rhoa	MGC64296 protein. (193 aa)
	Gapdh.S	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	ccnd1	Ccnd1-prov protein; Belongs to the cyclin family. (291 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	c-Jun	C-Jun protein; Belongs to the bZIP family. (312 aa)
	dkk1	Dickkopf_N domain-containing protein. (263 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	Myc.S	Myc_N domain-containing protein. (176 aa)
	ryk	Uncharacterized protein. (596 aa)
	Dkk3.S	Dickkopf_N domain-containing protein. (257 aa)
	Lrp5.L	Uncharacterized protein. (1517 aa)
	Jun.L	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	wif1	Uncharacterized protein. (374 aa)
	nck2	Cytoplasmic protein. (381 aa)
	nck2-2	Cytoplasmic protein. (381 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Casp3.L	Gapdh.S	A0A1L8HU08	Q7ZY52	Uncharacterized protein; Belongs to the peptidase C14A family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.811
Casp3.L	Jun.L	A0A1L8HU08	A0A1L8GLZ4	Uncharacterized protein; Belongs to the peptidase C14A family.	BZIP domain-containing protein; Belongs to the bZIP family.	0.714
Casp3.L	Myc.S	A0A1L8HU08	A0A1L8FTW7	Uncharacterized protein; Belongs to the peptidase C14A family.	Myc_N domain-containing protein.	0.570
Casp3.L	c-Jun	A0A1L8HU08	Q9PVZ1	Uncharacterized protein; Belongs to the peptidase C14A family.	C-Jun protein; Belongs to the bZIP family.	0.715
Casp3.L	casp3.2	A0A1L8HU08	A0A1L8HLJ6	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.901
Casp3.L	ccnd1	A0A1L8HU08	Q8AVQ4	Uncharacterized protein; Belongs to the peptidase C14A family.	Ccnd1-prov protein; Belongs to the cyclin family.	0.732
Casp3.L	ctnnb1	A0A1L8HU08	Q63ZT4	Uncharacterized protein; Belongs to the peptidase C14A family.	Beta-catenin protein.	0.878
Casp3.L	gapdh	A0A1L8HU08	Q8AY70	Uncharacterized protein; Belongs to the peptidase C14A family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.811
Casp3.L	myc	A0A1L8HU08	Q6NRN4	Uncharacterized protein; Belongs to the peptidase C14A family.	Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.688
Casp3.L	rhoa	A0A1L8HU08	Q7SZA9	Uncharacterized protein; Belongs to the peptidase C14A family.	MGC64296 protein.	0.401
Casp3.L	wnt3a	A0A1L8HU08	A0A1L8FUX8	Uncharacterized protein; Belongs to the peptidase C14A family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.606
Dkk3.S	Lrp5.L	A0A1L8GDZ7	A0A1L8GJX4	Dickkopf_N domain-containing protein.	Uncharacterized protein.	0.873
Dkk3.S	ccnd1	A0A1L8GDZ7	Q8AVQ4	Dickkopf_N domain-containing protein.	Ccnd1-prov protein; Belongs to the cyclin family.	0.439
Dkk3.S	ctnnb1	A0A1L8GDZ7	Q63ZT4	Dickkopf_N domain-containing protein.	Beta-catenin protein.	0.726
Dkk3.S	dkk1	A0A1L8GDZ7	A0A1L8FIS6	Dickkopf_N domain-containing protein.	Dickkopf_N domain-containing protein.	0.917
Dkk3.S	dkk1-2	A0A1L8GDZ7	O57464	Dickkopf_N domain-containing protein.	Dickkopf homolog 1.	0.918
Dkk3.S	wif1	A0A1L8GDZ7	A0A1L8GYI2	Dickkopf_N domain-containing protein.	Uncharacterized protein.	0.803
Dkk3.S	wif1-2	A0A1L8GDZ7	B7ZPZ2	Dickkopf_N domain-containing protein.	Wnt inhibitory factor-1.	0.803
Dkk3.S	wnt3a	A0A1L8GDZ7	A0A1L8FUX8	Dickkopf_N domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.417
Gapdh.S	Casp3.L	Q7ZY52	A0A1L8HU08	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.811