42 items (Xenopus laevis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	grk5	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
	prkg1	cGMP-dependent protein kinase. (673 aa)
	A0A1L8FF79	cGMP-dependent protein kinase. (763 aa)
	A0A1L8FIB6	Uncharacterized protein. (833 aa)
	hspa5-2	Hspa5 protein; Belongs to the heat shock protein 70 family. (655 aa)
	ncs1	MGC78985 protein. (190 aa)
	MGC80314	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	git2	MGC80878 protein. (759 aa)
	grk4	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (575 aa)
	grk6-2	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (575 aa)
	LOC100037235	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	A0A1L8HZZ6	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
	Prkg2.L	cGMP-dependent protein kinase. (785 aa)
	A0A1L8HQ32	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
	Grk4.S	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (571 aa)
	grk1-2	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (557 aa)
	Git1	Uncharacterized protein. (737 aa)
	atp1a1	Sodium/potassium-transporting ATPase subunit alpha. (1025 aa)
	grk1	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (557 aa)
	Ahcyl1.S	Adenosylhomocysteinase. (489 aa)
	Atp1a1.S	Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1106 aa)
	grk5l-2	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (594 aa)
	calml4-2	Uncharacterized protein. (152 aa)
	grk6	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (575 aa)
	calml4	Uncharacterized protein. (153 aa)
	grk5l	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (594 aa)
	Itpr1.S	Uncharacterized protein. (2693 aa)
	Cyct.L	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (136 aa)
	cyct	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	A0A1L8FK17	cGMP-dependent protein kinase. (763 aa)
	cycs	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	cck	Gastrin domain-containing protein. (123 aa)
	Bcl2.S	BH4_2 domain-containing protein. (253 aa)
	A0A1L8FW52	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
	cck-2	Gastrin domain-containing protein. (128 aa)
	Erp44.L	Thioredoxin domain-containing protein. (407 aa)
	calm1	Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
	grk7	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (550 aa)
	plek	Uncharacterized protein. (350 aa)
	grk7-2	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (551 aa)
	mcl1	Uncharacterized protein. (277 aa)
	Mcl1.L	Uncharacterized protein. (277 aa)

Your Current Organism:

Xenopus laevis

NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L8FF79	Itpr1.S	A0A1L8FF79	A0A1L8GHJ0	cGMP-dependent protein kinase.	Uncharacterized protein.	0.456
A0A1L8FIB6	Git1	A0A1L8FIB6	A0A1L8HD66	Uncharacterized protein.	Uncharacterized protein.	0.840
A0A1L8FIB6	calm1	A0A1L8FIB6	A0A1L8G5X8	Uncharacterized protein.	Uncharacterized protein; Belongs to the calmodulin family.	0.505
A0A1L8FIB6	git2	A0A1L8FIB6	Q6GNU0	Uncharacterized protein.	MGC80878 protein.	0.720
A0A1L8FIB6	ncs1	A0A1L8FIB6	Q6IP34	Uncharacterized protein.	MGC78985 protein.	0.538
A0A1L8FK17	Itpr1.S	A0A1L8FK17	A0A1L8GHJ0	cGMP-dependent protein kinase.	Uncharacterized protein.	0.456
A0A1L8FW52	Bcl2.S	A0A1L8FW52	A0A1L8FSA4	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	BH4_2 domain-containing protein.	0.970
A0A1L8FW52	Itpr1.S	A0A1L8FW52	A0A1L8GHJ0	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Uncharacterized protein.	0.697
A0A1L8FW52	LOC100037235	A0A1L8FW52	A2VDE6	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Thioredoxin; Belongs to the thioredoxin family.	0.623
A0A1L8FW52	MGC80314	A0A1L8FW52	Q6GQ64	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Thioredoxin; Belongs to the thioredoxin family.	0.638
A0A1L8FW52	Mcl1.L	A0A1L8FW52	A0A1L8FBT2	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Uncharacterized protein.	0.886
A0A1L8FW52	calm1	A0A1L8FW52	A0A1L8G5X8	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Uncharacterized protein; Belongs to the calmodulin family.	0.710
A0A1L8FW52	calml4	A0A1L8FW52	A0A1L8GSE0	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Uncharacterized protein.	0.470
A0A1L8FW52	calml4-2	A0A1L8FW52	A0A1L8H184	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Uncharacterized protein.	0.470
A0A1L8FW52	hspa5-2	A0A1L8FW52	Q8AVE3	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Hspa5 protein; Belongs to the heat shock protein 70 family.	0.531
A0A1L8FW52	mcl1	A0A1L8FW52	A0A1L8F4J2	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	Uncharacterized protein.	0.886
A0A1L8HQ32	A0A1L8HZZ6	A0A1L8HQ32	A0A1L8HZZ6	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	0.900
A0A1L8HQ32	Git1	A0A1L8HQ32	A0A1L8HD66	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Uncharacterized protein.	0.809
A0A1L8HQ32	calm1	A0A1L8HQ32	A0A1L8G5X8	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	Uncharacterized protein; Belongs to the calmodulin family.	0.682
A0A1L8HQ32	git2	A0A1L8HQ32	Q6GNU0	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.	MGC80878 protein.	0.714